Results 111 to 120 of about 72,560 (254)
Abstract Objective Epilepsy surgery is an effective treatment option for patients with medically refractory epilepsy due to mild malformation of cortical development with oligodendroglial hyperplasia (MOGHE). The success of surgery depends on the accurate localization of the epileptogenic zone, which can be challenging due to the subtle imaging ...
Jean Khoury +7 more
wiley +1 more source
Postsynaptic Signals Mediating Induction of Long-Term Synaptic Depression in the Entorhinal Cortex
The entorhinal cortex receives a large projection from the piriform cortex, and synaptic plasticity in this pathway may affect olfactory processing. In vitro whole cell recordings have been used here to investigate postsynaptic signalling mechanisms that
Saïd Kourrich +3 more
doaj +1 more source
Structural development and dorsoventral maturation of the medial entorhinal cortex
We investigated the structural development of superficial-layers of medial entorhinal cortex and parasubiculum in rats. The grid-layout and cholinergic-innervation of calbindin-positive pyramidal-cells in layer-2 emerged around birth while reelin ...
Saikat Ray, Michael Brecht
doaj +1 more source
The spectro-contextual encoding and retrieval theory of episodic memory. [PDF]
The spectral fingerprint hypothesis, which posits that different frequencies of oscillations underlie different cognitive operations, provides one account for how interactions between brain regions support perceptual and attentive processes (Siegel etal.,
Ekstrom, Arne D, Watrous, Andrew J
core +1 more source
Amygdala enlargement associated with remote epileptogenic lesions
Abstract Objective To determine the prevalence and possible causes of amygdala enlargement in patients with drug‐resistant temporal lobe epilepsy. Methods Patients were retrospectively identified via a radiology information system and a large language model.
Horst Urbach +5 more
wiley +1 more source
What grid cells convey about rat location [PDF]
We characterize the relationship between the simultaneously recorded quantities of rodent grid cell firing and the position of the rat. The formalization reveals various properties of grid cell activity when considered as a neural code for representing ...
Brookings, Ted +2 more
core
Colocalization of neurons in optical coherence microscopy and Nissl-stained histology in Brodmann’s area 32 and area 21 [PDF]
Published in final edited form as: Brain Struct Funct. 2019 January ; 224(1): 351–362. doi:10.1007/s00429-018-1777-z.Optical coherence tomography is an optical technique that uses backscattered light to highlight intrinsic structure, and when applied to
Augustinack, Jean C. +7 more
core +1 more source
Background Alzheimer's disease is a complex neurodegenerative disorder characterized pathologically by a temporal and spatial progression of beta-amyloid (Aβ) deposition, neurofibrillary tangle formation, and synaptic degeneration. Inflammatory processes
LaFerla Frank M +5 more
doaj +1 more source
Abstract Spatial memory, the aspect of memory involving encoding and retrieval of information regarding one's environment and spatial orientation, is a complex biological function incorporating multiple neuronal networks. Hippocampus‐dependent spatial memory is not innate and emerges during development in both humans and rodents.
Gregory L. Holmes
wiley +1 more source
The medial entorhinal cortex is necessary for temporal organization of hippocampal neuronal activity. [PDF]
The superficial layers of the medial entorhinal cortex (MEC) are a major input to the hippocampus. The high proportion of spatially modulated cells, including grid cells and border cells, in these layers suggests that MEC inputs are critical for the ...
Boublil, Brittney L +8 more
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