Results 61 to 70 of about 69,989 (234)

Recombination strategies and evolutionary dynamics of the Human enterovirus A global gene pool

Journal of General Virology, 2014
We analysed natural recombination in 79 Human enterovirus A strains representing 13 serotypes by sequencing of VP1, 2C and 3D genome regions. The half-life of a non-recombinant tree node in coxsackieviruses 2, 4 and 10 was only 3.5 years, and never more than 9 years.
A. N. Lukashev, E. Y. Shumilina, I. S. Belalov, O. E. Ivanova, T. P. Eremeeva, V. I. Reznik, O. E. Trotsenko, J. F. Drexler, C. Drosten   +8 more
openaire   +2 more sources

Pan-viral serology implicates enteroviruses in acute flaccid myelitis. [PDF]

, 2019
Since 2012, the United States of America has experienced a biennial spike in pediatric acute flaccid myelitis (AFM)1-6. Epidemiologic evidence suggests non-polio enteroviruses (EVs) are a potential etiology, yet EV RNA is rarely detected in cerebrospinal
Banerji, Debarko, Benson, Leslie, Bove, Riley, Briggs, Benjamin, Cheung, Carly K, Chitnis, Tanuja, Chiu, Charles Y, Chu, Victoria, Crawford, Emily D, DeRisi, Joseph L, Ding, Joy Z, Dominguez, Samuel R, Gelfand, Amy A, Glaser, Carol A, Gorman, Mark P, Hauser, Stephen L, Hawes, Isobel A, Johnson-Kerner, Bethany L, Khan, Lillian M, Konopka-Anstadt, Jennifer L, Krishnamoorthy, Kalpathy S, Lopez, Adriana S, Lyden, Amy, Marine, Rachel L, McMillan, Hugh J, Messacar, Kevin, Nash, Kendall, Ng, Terry Fei Fan, Nix, W Allan, O'Donovan, Brian D, Oberste, M Steven, Pak, John E, Ramachandran, Prashanth S, Ramesh, Akshaya, Sample, Hannah A, Schubert, Ryan D, Sit, Rene, Soldatos, Ariane, Sowa, Gavin M, Tan, Michelle, Tato, Cristina M, Wadford, Debra A, Wilson, Michael R, Wu, Wesley, Yen, Cynthia, Zorn, Kelsey C   +45 more
core  

A novel mechanism underlying the innate immune response induction upon viral-dependent replication of host cell mRNA: A mistake of +sRNA viruses' replicases [PDF]

, 2017
Viruses are lifeless particles designed for setting virus-host interactome assuring a new generation of virions for dissemination. This interactome generates a pressure on host organisms evolving mechanisms to neutralize viral infection, which places the
Colombo, Maria Isabel, Delgui, Laura Ruth   +1 more
core   +2 more sources

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Human adenovirus (HAdV), human enterovirus (hEV), and genogroup A rotavirus (GARV) in tap water in southern Brazil [PDF]

Journal of Water and Health, 2014
The effects of viral gastroenteritis are more devastating in children than in any other age category. Thus, children exposed to the consumption of low quality water are at an increased risk of infection, especially in regions where sanitation is inadequate. The present study aimed to provide a survey of the occurrence of representative enteric viruses:
M, Kluge, J D, Fleck, M C, Soliman, R B, Luz, R B, Fabres, J, Comerlato, J V S, Silva, R, Staggemeier, A D, Vecchia, R, Capalonga, A B, Oliveira, A, Henzel, C, Rigotto, F R, Spilki   +13 more
openaire   +2 more sources

Pathogenesis Study of Enterovirus 71 Using a Novel Human SCARB2 Knock-In Mouse Model

mSphere, 2021
Enterovirus 71 (EV71) is associated with severe hand-foot-mouth disease. Recently, outbreaks of EV71 infection with high mortality have been reported in the Asia-Pacific region, posing a great challenge for global public health.
Yuefei Jin, Tiantian Sun, Guangyuan Zhou, Dong Li, Shuaiyin Chen, Weiguo Zhang, Xueyuan Li, Rongguang Zhang, Haiyan Yang, Guangcai Duan   +9 more
openaire   +3 more sources

Enterovirus virus-like-particle and inactivated poliovirus vaccines do not elicit substantive cross-reactive antibody responses.

PLoS Pathogens
Human enteroviruses are the most common human pathogen with over 300 distinct genotypes. Previous work with poliovirus has suggested that it is possible to generate antibody responses in humans and animals that can recognize members of multiple ...
Daniel L Moss, Alden C Paine, Peter W Krug, Masaru Kanekiyo, Tracy J Ruckwardt   +4 more
doaj   +1 more source

Acute flaccid paralysis with anterior myelitis - California, June 2012-June 2014. [PDF]

, 2014
In August 2012, the California Department of Public Health (CDPH) was contacted by a San Francisco Bay area clinician who requested poliovirus testing for an unvaccinated man aged 29 years with acute flaccid paralysis (AFP) associated with anterior ...
Ayscue, Patrick, Centers for Disease Control and Prevention (CDC), Clayton, Anna, Feikin, Daniel, Glaser, Carol, Harriman, Kathleen, Nix, William Allan, Padilla, Tasha, Pan, Chao, Reichel, John, Sejvar, James, Sheriff, Heather, Van Haren, Keith, Waldron, Paul, Watt, James, Waubant, Emmanuelle, Yagi, Shigeo, Yen, Cynthia   +17 more
core   +1 more source

Virus taxonomy: the database of the International Committee on Taxonomy of Viruses (ICTV) [PDF]

, 2017
The International Committee on Taxonomy of Viruses (ICTV) is charged with the task of developing, refining, and maintaining a universal virus taxonomy.
Dempsey, Donald M., Hendrickson, Robert Curtis, Lefkowitz, Elliot J., Orton, Richard J., Siddell, Stuart G., Smith, Donald B.   +5 more
core   +3 more sources

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

Advanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich   +10 more
wiley   +1 more source