Results 71 to 80 of about 26,191 (209)

Accurate macroscale modelling of spatial dynamics in multiple dimensions

, 2012
Developments in dynamical systems theory provides new support for the macroscale modelling of pdes and other microscale systems such as Lattice Boltzmann, Monte Carlo or Molecular Dynamics simulators.
Bunder, J. E., MacKenzie, Tony, Roberts, A. J.   +2 more
core  

Artificial intelligence strategies for predicting kinase inhibitor resistance: A comprehensive review of methods, challenges, and future perspectives

Journal of Intelligent Medicine, EarlyView.
Abstract Kinase inhibitors are essential in targeted cancer therapy, yet resistance often emerges through secondary mutations, activation of compensatory signaling pathways, or drug‐efflux mechanisms. Artificial intelligence (AI) provides a workflow‐based strategy rather than a list of unrelated tools for predicting and addressing kinase‐inhibitor ...
Faris Hassan, Mohanad Ali Deifallah, Alaa Zaghloul, Rania Elgohary   +3 more
wiley   +1 more source

Coping Practices of Small‐ and Medium‐Sized Enterprises Facing Power Asymmetry in Digital Platform Business

Strategic Change, EarlyView.
ABSTRACT Digital platform (DP) enterprises have risen to the top of the global economy by inverting traditional business models. They earn money through matchmaking, transaction facilitation, and efficient orchestration of other stakeholders' resources.
Lukas R. G. Fitz, Jochen Scheeg
wiley   +1 more source

Clinical Efficacy and Safety of Topical Roflumilast in Psoriasis: An Updated Systematic Review and Meta‐Analysis of Randomized Controlled Trials

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Traditional first‐line topical treatments for plaque psoriasis, particularly corticosteroids and vitamin D analogs, frequently have only limited efficacy for long‐term use, and present difficulties with safety and adherence. Objectives In this systematic review and meta‐analysis of randomized controlled trials (RCTs), we assessed ...
Aimal A. Khattak, Ahmed Javed, Ummi Aiman Rahman, Rumaisa Riaz, Zeeshan Imtiaz, Hassan A. Mirza, Farman U. Khan, Muhid Khattak, Fatima Javid, Abdul Moiz Khan, Adeline L. Roy, Bibek Shrestha   +11 more
wiley   +1 more source

New Biologic and Small Molecule Therapies for Hidradenitis Suppurativa

JEADV Clinical Practice, EarlyView.
ABSTRACT Hidradenitis suppurativa (HS) is an inflammatory skin disease that has historically been underdiagnosed and, until recently, under‐researched. Furthermore, the pathophysiology of HS is complex, and not fully understood. Just three biologic medications—adalimumab (anti‐TNF‐α), secukinumab (anti‐IL17A) and bimekizumab (anti‐IL17A/F) are licensed
Emily Pender, Rosalind Hughes, Brian Kirby   +2 more
wiley   +1 more source

The description of entire solutions of complex PDEs and PDDEs [PDF]

Zhao Jun Wu, Hong Yan Xu, Zu Xing Xuan
openalex   +1 more source

Using physics‐informed neural networks to quantify submarine groundwater discharge under high‐frequency tidal dynamics using heat as a tracer

Limnology and Oceanography: Methods, EarlyView.
Abstract Estimating exchange rates of submarine groundwater discharge (SGD) at high temporal resolution over extended periods remains challenging, particularly when using heat as a tracer in highly dynamic environments such as tidal systems. Currently available heat transport models struggle to accurately quantify SGD exchange rates in these settings ...
S. Frei, M. U. Munir, A. M. Seiverth, B. S. Gilfedder   +3 more
wiley   +1 more source

Unveiling New Perspectives on the Hirota–Maccari System With Multiplicative White Noise

Mathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT In this study, we delve into the stochastic Hirota–Maccari system, which is subjected to multiplicative noise according to the Itô sense. The stochastic Hirota–Maccari system is significant for its ability to accurately model how stochastic affects nonlinear wave propagation, providing valuable insights into complex systems like fluid dynamics
Mohamed E. M. Alngar, Khaled A. Gepreel, Reham M. A. Shohib, Yakup Yildirim   +3 more
wiley   +1 more source

Asymptotic Analysis of the Static Bidomain Model for Pulsed Field Cardiac Ablation

Mathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT Cardiac arrhythmias are caused by faulty electrical signals in the heart, which lead to chaotic wave propagation and impaired cardiac function. This work focuses on a non‐thermal ablation technique based on electroporation (EP), a promising method for treating arrhythmias, called pulsed field ablation (PFA).
Annabelle Collin, Simone Nati Poltri, Clair Poignard   +2 more
wiley   +1 more source

C∞$$ {C}^{\infty } $$‐Structures for Liénard Equations and New Exact Solutions to a Class of Klein–Gordon Equations

Mathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT Liénard equations are analyzed using the recent theory of 𝒞∞‐structures. For each Liénard equation, a 𝒞∞‐structure is determined by using a Lie point symmetry and a 𝒞∞‐symmetry. Based on this approach, a novel method for integrating these equations is proposed, which consists in solving sequentially two completely integrable Pfaffian equations.
Beltrán de la Flor, Adrián Ruiz, Concepción Muriel   +2 more
wiley   +1 more source