Results 51 to 60 of about 5,862 (206)

New perspectives in enthesis ultrasound: validation of enthesis fibrocartilage

International Journal of Clinical Rheumatology, 2011
Evaluation of: Aydin SZ, Bas E, Basci O et al.: Validation of ultrasound imaging for Achilles entheseal fibrocartilage in bovines and description of changes in humans with spondyloarthritis. Ann. Rheum. Dis. 69(12), 2165–2168 (2010). Enthesitis, the hallmark of spondyloarthritis is underestimated in clinical practice and improving the knowledge of ...
openaire   +1 more source

Software for Predicting Enthesis Strength, Toughness, and Stiffness

, 2021
This file contains software to reproduce simulations in Golman, et al., "Enthesis strength, toughness, and stiffness: an image-based model comparing tendon insertions with varying bony attachment geometries," to appear in Journal of the Royal Society ...
Stavros Thomopoulos, Mikhail Golman, Victor Birman, Guy Genin   +3 more
core   +1 more source

A Programmable Braided Silk‐Glass Fiber Ligament Promoting Rapid Motoric Recovery

Advanced Science, EarlyView.
A scalable three‐dimensional braiding strategy integrates silk and glass fibers into customizable artificial ligaments with programmable “J‐shaped” nonlinear mechanics. The silk‐rich architecture supports osseoligamentous integration, while glass fibers provide mechanical reinforcement and biomimetic mineralization cues, enabling strain‐adaptive load ...
Changbo Lu, Daming Liu, Haoxin Zhang, Zhiwei Qiao, Qiuming Gao, Jia Meng, Hongyin Yue, Songkai Li, Shuo Zhang, Tao Yuan, Yun Xue, Hui Jiang, Zhenguo Liu, Yibo Wang, Nirong Bao, Yuli Chen, Xiaojiang Yang   +16 more
wiley   +1 more source

Machine Learning‐Enabled Field Prediction and Inverse Design of Functionally Graded Materials Inspired by Tendon–Bone Enthesis

Advanced Intelligent Systems, EarlyView.
A mechanics‐informed machine learning framework enables mechanics field prediction and inverse design of tendon–bone enthesis‐inspired functionally graded materials that reduce stress concentration and failure risk. By coupling multiscale finite element modeling, convolutional field prediction, and kernel‐based inverse design, the study uncovers ...
Zhangke Yang, Zhaoxu Meng
wiley   +1 more source

Tissue Engineering for the Insertions of Tendons and Ligaments: An Overview of Electrospun Biomaterials and Structures

Frontiers in Bioengineering and Biotechnology, 2021
The musculoskeletal system is composed by hard and soft tissue. These tissues are characterized by a wide range of mechanical properties that cause a progressive transition from one to the other.
Alberto Sensini, Gabriele Massafra, Carlo Gotti, Andrea Zucchelli, Andrea Zucchelli, Luca Cristofolini, Luca Cristofolini   +6 more
doaj   +1 more source

Toughening mechanisms for the attachment of architectured materials: The mechanics of the tendon enthesis [PDF]

, 2021
Use of load-bearing materials whose functionality arises from architectured microstructures, so called architectured materials, has been hindered by the challenge of connecting them.
Golman, Mikhail
core   +1 more source

Decoding the mechanical characteristics of the human anterior cruciate ligament entheses through graduated mineralization interfaces

Nature Communications
The anterior cruciate ligament is anchored to the femur and tibia via specialized interfaces known as entheses. These play a critical role in ligament homeostasis and joint stability by transferring forces, varying in magnitude and direction between ...
Jinghua Fang, Xiaozhao Wang, Huinan Lai, Wenyue Li, Xudong Yao, Zongyou Pan, Renwei Mao, Yiyang Yan, Chang Xie, Junxin Lin, Wei Sun, Rui Li, Jiajie Wang, Jiacheng Dai, Kaiwang Xu, Xinning Yu, Tengjing Xu, Wangping Duan, Jin Qian, Hongwei Ouyang, Xuesong Dai   +20 more
doaj   +1 more source

Bi-fated tendon-to-bone attachment cells are regulated by shared enhancers and KLF transcription factors

eLife, 2021
The mechanical challenge of attaching elastic tendons to stiff bones is solved by the formation of a unique transitional tissue. Here, we show that murine tendon-to-bone attachment cells are bi-fated, activating a mixture of chondrocyte and tenocyte ...
Shiri Kult, Tsviya Olender, Marco Osterwalder, Svetalana Markman, Dena Leshkowitz, Sharon Krief, Ronnie Blecher-Gonen, Shani Ben-Moshe, Lydia Farack, Hadas Keren-Shaul, Tomer-Meir Salame, Terence D Capellini, Shalev Itzkovitz, Ido Amit, Axel Visel, Elazar Zelzer   +15 more
doaj   +1 more source

Anatomy and variation in the paraphyletic Mosasaurus lemonnieri assemblage from the Craie phosphatée de ciply, Belgium

The Anatomical Record, EarlyView.
Abstract Nineteenth century excavations of the Ciply‐Malogne Phosphatic Chalk Formation in Hainaut, Belgium, yielded over 50 partial mosasaur skeletons, the majority of which were referred to the species Mosasaurus lemonnieri Dollo, 1889. In the years since, this taxon has experienced a complicated taxonomic history, and its exceptional hypodigm has ...
Henry S. Sharpe, Hallie P. Street‐Sampson, Takuya Konishi, Michael W. Caldwell   +3 more
wiley   +1 more source

IL-17A and TNF Modulate Normal Human Spinal Entheseal Bone and Soft Tissue Mesenchymal Stem Cell Osteogenesis, Adipogenesis, and Stromal Function

Cells, 2021
Objective: The spondylarthritides (SpA) are intimately linked to new bone formation and IL-17A and TNF pathways. We investigated spinal soft tissue and bone mesenchymal stem cell (MSC) responses to IL-17A and TNF, including their osteogenesis ...
Tobias Russell, Abdulla Watad, Charlie Bridgewood, Hannah Rowe, Almas Khan, Abhay Rao, Peter Loughenbury, Peter Millner, Robert Dunsmuir, Richard Cuthbert, Ala Altaie, Elena Jones, Dennis McGonagle   +12 more
doaj   +1 more source