Results 51 to 60 of about 72,749 (175)

Molecular Analysis of Caprine Enterovirus Circulating in China during 2016–2021: Evolutionary Significance

open access: yesViruses, 2022
Here, we report the characterization of 13 novel caprine/ovine enterovirus strains isolated from different regions in China during 2016–2021. Immunoperoxidase monolayer assay showed that these viral strains shared strong cross-reaction with the ...
Xiaoran Chang   +7 more
doaj   +1 more source

Curcuminoids amplify host innate antiviral immunity via the CRYAB‐RBM26 axis in viral infection

open access: yesiMeta, EarlyView.
DMC/CUR antagonize viral hijacking of host nucleic acid resources and finely regulate the induction and effector phases of the type I interferon (IFN‐I) pathway through the CRYAB‐RBM26 axis. This molecular axis serves as a key downstream regulator for DMC/CUR activation of the IFN‐I pathway.
Tingting Chen   +18 more
wiley   +1 more source

Accuracy of Diagnostic Methods and Surveillance Sensitivity for Human Enterovirus, South Korea, 1999–2011

open access: yesEmerging Infectious Diseases, 2013
The epidemiology of enteroviral infection in South Korea during 1999–2011 chronicles nationwide outbreaks and changing detection and subtyping methods used over the 13-year period.
Ji-Yeon Hyeon   +16 more
doaj   +1 more source

When protein losing enteropathy persists: A case series of viral and lymphatic‐associated etiologies

open access: yesJPGN Reports, EarlyView.
Abstract Protein‐losing enteropathy (PLE) is a rare condition that is characterized by loss of plasma protein in the intestines leading to hypoproteinemia with subsequent peripheral edema and possibly anasarca. The pathophysiology of PLE varies depending on the etiology and involves either intestinal mucosal injury or lymphatic system alterations ...
Natalie Jennings   +7 more
wiley   +1 more source

Risk of Nephrotic Syndrome following Enteroviral Infection in Children: A Nationwide Retrospective Cohort Study.

open access: yesPLoS ONE, 2016
PurposeNephrotic syndrome is a common chronic illness encountered during childhood. Infections have been identified as a cause of nephrotic syndrome.
Jiun-Nong Lin   +6 more
doaj   +1 more source

Deferoxamine Compensates for Decreases in B Cell Counts and Reduces Mortality in Enterovirus 71-Infected Mice

open access: yesMarine Drugs, 2014
Enterovirus 71 is one of the major causative agents of hand, foot and mouth disease in children under six years of age. No vaccine or antiviral therapy is currently available.
Yajun Yang   +7 more
doaj   +1 more source

Reactive Infectious Mucocutaneous Eruption (RIME): An Australian Case Series

open access: yesAustralasian Journal of Dermatology, EarlyView.
ABSTRACT Whilst Reactive Infectious Mucocutaneous Eruption (RIME) displays a low mortality rate, the condition results in significant morbidity and resource allocation, including prolonged hospital admission. As such, early diagnosis and optimisation of treatment is imperative.
Hamish Moore   +2 more
wiley   +1 more source

SARS‐CoV‐2 nucleocapsid protein variants have differential RNA chaperone activity

open access: yesThe FEBS Journal, EarlyView.
The SARS‐CoV‐2 nucleocapsid (N) protein facilitates RNA annealing through its RBD–IDR2–CTD region, identifying it as a functional RNA chaperone. The Omicron BA.5 variant shows reduced chaperone activity compared to the Wuhan wild‐type protein. Although phosphorylation has no effect on wild‐type N, phosphomimetic modification of BA.5 N restores its RNA ...
Sabrina Babl   +11 more
wiley   +1 more source

Enterovirus RNA in peripheral blood may be associated with the variants of rs1990760, a common type 1 diabetes associated polymorphism in IFIH1.

open access: yesPLoS ONE, 2012
ObjectivePolymorphisms in the IFIH1 (common rs1990760 and four rare rs35667974, rs35337543, rs35744605, rs35732034) have been convincingly associated with type 1 diabetes.
Ondrej Cinek   +7 more
doaj   +1 more source

Epigenetic analyses suggest different pathways during pregnancy for development of Type 1 diabetes in children with high versus low‐neutral human leukocyte antigen‐risk

open access: yesJournal of Internal Medicine, EarlyView.
Abstract Background and objective The development of Type 1 diabetes (T1D) is shaped by genetic predisposition and epigenetic regulation. Human leukocyte antigen (HLA) risk alleles are major genetic determinants, but the epigenetic landscape in relation to disease onset remains unclear.
Shamila D. Alipoor   +6 more
wiley   +1 more source

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