Results 41 to 50 of about 32,465 (166)

Colonization with enterotoxigenic Bacteroides fragilis is associated with early-stage colorectal neoplasia.

PLoS ONE, 2017
BackgroundEnterotoxigenic Bacteroides fragilis (ETBF) is a toxin-producing bacteria thought to possibly promote colorectal carcinogenesis by modulating the mucosal immune response and inducing epithelial cell changes.
Rachel V Purcell, John Pearson, Alan Aitchison, Liane Dixon, Frank A Frizelle, Jacqueline I Keenan   +5 more
doaj   +1 more source

Bacteroides fragilis Toxin Induces Cleavage and Proteasome Degradation of E-cadherin in Human Breast Cancer Cell Lines BT-474 and MCF7

Korean Journal of Clinical Laboratory Science, 2023
Enterotoxigenic Bacteroides fragilis (ETBF) has been reported to promote colitis and colon cancer through the secretion of B. fragilis toxin (BFT), a zinc-dependent metalloprotease. In colonic epithelial cells, BFT induces the cleavage of E-cadherin into
Da-Hye KANG, Sang-Hyeon YOO, Ju-Eun HONG, Ki-Jong RHEE   +3 more
doaj   +1 more source

Microbiome and Tumor Microenvironment Interactions: Advances From Ecological Niches to Precision Oncology

Cancer Nexus, Volume 2, Issue 4, October 2026.
Tumor‐associated microbiota occupies spatially organized ecological niches and influence cancer progression by reshaping tumor‐cell signaling, metabolism, immunity, stromal remodeling, and therapeutic response. Integrating microbiome‐derived biomarkers, targeted microbial interventions, spatial multi‐omics, longitudinal monitoring, and AI may enable ...
Yiwen Zhang, Ji'an Liu, Jing Li, Xue Liu, Yang Su, Peng Luo, Yuhan Zhang, Zhengrui Li   +7 more
wiley   +1 more source

A systemic review of the role of enterotoxic Bacteroides fragilis in colorectal cancer

Neoplasia: An International Journal for Oncology Research, 2022
Enterotoxigenic Bacteroides fragilis (ETBF) has received significant attention for a possible association with, or causal role in, colorectal cancer (CRC).
Nancy Scott, Emma Whittle, Patricio Jeraldo, Nicholas Chia   +3 more
doaj   +1 more source

Cancer Cell Metastasis: From Molecular Mechanisms to Therapeutic Strategies

MedComm, Volume 7, Issue 10, October 2026.
The schematic representation of intrinsic and extrinsic influences of cancer cell metastasis. Genomic evolution of metastatic tumor cells (MTCs) promotes their metastatic phenotypes and reconstruct the primary tumor microenvironment. During MTCs migration along different routes (blood circulation, lymphatic vessels, and perineuronal spaces), the ...
Yupeng Zhao, Wenchao Xu, Yibo Wang, Haoran Huang, Yu Su, Li Zhou, Jianzhou Liu, Junchao Guo   +7 more
wiley   +1 more source

High frequency of enterotoxigenic Bacteroides fragilis and Enterococcus faecalis in the paraffin-embedded tissues of Iranian colorectal cancer patients

BMC Cancer, 2021
Background The association between specific bacteria and colorectal cancer (CRC) has been proposed. Only a few studies have, however, investigated this relationship directly in colorectal tissue with conflicting results.
Nasibeh Khodaverdi, Habib Zeighami, Ahmad Jalilvand, Fakhri Haghi, Negar Hesami   +4 more
doaj   +1 more source

Bacteriodes fragilis interactions with the collagen type I component of the host extracellular matrix [PDF]

, 2010
Includes bibliographical references (p. 116-126).Bacteroides fragilis is an opportunistic pathogen which can cause life threatening infections in humans and animals.
Galvao, Bruna Patricia Gomes de Vasconcelos
core   +1 more source

Toxigenic and non-toxigenic patterns I, II and III and biofilm-forming ability in Bacteroides fragilis strains isolated from patients diagnosed with colorectal cancer

Gut Pathogens, 2020
Background Enterotoxigenic Bacteroides fragilis (ETBF) associated with the initiation and progression of colorectal cancer (CRC) has been alarmingly reported all over the world.
Seyedesomaye Jasemi, Mohammad Emaneini, Mohammad Sadegh Fazeli, Zahra Ahmadinejad, Bizhan Nomanpour, Fatemah Sadeghpour Heravi, Leonardo A. Sechi, Mohammad Mehdi Feizabadi   +7 more
doaj   +1 more source

N6‐Methyladenosine in Inflammatory Bowel Disease: An Emerging Regulator of Pathogenesis and a Novel Therapeutic Frontier

iMetaMed, Volume 2, Issue 3, September 2026.
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the intestine associated with an imbalance in intestinal homeostasis. m6A‐modifying enzymes, consisting of m6A writers, erasers and readers, plays a pivotal role in the pathogenesis and progression of IBD by affecting four intestinal barriers, including the intestinal mechanical ...
Jiaxian Guo, Yang Zhang, Xin Wang, Shan Cao, Jun Xu   +4 more
wiley   +1 more source

Microbial Signals in Cancer: Dissecting Host–Microbiota–Tumor Interactions and Potential Therapeutic Strategy

MedComm, Volume 7, Issue 9, September 2026.
Microbial signals from gut and tumor‐resident bacteria, fungi, viruses, and bacteriophages reshape immune and metabolic networks within the tumor microenvironment, thereby influencing cancer progression, treatment response. Therapeutic modulations, including dietary interventions, probiotics, antibiotics, fecal microbiota transplantation, engineered ...
Juan Lu, Mengjuan Xuan, Liang Yu, Zhongyang Xie, Qingfei Chu, Shihui Wei, Tuokai Wang, Chen Xue, Lanjuan Li   +8 more
wiley   +1 more source