Results 201 to 210 of about 69,989 (234)

Recent advances in enterovirus A71 pathogenesis: a focus on fatal human enterovirus A71 infection

Archives of Virology, 2022
Enterovirus A71 (EV-A71) is one of the major pathogens responsible for hand, foot, and mouth disease (HFMD). Many HFMD outbreaks have been reported throughout the world in the past decades. Compared with other viruses, EV-A71 infection is more frequently associated with severe neurological complications and even death in children.
Jingjun Xing, Ke Wang, Geng Wang, Na Li, Yanru Zhang   +4 more
openaire   +2 more sources

A novel human enterovirus recombinant from a child with diarrhea

Archives of Virology, 2013
Recombination is a well-known phenomenon for enteroviruses. In the present study, a novel recombinant HEV-B strain (ChZJ-1) was found in a 2-year-old child with diarrhea in Zhenjiang, China. The whole genome of ChZJ-1 was determined. Recombination and phylogenetic analysis revealed that ChZJ-1 might have been produced by recombination between ...
Guangming, Sun, Maoli, Yi, Hua, Tian, Chen, Shao, Shixing, Yang, Jun, Han, Xiaochun, Wang, Yong, Wang, Quan, Shen, Hua, Wang, Shihe, Shao, Yan, Yang, Wen, Zhang   +12 more
openaire   +2 more sources

Motor development of children after a human Parechovirus or Enterovirus infection: 24 months follow-up

Minerva Pediatrics, 2023
Human Parechovirus (HPeV) and Enterovirus (EV) are known causes of viral infection and meningitis in childhood. Not much is known about the motor development of young Caucasian children after these infections. Most studies in the literature involved Asian children with only EV-71 infection, which is not prevalent in Western countries.In this ...
de Crom, Stephanie C., van Hinsbergh, M. Ted, van Beijsterveldt, Inge A., van Furth, A. Marceline, Rossen, John W., Obihara, Charlie C.   +5 more
openaire   +4 more sources

Fatal Neonatal Myocarditis Caused by a Recombinant Human Enterovirus-B Variant

Pediatric Infectious Disease Journal, 2008
We report a case of fatal myocarditis in a newborn infant who was infected with a human enterovirus detected by throat culture and RT-PCR for viral RNA in plasma. Whole genome sequence analysis revealed the virus to be a genomic chimera that likely arose from recombination between coxsackievirus B3 and two recently identified enteroviruses, EV 86 and ...
Paul, Krogstad, Rebecca, Hammon, Nancy, Halnon, J Lindsay, Whitton   +3 more
openaire   +2 more sources

Increased Virulence of a Human Enterovirus (Coxsackievirus B3) in SeleniumDeficient Mice

Journal of Infectious Diseases, 1994
Coxsackievirus B3 (CVB3/20)-induced myocarditic lesions occurred more quickly and were more severe and virus titers in heart and liver were higher in selenium (Se)-deficient than Se-adequate mice. NK cell activity and serum neutralizing antibody titers were similar in both Se-adequate and -deficient CVB3/20-infected mice; however, lymphocyte ...
M A, Beck, P C, Kolbeck, Q, Shi, L H, Rohr, V C, Morris, O A, Levander   +5 more
openaire   +2 more sources

A reverse genetics system for enterovirus D68 using human RNA polymerase I

Virus Genes, 2018
Human enterovirus D68 (EV-D68) is a highly contagious virus, which causes respiratory tract infections. However, no effective vaccines are currently available for controlling EV-D68 infection. Here, we developed a reverse genetics system to recover EV-D68 minireplicons and infectious EV-D68 from transfected plasmids using the RNA polymerase I (Pol I ...
Minglei, Pan, Shuai, Gao, Zhenwei, Zhou, Keke, Zhang, Sihua, Liu, Zhiyun, Wang, Tao, Wang   +6 more
openaire   +2 more sources

A New Candidate Type of Human Enterovirus (Drilon Strain) Isolated in the Philippines

Microbiology and Immunology, 1981
AbstractA cytopathogenic agent was isolated in monkey kidney (MK) cell cultures from the stool specimen of a 3‐month‐old Filipina hospitalized with lower respiratory disease. The agent was designated the Drilon strain. It was characterized as an enterovirus on the basis of electron microscopic morphology, nucleic acid type (RNA), resistance to ether ...
J C, Nakao, M, Hara, I, Tagaya, G W, Beran, F F, Macasaet   +4 more
openaire   +2 more sources

Generation and characterization of a protective mouse monoclonal antibody against human enterovirus 71

Applied Microbiology and Biotechnology, 2015
Human enterovirus 71 (EV71) infection has emerged as a major threat to children; however, no effective antiviral treatment or vaccine is currently available. Antibody-based treatment shows promises to control this growing public health problem of EV71 infection, and a few potent monoclonal antibodies (mAbs) targeting viral capsid protein have been well
Yong-Qiang, Deng, Jie, Ma, Li-Juan, Xu, Yue-Xiang, Li, Hui, Zhao, Jian-Feng, Han, Jiang, Tao, Xiao-Feng, Li, Shun-Ya, Zhu, E-De, Qin, Cheng-Feng, Qin   +10 more
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Characterization of a monoclonal antibody against the 3D polymerase of enterovirus 71 and its use for the detection of human enterovirus A infection

Journal of Virological Methods, 2012
Over the last decade, frequent epidemic outbreaks of hand, foot and mouth disease have been observed in the Asia-Pacific region. Hand, foot and mouth disease is caused by different viruses from the enterovirus family, mainly coxsackievirus A16 and enterovirus 71 (EV71) from the human enterovirus A family.
Tanja K, Kiener, Xiao Fang, Lim, Qiang, Jia, Tao, Meng, Vincent Tak Kwong, Chow, Jimmy, Kwang   +5 more
openaire   +2 more sources

Enterovirus 71 transmission by exosomes establishes a productive infection in human neuroblastoma cells

Virus Genes, 2016
Exosomes are small secreted cellular vesicles for intercellular communications which contain proteins, mRNAs, and microRNAs (miRNAs). Recent studies have shown that exosomes play an important role in the transmission of infectious agents including hepatitis C virus, human immunodeficiency virus, and so on.
Lingxiang, Mao, Jing, Wu, Li, Shen, Jing, Yang, Jianguo, Chen, Huaxi, Xu   +5 more
openaire   +2 more sources