Results 61 to 70 of about 32,465 (166)

Fecal Enterotoxigenic Bacteroides fragilis–Peptostreptococcus stomatis–Parvimonas micra Biomarker for Noninvasive Diagnosis and Prognosis of Colorectal Laterally Spreading Tumor

Frontiers in Oncology, 2021
ObjectiveUp to now, non-invasive diagnosis of laterally spreading tumor (LST) and prediction of adenoma recurrence after endoscopic resection of LSTs is inevitable.
Xiaonan Shen, Jialu Li, Jiaqi Li, Yao Zhang, Xiaobo Li, Yun Cui, Qinyan Gao, Xiaoyu Chen, Yingxuan Chen, Jing-Yuan Fang   +9 more
doaj   +1 more source

Integrated In Vitro, In Vivo, and In Silico Study Reveals Gut‐Protective Effects of Myricitrin From Chinese Bayberry Leaves

Food Frontiers, Volume 7, Issue 2, March 2026.
High‐purity myricitrin from Chinese bayberry leaves alleviates colonic inflammation by preserving epithelial barrier integrity and reshaping gut microbiota composition. ABSTRACT Polyphenols have been widely recognized for their ability to modulate the host inflammatory response and orchestrate the intestinal microenvironment.
Ji‐Min Lv, Wei Quan, Xiao‐Hua Cheng, Jing Zhu, Aliyu Idris Muhammad, Wang‐Ting Zhou, Xing‐Jiang Qi, Chong‐De Sun   +7 more
wiley   +1 more source

Drug Discovery and Repurposing Inhibits a Major Gut Pathogen-Derived Oncogenic Toxin

Frontiers in Cellular and Infection Microbiology, 2019
Objective: The human intestinal microbiome plays an important role in inflammatory bowel disease (IBD) and colorectal cancer (CRC) development. One of the first discovered bacterial mediators involves Bacteroides fragilis toxin (BFT, also named as ...
Paul Metz, Paul Metz, Paul Metz, Martijn J. H. Tjan, Martijn J. H. Tjan, Shaoguang Wu, Mehrosh Pervaiz, Susanne Hermans, Aishwarya Shettigar, Cynthia L. Sears, Tina Ritschel, Bas E. Dutilh, Bas E. Dutilh, Annemarie Boleij   +13 more
doaj   +1 more source

A highly conserved SusCD transporter determines the import and species-specific antagonism of Bacteroides ubiquitin homologues

Nature Communications
Efficient interbacterial competitions and diverse defensive strategies employed by various bacteria play a crucial role in acquiring a hold within a dense microbial community.
Ming Tong, Jinghua Xu, Weixun Li, Kun Jiang, Yan Yang, Zhe Chen, Xuyao Jiao, Xiangfeng Meng, Mingyu Wang, Jie Hong, Hongan Long, Shuang-Jiang Liu, Bentley Lim, Xiang Gao   +13 more
doaj   +1 more source

Receptor-guided proteolysis at the host-gut microbiota interface: insights from the Bacteroides fragilis toxin-claudin-4 axis

Targetome
Enterotoxigenic Bacteroides fragilis (ETBF) is a colorectal cancer-associated bacterium whose pathogenicity depends largely on B. fragilis toxin (BFT), a secreted metalloprotease that cleaves E-cadherin and disrupts epithelial barrier integrity.
Danni Tong, Weiwei Zheng, Frank J. Gonzalez, Yuhong Luo   +3 more
doaj   +1 more source

Targeting Microbiome Metabolites: Reshaping Immunotherapy and Clinical Management Strategies for Colorectal Cancer

iMetaMed, Volume 2, Issue 1, March 2026.
The occurrence and progression of colorectal cancer are intricately linked to metabolites produced by the gut microbiota. Metabolites generated by pathogenic microbial communities can promote colorectal cancer development by reshaping the immune microenvironment.
Xinrui Yang, Ke Zhang, Lijie Xia, Jinyao Li   +3 more
wiley   +1 more source

DNA repair in bacteroides fragilis [PDF]

, 2008
Includes abstract.Includes bibliographical leaves (leaves 89-101).Bacteroides fragilis is a gut commensal in both humans and animals where it benefits the host through metabolizing indigestible compounds, stimulating the immune system and protecting ...
Steffens, Laura Sione
core   +1 more source

Gastrointestinal Pathobionts in Pediatric Crohn’s Disease Patients

International Journal of Microbiology, 2018
Crohn’s disease (CD) is an inflammatory disease of the gastrointestinal tract, with a rising incidence worldwide, particularly in children. CD is thought to arise due to an immune response to environmental factors. The role of bacteria in CD has recently
Rachel V. Purcell, Nadeem O. Kaakoush, Hazel M. Mitchell, John F. Pearson, Jacqueline I. Keenan   +4 more
doaj   +1 more source

Harnessing Next‐Generation 3D Cancer Models to Elucidate Tumor‐Microbiome Crosstalk

Advanced Healthcare Materials, Volume 15, Issue 1, 9 January 2026.
Centralizes the microbiome within 3D tumor‐microbiome model platforms, including spheroids, organoids, 3D‐bioprinted constructs, and microfluidic chips, each enabling structured host‐tumor‐microbe studies. These systems support bacterial colonization, facilitating investigation of microbial impacts on tumor growth, immunity, and therapy. The microbiome
Marina Green Buzhor, Giuseppe Longobardi, Or Kandli, Anne Krinsky, Opal Avramoff, Anshika Katyal, Koren Salomon, Adan Miari, Dana Venkert, Tania T. Barnatan, América García Alvarado, Shahar Greenberg, Ronit Satchi‐Fainaro   +12 more
wiley   +1 more source

Progress in the detection of gut microbiota based on microfluidic technology

Interdisciplinary Medicine, Volume 4, Issue 1, January 2026.
Abstract Gut microbiota, a complex microbial community in the human intestine, are vital for digestion, nutrient absorption, and immune regulation, maintaining gut micro‐ecological balance. Accurate detection of its composition, structure, and function is crucial for understanding the relationship between health and disease, early disease diagnosis ...
Yuan Tan, Jiayue Huang, Yi Liu, Xiaofei Lai   +3 more
wiley   +1 more source