Results 1 to 10 of about 39,445 (247)

Cortisol treatment impairs path integration and alters grid-like representations in the male human entorhinal cortex. [PDF]

PLoS Biology
Acute stress triggers the release of cortisol, which broadly affects cognitive processes. Path integration, a specific navigational process, relies heavily on grid cells in the entorhinal cortex.
Osman Akan, Varnan Chandreswaran, Henry D Soldan, Anne Bierbrauer, Nikolai Axmacher, Oliver T Wolf, Christian J Merz   +6 more
doaj   +2 more sources

Entorhinal cortex layer III Adgrl2 expression controls topographical circuit connectivity required for sequence learning [PDF]

Translational Psychiatry
The entorhinal cortex and hippocampus are interconnected brain regions required for episodic learning and memory. For this functional encoding, correct assembly of specific synaptic connections across this circuit is critical during development. To guide
Jordan D. Donohue, Crisylle Blanton, Anna Chen, Amna Ahmad, Elizabeth D. Liu, Lisette Saab, Rajbir Kaur, Woojin Yang, Garret R. Anderson   +8 more
doaj   +2 more sources

Mental navigation in the primate entorhinal cortex. [PDF]

Nature
AbstractA cognitive map is a suitably structured representation that enables novel computations using previous experience; for example, planning a new route in a familiar space1. Work in mammals has found direct evidence for such representations in the presence of exogenous sensory inputs in both spatial2,3 and non-spatial domains4–10. Here we tested a
Neupane S, Fiete I, Jazayeri M.
europepmc   +3 more sources

Acute stress modulates hippocampal to entorhinal cortex communication

Frontiers in Cellular Neuroscience, 2023
Feed-forward inhibition is vital in the transfer and processing of synaptic information within the hippocampal–entorhinal loop by controlling the strength and direction of excitation flow between different neuronal populations and individual neurons ...
Azat Nasretdinov, David Jappy, David Jappy, Alina Vazetdinova, Alina Vazetdinova, Fliza Valiullina-Rakhmatullina, Fliza Valiullina-Rakhmatullina, Andrei Rozov, Andrei Rozov   +8 more
doaj   +1 more source

Crossed Entorhino-Dentate Projections Form and Terminate With Correct Layer-Specificity in Organotypic Slice Cultures of the Mouse Hippocampus

Frontiers in Neuroanatomy, 2021
The entorhino-dentate projection, i.e., the perforant pathway, terminates in a highly ordered and laminated fashion in the rodent dentate gyrus (DG): fibers arising from the medial entorhinal cortex (MEC) terminate in the middle molecular layer, whereas ...
Lars Hildebrandt-Einfeldt, Kenrick Yap, Mandy H. Paul, Carolin Stoffer, Nadine Zahn, Alexander Drakew, Maximilian Lenz, Andreas Vlachos, Andreas Vlachos, Andreas Vlachos, Thomas Deller   +10 more
doaj   +1 more source

Grid alignment in entorhinal cortex [PDF]

Biological Cybernetics, 2012
The spatial responses of many of the cells recorded in all layers of rodent medial entorhinal cortex (mEC) show a triangular grid pattern, and once established might be based in part on path-integration mechanisms. Grid axes are tightly aligned across simultaneously recorded units.
SI, BAILU, Kropff, Emilio, Treves, Alessandro   +2 more
openaire   +4 more sources

Entorhinal cortex and parahippocampus volume reductions impact olfactory decline in aged subjects

Brain and Behavior, 2021
Introduction Pathological abnormalities first appear in the medial temporal regions including entorhinal cortex and parahippocampus in patients with Alzheimer's disease.
Natsuko Iizuka, Yuri Masaoka, Satomi Kubota, Haruko Sugiyama, Masaki Yoshida, Akira Yoshikawa, Nobuyoshi Koiwa, Motoyasu Honma, Keiko Watanabe, Shotaro Kamijo, Sawa Kamimura, Masahiro Ida, Kenjiro Ono, Masahiko Izumizaki   +13 more
doaj   +1 more source

Entorhinal and Transentorhinal Atrophy in Preclinical Alzheimer's Disease

Frontiers in Neuroscience, 2020
This study examines the atrophy patterns in the entorhinal and transentorhinal cortices of subjects that converted from normal cognition to mild cognitive impairment.
Sue Kulason, Sue Kulason, Sue Kulason, Eileen Xu, Daniel J. Tward, Daniel J. Tward, Arnold Bakker, Arnold Bakker, Marilyn Albert, Laurent Younes, Laurent Younes, Laurent Younes, Michael I. Miller, Michael I. Miller, Michael I. Miller, Michael I. Miller   +15 more
doaj   +1 more source

Effects of acetylcholine on neuronal properties in entorhinal cortex

Frontiers in Behavioral Neuroscience, 2012
The entorhinal cortex receives prominent cholinergic innervation from the medial septum and the vertical limb of the diagonal band of Broca (MSDB). To understand how cholinergic neurotransmission can modulate behavior, research has been directed towards ...
James G Heys, Nathan W Schultheiss, Christopher F Shay, Yusuke eTsuno, Michael E Hasselmo   +4 more
doaj   +1 more source

Electrical Stimulation of the Lateral Entorhinal Cortex Causes a Frequency-Specific BOLD Response Pattern in the Rat Brain

Frontiers in Neuroscience, 2019
Although deep brain stimulation of the entorhinal cortex has recently shown promise in the treatment of early forms of cognitive decline, the underlying neurophysiological processes remain elusive.
Karla Krautwald, Liv Mahnke, Frank Angenstein, Frank Angenstein, Frank Angenstein   +4 more
doaj   +1 more source