Results 21 to 30 of about 72,749 (175)

The TLR3/IRF1/Type III IFN Axis Facilitates Antiviral Responses against Enterovirus Infections in the Intestine

mBio, 2020
Enteroviruses infect gastrointestinal epithelium cells, cause multiple human diseases, and present public health risks worldwide. However, the mechanisms underlying host immune responses in intestinal mucosa against the early enterovirus infections ...
Rui Su, Muhammad Adnan Shereen, Xiaofeng Zeng, Yicong Liang, Wen Li, Zhihui Ruan, Yongkui Li, Weiyong Liu, Yingle Liu, Kailang Wu, Zhen Luo, Jianguo Wu   +11 more
doaj   +1 more source

Sensitive detection systems for infectious agents in xenotransplantation*

Xenotransplantation, EarlyView., 2020
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley   +1 more source

Research progress on the quality control of mRNA vaccines

Expert Review of Vaccines
Introduction The mRNA vaccine technologies have progressed rapidly in recent years. The COVID-19 pandemic has accelerated the application of mRNA vaccines, with research and development and clinical trials underway for many vaccines.
Chaoying Hu, Yu Bai, Jianyang Liu, Yiping Wang, Qian He, Xuanxuan Zhang, Feiran Cheng, Miao Xu, Qunying Mao, Zhenglun Liang   +9 more
doaj   +1 more source

Enterovirus infection in the Socialist Republic of Vietnam

Инфекция и иммунитет, 2019
Human enterovirus infections comprise a group of infectious diseases caused by viruses of Enterovirus A-D species (genus Enterovirus, family Picornaviridae).
L. N. Golitsyna, T. T.T. Nguyen, N. I. Romanenkova, M. T. Luong, L. T. Vu, O. I. Kanaeva, M. A. Bichurina, N. A. Novikova   +7 more
doaj   +1 more source

Natural Clearance of Prolonged VDPV Infection in a Child With Primary Immunodeficiency Disorder

Frontiers in Immunology, 2019
The emergence of immunodeficiency-associated vaccine-derived polioviruses (iVDPV) from children with primary immunodeficiency disorders poses a threat to the eradication program.
Madhu Chhanda Mohanty, Manisha Ranjan Madkaikar, Mukesh Desai, Jahnavi Aluri, Swapnil Yashwant Varose, Prasad Taur, Deepa Kailash Sharma, Uma Prajwal Nalavade, Sneha Vijay Rane, Maya Gupta, Snehal Shabarish, Aparna Dalvi, Jagadish Mohanrao Deshpande   +12 more
doaj   +1 more source

Human Enterovirus B: Selective Inhibition by Quinoxaline Derivatives and Bioinformatic RNA-Motif Identification as New Targets

Pharmaceuticals, 2022
The Enterovirus genus includes many viruses that are pathogenic in humans, including Coxsackie viruses and rhinoviruses, as well as the emerging enteroviruses D68 and A71.
Silvia Madeddu, Roberta Ibba, Giuseppina Sanna, Sandra Piras, Federico Riu, Alessandra Marongiu, Annalisa Ambrosino, Paola Caria, Valentina Onnis, Gianluigi Franci, Aldo Manzin, Antonio Carta   +11 more
doaj   +1 more source

Modern epidemiological features of viral acute intestinal infections in children and adolescents of Sakhalin region

Журнал инфектологии
Objective: to identify modern epidemiological features of viral acute intestinal infections in children and adolescents in the Sakhalin Region.Materials and methods.
E. Yu. Sapega, L. V. Butakova, O. E. Trotsenko   +2 more
doaj   +1 more source

Enterovirus infection morbidity and peculiarities of nonpolio enteroviruses circulation on some territories of Russia in 2017

Журнал инфектологии, 2018
Aim: Characteristics of enterovirus infection morbidity and study of peculiarities of enterovirus circulation on some territories of Russia in 2017.
N. I. Romanenkova, L. N. Golitsyna, M. A. Bichurina, N. R. Rozaeva, O. I. Kanaeva, V. V. Zverev, D. V. Sozonov, I. V. Cherkasskaya, L. P. Kirillova, M. V. Ermakova, L. S. Kamynina, M. B. Petukhova, A. B. Gritsay, N. A. Novikova   +13 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source