The cis-acting replication elements define human enterovirus and rhinovirus species
Replication of picornaviruses is dependent on VPg uridylylation, which is linked to the presence of the internal cis-acting replication element (cre). Cre are located within the sequence encoding polyprotein, yet at distinct positions as demonstrated for
Gerlach, Daniel +11 more
core +1 more source
By displaying the hemagglutinin (HA) or neuraminidase (NA) proteins of influenza viruses on the surface of baculoviruses and infected insect cells, a safe and flexible pseudovirus system capable of performing cytokine analysis, serological detection and antiviral drug screening is established.
Li‐Yun Cheng +7 more
wiley +1 more source
Genomic Map of Escherichia coli and Single Nucleotide Polymorphism Markers in Colorectal Cancer
This study identified colorectal cancer‐associated SNPs in Escherichia coli using PacBio full‐genome sequencing, establishing a highly accurate SNP‐based model for non‐invasive colorectal cancer risk prediction. ABSTRACT Gut microbial single nucleotide polymorphisms (SNPs) offer stable, specific genetic markers for disease diagnosis.
Yang Xi +10 more
wiley +1 more source
Cleavage of eukaryotic initiation factor eIF5B by enterovirus 3C proteases
The enteroviruses poliovirus (PV), Coxsackie B virus (CVB) and rhinovirus (HRV) are members of Picornaviridae that inhibit host cell translation early in infection.
de Breyne, Sylvain +4 more
core +1 more source
Leucoverdazyls as Novel Potent Inhibitors of Enterovirus Replication
Enteroviruses (EV) are important pathogens causing human disease with various clinical manifestations. To date, treatment of enteroviral infections is mainly supportive since no vaccination or antiviral drugs are approved for their prevention or ...
Alexandrina S. Volobueva +9 more
doaj +1 more source
Reactive Infectious Mucocutaneous Eruption (RIME): An Australian Case Series
ABSTRACT Whilst Reactive Infectious Mucocutaneous Eruption (RIME) displays a low mortality rate, the condition results in significant morbidity and resource allocation, including prolonged hospital admission. As such, early diagnosis and optimisation of treatment is imperative.
Hamish Moore +2 more
wiley +1 more source
Studio delle possibili interazioni tra virus di derivazione umana e protisti in ambiente idrico
The ability of protists to host some bacterial pathogens such as Legionella, which have developed resistance mechanisms to escape phagocytosis and/or digestion by protists, it is well known, while some studies suggest that protists may have a possible ...
BATTISTINI, ROBERTA
core
Impact of Respiratory Viral Codetections on RSV Disease Burden in Young Children in Primary Care
ABSTRACT Background Young children with respiratory syncytial virus (RSV) often have viral coinfections. This study assessed the impact of respiratory viral codetections on RSV disease burden in children < 5 years and whether this varies by specific codetected viruses.
Levi Duijst +16 more
wiley +1 more source
Keep your child from getting and spreading enterovirus D68 [Spanish]
Keep your child from getting and spreading enterovirus D68 [Spanish]\u2022 Evite el contacto cercano con personas enfermas\u2022 C\ufabrase la nariz y la boca cuando tosa y estornude.\u2028\u2022 L\ue1vese las manos con agua y jab\uf3n.\u2028\u2022 ...
core
Structural basis for antiviral inhibition of the main protease, 3C, from human enterovirus 93
Members of the Enterovirus genus of the Picornaviridae family are abundant, with common human pathogens that belong to the rhinovirus (HRV) and enterovirus (EV) species, including diverse echo-, coxsackie- and polioviruses.
Gorbalenya, Alexander E. +29 more
core +1 more source

