Results 11 to 20 of about 44,128 (189)

Human Enterovirus B: Selective Inhibition by Quinoxaline Derivatives and Bioinformatic RNA-Motif Identification as New Targets [PDF]

Pharmaceuticals, 2022
The Enterovirus genus includes many viruses that are pathogenic in humans, including Coxsackie viruses and rhinoviruses, as well as the emerging enteroviruses D68 and A71.
Silvia Madeddu, Roberta Ibba, Giuseppina Sanna, Sandra Piras, Federico Riu, Alessandra Marongiu, Annalisa Ambrosino, Paola Caria, Valentina Onnis, Gianluigi Franci, Aldo Manzin, Antonio Carta   +11 more
doaj   +3 more sources

Cellular tropism of human enterovirus D species serotypes EV‐94, EV‐70, and EV‐68 in vitro: Implications for pathogenesis [PDF]

Journal of Medical Virology, 2010
AbstractEnterovirus 94 (EV‐94) is an enterovirus serotype described recently which, together with EV‐68 and EV‐70, forms human enterovirus D species. This study investigates the seroprevalences of these three serotypes and their abilities to infect, replicate, and damage cell types considered to be essential for enterovirus‐induced diseases.
Smura T, Ylipaasto P, Klemola P, Kaijalainen S, Kyllonen L, Sordi V, PIEMONTI , LORENZO, Roivainen M.   +7 more
openaire   +5 more sources

A novel enterovirus species identified from severe diarrheal goats. [PDF]

PLoS ONE, 2017
The Enterovirus genus of the family of Picornaviridae consists of 9 species of Enteroviruses and 3 species of Rhinoviruses based on the latest virus taxonomy.
Mingyue Wang, Jia He, Haibing Lu, Yajing Liu, Yingrui Deng, Lisai Zhu, Changming Guo, Changchun Tu, Xinping Wang   +8 more
doaj   +2 more sources

Enterovirus D: A Small but Versatile Species

Microorganisms, 2021
Enteroviruses (EVs) from the D species are the causative agents of a diverse range of infectious diseases in spite of comprising only five known members. This small clade has a diverse host range and tissue tropism.
Ines Cordeiro Filipe, Mariana Soares Guedes, Evgeny M. Zdobnov, Caroline Tapparel   +3 more
doaj   +2 more sources

Enterovirus D-68 infection in human primary airway and brain organoids: no additional role for heparan sulfate binding for neurotropism

Microbiology Spectrum, 2022
EV-D68 heparan sulfate binding in HAE and brain organoid cultures.
Sridhar, Adithya, Depla, Josse, Mulder, Lance, Karelehto, Eveliina, Brouwer, Lieke, de Sá, Renata, Meijer, Adam, Evers, Melvin, van Kuppeveld, Frank, Pajkrt, Dasja, Wolthers, Katja   +10 more
openaire   +5 more sources

Activation of Host Cellular Signaling and Mechanism of Enterovirus 71 Viral Proteins Associated with Hand, Foot and Mouth Disease

Viruses, 2022
Enteroviruses are members of the Picornaviridae family consisting of human enterovirus groups A, B, C, and D as well as nonhuman enteroviruses. Human enterovirus type 71 (EV71) has emerged as a major cause of viral encephalitis, known as hand, foot, and ...
Subrat Kumar Swain, Subhasmita Panda, Basanta Pravas Sahu, Rachita Sarangi   +3 more
doaj   +2 more sources

Current Understanding of Human Enterovirus D68

Viruses, 2019
Human enterovirus D68 (EV-D68), a member of the species Enterovirus D of the Picornaviridae family, was first isolated in 1962 in the United States. EV-D68 infection was only infrequently reported until an outbreak occurred in 2014 in the US; since then,
Jing Sun, Xiao-Yi Hu, Xiao-Fang Yu
doaj   +2 more sources

Genome characterisation of enteroviruses 117 and 118: a new group within human enterovirus species C. [PDF]

PLoS ONE, 2013
The more than 120 genotypes of human enteroviruses (HEVs) reflect a wide range of evolutionary divergence, and there are 23 currently classified as human enterovirus C species (HEV-C).
Antonio Piralla, Cristina Daleno, Alessia Scala, David Greenberg, Vytautas Usonis, Nicola Principi, Fausto Baldanti, Susanna Esposito, CAP-PRI Study Group   +8 more
doaj   +3 more sources

Enterovirus serotypes in patients with central nervous system and respiratory infections in Viet Nam 1997–2010

Virology Journal, 2018
Background Enteroviruses are the most common causative agents of human illness. Enteroviruses have been associated with regional and global epidemics, recently, including with severe disease (Enterovirus A71 and D68), and are of interest as emerging ...
Nguyen Thi Thuy Chinh B’Krong, Ngo Ngoc Quang Minh, Phan Tu Qui, Tran Thi Hong Chau, Ho Dang Trung Nghia, Lien Anh Ha Do, Nguyen Ngoc Nhung, Nguyen Van Vinh Chau, Guy Thwaites, Le Van Tan, H. Rogier van Doorn, Tran Tan Thanh   +11 more
doaj   +3 more sources

Antiviral Therapeutics Discovery for Enterovirus D68.

International Journal of Infectious Diseases
Introduction: Enterovirus D68 (EV-D68) can cause a spectrum of clinical symptoms from mild respiratory symptoms to severe disease which can lead to hospitalization and even fatality in the immunocompromised, the elderly, and young children.
Prof Justin Jang H Chu
doaj   +2 more sources