Results 61 to 70 of about 3,707 (163)

Achilles tenocytes from diabetic and non diabetic donors exposed to hyperglycemia respond differentially to inflammatory stimuli and stretch

open access: yesJournal of Anatomy, EarlyView.
Scheme depicting the experimental set up of the study. Achilles tendons and tenocytes were isolated from heterozygous (fa/+, non diabetic: non DMT2) and homozygous (fa/fa, diabetic: DMT2) Zucker Diabetic Fatty (ZDF) rats. Tendon degeneration, collagen type 1 alpha 1 chain (COL1A1) and alpha smooth muscle actin (αSMA) expression was determined in rat ...
Nils Fleischmann   +8 more
wiley   +1 more source

Development and validation of a novel approach for quantifying dimensions of the lateral ligaments in human ankle dissections

open access: yesJournal of Anatomy, EarlyView.
Traditional measurement techniques in cadaveric dissection fail to account for the changes in soft tissue length during joint movement. We have developed a new, simple method to obtain more accurate measurements of ligament length and validated using the lateral ankle ligaments group.
Sophie J. Mok   +2 more
wiley   +1 more source

Transcriptome profiling of tendon fibroblasts at the onset of embryonic muscle contraction reveals novel force-responsive genes

open access: yeseLife
Mechanical forces play a critical role in tendon development and function, influencing cell behavior through mechanotransduction signaling pathways and subsequent extracellular matrix (ECM) remodeling.
Pavan K Nayak   +2 more
doaj   +1 more source

Diffuse idiopathic skeletal hyperostosis - a case report

open access: yesNational Journal of Clinical Anatomy, 2013
The case reported here is an incidental finding of a specimen of lower three lumbar vertebrae with sacrum. It displayed ossification of anterolateral aspect of lower three lumbar vertebrae with sparing of intervertebral disc space.
Nitin R Mudiraj, Manisha R Dhobale
doaj   +1 more source

Collagen organisation in the fibrous joint capsules in the digits of the human hand

open access: yesJournal of Anatomy, EarlyView.
The function of the finger joints is important for daily life. In this review of the literature, we consider the role of collagen and its organization within the fibrous finger joint capsules of the interphalangeal (IP) joints and investigate the relationships between collagen orientation and joint function. Abstract Normal function of the hand and, in
Fiona R. Saunders   +3 more
wiley   +1 more source

On the heterogeneity of the femoral enthesis of the human ACL: microscopic anatomy and clinical implications

open access: yesJournal of Experimental Orthopaedics, 2016
Background Most ruptures of the native anterior cruciate ligament (ACL) and ACL graft occur at, or near, the femoral enthesis, with the posterolateral fibers of the native ligament being especially vulnerable during pivot landings.
Mélanie L. Beaulieu   +4 more
doaj   +1 more source

Growth and mechanobiology of the tendon-bone enthesis

open access: yesSeminars in Cell & Developmental Biology, 2022
Tendons are cable-like connective tissues that transfer both active and passive forces generated by skeletal muscle to bone. In the mature skeleton, the tendon-bone enthesis is an interfacial zone of transitional tissue located between two mechanically dissimilar tissues: compliant, fibrous tendon to rigid, dense mineralized bone.
openaire   +2 more sources

Intraarticular Ligament Degeneration Is Interrelated with Cartilage and Bone Destruction in Osteoarthritis

open access: yesCells, 2019
Osteoarthritis (OA) induces inflammation and degeneration of all joint components including cartilage, joint capsule, bone and bone marrow, and ligaments.
Gundula Schulze-Tanzil
doaj   +1 more source

Development of the human Achilles tendon enthesis organ

open access: yesJournal of Anatomy, 2008
AbstractThe attachment of the Achilles tendon is part of an ‘enthesis organ’ that reduces stress concentration at the hard–soft tissue interface. The organ also includes opposing sesamoid and periosteal fibrocartilages, a bursa and Kager's fat pad. In addition, the deep crural and plantar fasciae contribute to Achilles stress dissipation and could also
H M, Shaw   +5 more
openaire   +3 more sources

Do plantar calcaneal spurs make the plantar aponeurosis enthesis stronger? A biomechanical analysis

open access: yesJournal of Anatomy, EarlyView.
Novel testing set up for determining enthesial avulsion parameters. Donor calcanei were dissected to isolate the central band of the plantar fascia, and mounted in a custom 3D‐printed rig (Fig A, B, C) for uniaxial tensile testing of the plantar fascia enthesis (Fig D). This study demonstrated no significant differences in the avulsion parameters, Fmax
Joanna Tomlinson   +2 more
wiley   +1 more source

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