Results 11 to 20 of about 45,753 (146)

Development and Assay of RNA Transcripts of Enterovirus Species A to D, Rhinovirus Species A to C, and Human Parechovirus: Assessment of Assay Sensitivity and Specificity of Real-Time Screening and Typing Methods [PDF]

Journal of Clinical Microbiology, 2012
ABSTRACT Nucleic acid amplification methods such as the PCR have had a major impact on the diagnosis of viral infections, often achieving greater sensitivities and shorter turnaround times than conventional assays and an ability to detect viruses refractory to conventional isolation methods.
McLeish, N. J., Witteveldt, J., Clasper, L., McIntyre, C., Leitch, E. C. M., Hardie, A., Bennett, S., Gunson, R., Carman, W. F., Feeney, S. A., Coyle, P. V., Vipond, B., Muir, P., Benschop, K., Wolthers, K., Waris, M., Osterback, R., Johannessen, I., Templeton, K., Harvala, H., Simmonds, P.   +20 more
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Selective Serotonin Reuptake Inhibitor Fluoxetine Inhibits Replication of Human Enteroviruses B and D by Targeting Viral Protein 2C [PDF]

Antimicrobial Agents and Chemotherapy, 2013
ABSTRACT Although the genus Enterovirus contains many important human pathogens, there is no licensed drug for either the treatment or the prophylaxis of enterovirus infections. We report that fluoxetine (Prozac)—a selective serotonin reuptake inhibitor—inhibits the replication of human enterovirus B (HEV ...
Ulferts, R., van der Linden, L., Thibaut, H.J., Lanke, K.H.W., Leyssen, P., Coutard, B., De Palma, A.M., Canard, B., Neyts, J., van Kuppeveld, F.J.M., van Kuppeveld, F.J.M.   +10 more
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Enterovirus 94, a proposed new serotype in human enterovirus species D

Journal of General Virology, 2007
The genus Enterovirus (family Picornaviridae) contains five species with strains isolated from humans: Human enterovirus A (HEV-A), HEV-B, HEV-C, HEV-D and Poliovirus. In this study, a proposed new serotype of HEV-D was characterized. Four virus strains were isolated from sewage in Egypt and one strain from acute flaccid paralysis cases in the ...
Teemu P, Smura, Nina, Junttila, Soile, Blomqvist, Helene, Norder, Svetlana, Kaijalainen, Anja, Paananen, Lars O, Magnius, Tapani, Hovi, Merja, Roivainen   +8 more
openaire   +2 more sources

Retrospective Surveillance of Wastewater To Examine Seasonal Dynamics of Enterovirus Infections

mSphere, 2017
Enteroviruses are RNA viruses that are responsible for both mild gastroenteritis and mild respiratory illnesses as well as debilitating diseases such as meningitis and myocarditis.
Nichole E. Brinkman, G. Shay Fout, Scott P. Keely   +2 more
doaj   +1 more source

Computational Approach for Predicting Common Epitopes in the VP1 Structural Protein of Enterovirus Serotypes EV-D68, EV-D70, and EV-A71

Journal of Pure and Applied Microbiology, 2021
The three human Enterovirus serotypes D-68, D-70, and A-71, are common pathogens that are transmitted by fecal-oral and aerosol routes. These positive RNA viruses were known to exhibit high levels of genetic diversity and variability.
Rihabe Boussettine, Yassine Kasmi, Najwa Hassou, Hlima Bessi, Moulay Mustapha Ennaji   +4 more
doaj   +1 more source

Enterovirus 68 among Children with Severe Acute Respiratory Infection, the Philippines

Emerging Infectious Diseases, 2011
Enterovirus 68 (EV68) is a rare enterovirus associated with respiratory illness that, unlike other enteroviruses, has been identified only from respiratory specimens. We identified EV68 from respiratory specimens of children hospitalized with a diagnosis
Tadatsugu Imamura, Naoko Fuji, Akira Suzuki, Raita Tamaki, Mariko Saito, Rapunzel Aniceto, Hazel Galang, Lydia Sombrero, Soccoro Lupisan, Hitoshi Oshitani   +9 more
doaj   +1 more source

Metabolic reprogramming as a novel therapeutic target for Coxsackievirus B3

Animal Cells and Systems, 2022
Coxsackievirus B3 (CVB3) is a single-stranded RNA virus that belongs to the Enterovirus genus. CVB3 is a human pathogen associated with serious conditions such as myocarditis, dilated cardiomyopathy, and pancreatitis.
Myeong Uk Kuk, Yun Ji Ga, Ye Jin Kim, Ji Yun Park, Eun Seon Song, Haneur Lee, Yun Haeng Lee, Gahyun Ko, Jae Kwang Kim, Jung-Yong Yeh, Hyung Wook Kwon, Youngjoo Byun, Joon Tae Park   +12 more
doaj   +1 more source

Susceptibility and cytokine responses of human neuronal cells to multiple circulating EV-A71 genotypes in India

Scientific Reports, 2021
Enterovirus-A71 (EV-A71) associated Hand, foot and mouth disease (HFMD) is a highly contagious viral infection affecting children in Asia–Pacific region and has become a major threat to public health.
Madhu Chhanda Mohanty, Swapnil Yashavant Varose, Vinay Kumar Saxena   +2 more
doaj   +1 more source

Enterovirus serotypes in patients with central nervous system and respiratory infections in Viet Nam 1997–2010

Virology Journal, 2018
Background Enteroviruses are the most common causative agents of human illness. Enteroviruses have been associated with regional and global epidemics, recently, including with severe disease (Enterovirus A71 and D68), and are of interest as emerging ...
Nguyen Thi Thuy Chinh B’Krong, Ngo Ngoc Quang Minh, Phan Tu Qui, Tran Thi Hong Chau, Ho Dang Trung Nghia, Lien Anh Ha Do, Nguyen Ngoc Nhung, Nguyen Van Vinh Chau, Guy Thwaites, Le Van Tan, H. Rogier van Doorn, Tran Tan Thanh   +11 more
doaj   +1 more source

Whole Genome Sequencing of Enteroviruses Species A to D by High-Throughput Sequencing: Application for Viral Mixtures

Frontiers in Microbiology, 2018
Human enteroviruses (EV) consist of more than 100 serotypes classified within four species for enteroviruses (EV-A to -D) and three species for rhinoviruses, which have been implicated in a variety of human illnesses. Being able to simultaneously amplify
Marie-Line Joffret, Marie-Line Joffret, Marie-Line Joffret, Patsy M. Polston, Patsy M. Polston, Richter Razafindratsimandresy, Maël Bessaud, Maël Bessaud, Maël Bessaud, Jean-Michel Heraud, Francis Delpeyroux, Francis Delpeyroux, Francis Delpeyroux   +12 more
doaj   +1 more source