Results 91 to 100 of about 73,004 (270)
A mouse model of early sporadic tau pathology induces neurogenic plasticity in the hippocampus.
PLoS ONEAlzheimer's disease varies by sex but is broadly characterized by widespread neurodegeneration and the accumulation of insoluble amyloid plaques and neurofibrillary tangles.
Alyssa M Ash +7 more
doaj +1 more source
What is the functional role of adult neurogenesis in the hippocampus? [PDF]
, 2004 The dentate gyrus is part of the hippocampal memory system and special in that it generates new neurons throughout life. Here we discuss the question of what the functional role of these new neurons might be.
Kempermann, Gerd +2 more
core +1 more source
Neuroanatomical spread of amyloid β and tau in Alzheimer's disease: implications for primary prevention. [PDF]
, 2020 With recent advances in our understanding of the continuous pathophysiological changes that begin many years prior to symptom onset, it is now apparent that Alzheimer's disease cannot be adequately described by discrete clinical stages, but should also ...
Aisen, Paul S +4 more
core +1 more source
Human Conscious Experience is Four-Dimensional and has a Neural Correlate Modeled by Einstein's Special Theory of Relativity [PDF]
, 2016 In humans, knowing the world occurs through spatial-temporal experiences and interpretations. Conscious experience is the direct observation of conscious events. It makes up the content of consciousness.
Sieb, Richard
core +1 more source
Epilepsia Open, EarlyView.Abstract Spatial memory, the aspect of memory involving encoding and retrieval of information regarding one's environment and spatial orientation, is a complex biological function incorporating multiple neuronal networks. Hippocampus‐dependent spatial memory is not innate and emerges during development in both humans and rodents.
Gregory L. Holmes
wiley +1 more source
Student's Journal of Health Research AfricaBackground Mild Cognitive Impairment (MCI) is an intermediate stage between normal cognitive aging and dementia, characterized by subtle cognitive decline.
Karishma Khushalrao Surpam
doaj +1 more source
Cell Reports, 2019 Summary: The current model of the organization of the medial temporal lobe (MTL) episodic memory system assumes that two functionally different “where” and “what” pathways enter MTL as parallel parahippocampal cortex (PHC)-medial entorhinal cortex (MEC ...
Thanh P. Doan +4 more
doaj +1 more source
Differential medial temporal lobe morphometric predictors of item- and relational-encoded memories in healthy individuals and in individuals with mild cognitive impairment and Alzheimer's disease. [PDF]
, 2017 INTRODUCTION:Episodic memory processes are supported by different subregions of the medial temporal lobe (MTL). In contrast to a unitary model of memory recognition supported solely by the hippocampus, a current model suggests that item encoding engages ...
Conejero-Goldberg, Concepcion +7 more
core +1 more source
Artificial intelligence in preclinical epilepsy research: Current state, potential, and challenges
Epilepsia Open, EarlyView.Abstract Preclinical translational epilepsy research uses animal models to better understand the mechanisms underlying epilepsy and its comorbidities, as well as to analyze and develop potential treatments that may mitigate this neurological disorder and its associated conditions. Artificial intelligence (AI) has emerged as a transformative tool across
Jesús Servando Medel‐Matus +7 more
wiley +1 more source
Brazilian Journal of Medical and Biological Research, 2005 We studied the effects of infusion of nerve growth factor (NGF) into the hippocampus and entorhinal cortex of male Wistar rats (250-300 g, N = 11-13 per group) on inhibitory avoidance retention.
Walz R. +5 more
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