Results 121 to 130 of about 64,516 (201)

Leucoverdazyls as Novel Potent Inhibitors of Enterovirus Replication

Pathogens
Enteroviruses (EV) are important pathogens causing human disease with various clinical manifestations. To date, treatment of enteroviral infections is mainly supportive since no vaccination or antiviral drugs are approved for their prevention or ...
Alexandrina S. Volobueva, Tatyana G. Fedorchenko, Galina N. Lipunova, Marina S. Valova, Valeriya A. Sbarzaglia, Anna S. Gladkikh, Olga I. Kanaeva, Natalia A. Tolstykh, Andrey N. Gorshkov, Vladimir V. Zarubaev   +9 more
doaj   +1 more source

RNA Modifications: Current Understandings and Future Perspectives

MedComm, Volume 7, Issue 5, May 2026.
Types of RNA modification. We have summarized the currently common types of RNA modifications, including ac4C, m6A, m1A, m5C, m3C, m7G, and ψ, and visually characterized their features through structural formulas. The characteristic structures are marked with a background color different from the background color.
Shiyu Xiao, Tingwen Xiang, Chuan Yang, Xiaohua Wang, Gang Huang, Fei Luo, Zhao Xie, Yueqi Chen   +7 more
wiley   +1 more source

SARS‐CoV‐2 nucleocapsid protein variants have differential RNA chaperone activity

The FEBS Journal, Volume 293, Issue 9, Page 2579-2598, May 2026.
The SARS‐CoV‐2 nucleocapsid (N) protein is not only the specific viral RNA packaging protein, but also acts as an RNA chaperone, facilitating RNA folding. We show that it facilitates RNA annealing through its RBD–IDR2–CTD region, identifying it as a functional RNA chaperone.
Sabrina Babl, Julia M. Seidel, Fabian Kugler, Elisabeth Silberhorn, Anna Ludwig, Jonas Abel, Sophia Winklbauer, Niklas Schaub, Silvia Materna‐Reichelt, Kamran Honarnejad, Nataša Stojanović Gužvić, Gernot Längst   +11 more
wiley   +1 more source

Epigenetic analyses suggest different pathways during pregnancy for development of type 1 diabetes in children with high versus low‐neutral human leukocyte antigen‐risk

Journal of Internal Medicine, Volume 299, Issue 5, Page 570-586, May 2026.
Abstract Background and objective The development of Type 1 diabetes (T1D) is shaped by genetic predisposition and epigenetic regulation. Human leukocyte antigen (HLA) risk alleles are major genetic determinants, but the epigenetic landscape in relation to disease onset remains unclear.
Shamila D. Alipoor, Angelica Ahrens, Julia Åkesson, Thomas Hillerton, Mika Gustafsson, Maria Lerm, Johnny Ludvigsson   +6 more
wiley   +1 more source

Diagnostic virology. [PDF]

, 1987
Diagnostic virology services are increasingly available and pertinent as the number of useful antiviral agents grows. In this article, current methods of diagnosis are reviewed with special emphasis on rapid procedures.
Drew, WL
core  

Regulation of viral replication by host restriction factors

Frontiers in Immunology
Viral infectious diseases, caused by numerous viruses including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), influenza A virus (IAV), enterovirus (EV), human immunodeficiency virus (HIV), hepatitis B virus (HBV), and human papillomavirus
Ying Lin, Ying Lin, Ying Lin, Yun Zhu, Yun Zhu, Ling Jing, Ling Jing, Ling Jing, Xiaobo Lei, Xiaobo Lei, Zhengde Xie, Zhengde Xie   +11 more
doaj   +1 more source

Changes in Seasonal Patterns of Pediatric Respiratory Viral Infections Before, During, and After the COVID-19 Pandemic: A Seventeen-Year Surveillance Study in the Republic of Korea

Viruses
The coronavirus disease 19 pandemic disrupted pediatric respiratory infections through non-pharmaceutical interventions and altered contact patterns. Long-term comparisons across the pandemic timeline in children remain limited.
Mi-Ru Oh, Jeong Su Han, Jae-Sik Jeon, Jae Kyung Kim   +3 more
doaj   +1 more source

Pathogenic and Molecular Characteristics of Two Isolates of HEV-B Species [PDF]

, 2012
Enteroviruses (EVs) are small non-enveloped RNA viruses forming a large group of different serotypes. EVs belong to the family Picornaviridae. The primary replication site of an enterovirus is typically the epithelium of the respiratory tract and the ...
Al-Hello, Haider
core  

Molecular evolution and circulation dynamic of human non-polio enteroviruses across Africa

International Journal of Infectious Diseases
Objectives: Human non-polio enteroviruses represent major public health concerns due to frequent outbreaks. Our study used genomic data to analyze the molecular epidemiology and circulation pattern of NPEVs in Africa, assess their inter-host transmission
Serigne Fallou MBacké NGom, NDack Ndiaye, Ousmane Kébé, NDongo Dia, Martin Faye   +4 more
doaj   +1 more source

Development of novel miRNA-based vaccines and antivirals against Enterovirus 71 [PDF]

, 2016
The Hand, Foot and Mouth Disease (HFMD) is caused by Enterovirus 71 (EV-A71) and Coxsackie viruses. Common HFMD symptoms are high fever (≥ 39oC), rashes, and ulcers but complications due to virulent EV-A71 may arise leading to cardiopulmonary failure and
Poh, Chit Laa *, Yee, Isabel Pin Tsin *
core