Results 31 to 40 of about 69,989 (234)

Genetic characterization of human coxsackievirus A6 variants associated with atypical hand, foot and mouth disease: a potential role of recombination in emergence and pathogenicity [PDF]

, 2015
Human coxsackievirus A6 (CVA6) is an enterically transmitted enterovirus. Until recently, CVA6 infections were considered as being of minor clinical significance, and only rarely aetiologically linked with hand, foot and mouth disease (HFMD) associated ...
Gaunt, E, Harvala, H, Simmonds, P, Sreenu, VB, Thomson, E, Waris, M, Österback, R   +6 more
core   +1 more source

Multicenter Evaluation of the QIAstat-Dx Respiratory Panel for the Detection of Viruses and Bacteria in Nasopharyngeal Swab Specimens [PDF]

, 2020
The QIAstat-Dx Respiratory Panel (QIAstat-Dx RP) is a multiplex in vitro diagnostic test for the qualitative detection of 20 pathogens directly from nasopharyngeal swab (NPS) specimens. The assay is performed using a simple sample-to-answer platform with
Granato, Paul, Hannet, Irene, Hansen, Glen, Leber, Amy L., Lisby, Jan Gorm, Pareja, Josep, Relich, Ryan F., Schneider, Uffe Vest, Young, Stephen   +8 more
core   +1 more source

Structure of human enterovirus 71 in complex with a capsid-binding inhibitor [PDF]

Proceedings of the National Academy of Sciences, 2013
Human enterovirus 71 is a picornavirus causing hand, foot, and mouth disease that may progress to fatal encephalitis in infants and small children. As of now, no cure is available for enterovirus 71 infections. Small molecule inhibitors binding into a hydrophobic pocket within capsid viral protein 1 were previously shown to effectively limit ...
Pavel, Plevka, Rushika, Perera, Moh Lan, Yap, Jane, Cardosa, Richard J, Kuhn, Michael G, Rossmann   +5 more
openaire   +2 more sources

Retrospective Surveillance of Wastewater To Examine Seasonal Dynamics of Enterovirus Infections

mSphere, 2017
Enteroviruses are RNA viruses that are responsible for both mild gastroenteritis and mild respiratory illnesses as well as debilitating diseases such as meningitis and myocarditis.
Nichole E. Brinkman, G. Shay Fout, Scott P. Keely   +2 more
doaj   +1 more source

Myocarditis, disseminated infection, and early viral persistence following experimental coxsackievirus B infection of cynomolgus monkeys. [PDF]

, 2013
Coxsackievirus B (CVB) infection is a common cause of acute viral myocarditis. The clinical presentation of myocarditis caused by this enterovirus is highly variable, ranging from mildly symptoms to complete hemodynamic collapse.
Blanchard, James, Bohm, Rudolf, Cammock, Cheryl E, Halnon, Nancy J, Krogstad, Paul A, Lai, Chi, Miller, Christopher J, Skoczylas, Jill   +7 more
core   +2 more sources

Identification and Typing of Human Enterovirus: A Genomic Barcode Approach

PLoS ONE, 2011
Identification and typing of human enterovirus (HEVs) are important to pathogen detection and therapy. Previous phylogeny-based typing methods are mainly based on multiple sequence alignments of specific genes in the HEVs, but the results are not stable with respect to different choices of genes.
Wei C., Wang G., Chen X., Huang H., Liu B., Xu Y., Li F.   +6 more
openaire   +5 more sources

Antibodies to Enteroviruses in Cerebrospinal Fluid of Patients with Acute Flaccid Myelitis. [PDF]

, 2019
Acute flaccid myelitis (AFM) has caused motor paralysis in >560 children in the United States since 2014. The temporal association of enterovirus (EV) outbreaks with increases in AFM cases and reports of fever, respiratory, or gastrointestinal illness
Briese, Thomas, Burns, Jane C, Caciula, Adrian, Garcia, Joel A, Hetzler, Kimbell L, Jain, Komal, Konopka-Anstadt, Jennifer L, Lipkin, W Ian, Marine, Rachel L, Mishra, Nischay, Ng, James, Ng, Terry Fei Fan, Nix, W Allan, Oberste, M Steven, Price, Adam, Routh, Janell A, Thakkar, Riddhi, Thakkar, Roshni, Thakur, Kiran T, Tokarz, Rafal   +19 more
core   +2 more sources

Simultaneous detection of enterovirus-D68 and vaccine-related poliovirus 3 in the stool samples of a 5-month hospitalized child with acute respiratory disease: A case report

Biosafety and Health, 2023
Human enterovirus (EV) infections can lead to various manifestations, with variable correlations between genotypes and symptoms. Human enterovirus D68 (EV-D68) was considered to be associated with acute respiratory disease and acute flaccid myelitis.
Wenzhe Su, Qing Zeng, Jinmei Geng, Jingwen Liu, Huaping Xie, Kuibiao Li, Pengzhe Qin, Chaojun Xie, Biao Di   +8 more
doaj   +1 more source

Seroprevalence of Enterovirus D68 Infection among Humans: A Systematic Review and Meta-Analysis

Intervirology, 2023
Introduction: Human enterovirus D68 (EV-D68), which belongs to enteroviruses of the small RNA family, is a type of enterovirus that can cause acute respiratory tract infection and central nervous system diseases. This study systematically analysed and summarized EV-D68 antibody studies in databases and identified the seropositivity rates of different ...
Yingying Shi, Qinqin Ran, Xiaochen Wang, Lu Shi   +3 more
openaire   +3 more sources

A murine model for the human enterovirus 71 encephalomyelitis

BMC Proceedings, 2008
Address: 1Department of Pathology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia, 2Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia, 3Laboratory Animal Centre, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia and 4Insitute of Health and Community
Kien Chai Ong, Badmanathan Munisamy, Shamala Devi, Kum Loong Leong, Mary Jane Cardosa, Kum Thong Wong   +5 more
openaire   +1 more source