Results 81 to 90 of about 73,004 (270)

Effect of reward on electrophysiological signatures of grid cell population activity in human spatial navigation

open access: yesScientific Reports, 2021
The regular equilateral triangular periodic firing pattern of grid cells in the entorhinal cortex is considered a regular metric for the spatial world, and the grid-like representation correlates with hexadirectional modulation of theta (4–8 Hz) power in
Wenjing Wang, Wenxu Wang
doaj   +1 more source

Deep characterization of refractory epilepsy due to mild malformation of cortical development with oligodendroglial hyperplasia (MOGHE) and insights into the role of invasive monitoring

open access: yesEpilepsia, EarlyView.
Abstract Objective Epilepsy surgery is an effective treatment option for patients with medically refractory epilepsy due to mild malformation of cortical development with oligodendroglial hyperplasia (MOGHE). The success of surgery depends on the accurate localization of the epileptogenic zone, which can be challenging due to the subtle imaging ...
Jean Khoury   +7 more
wiley   +1 more source

Monoclonal Antibody Identification of Subpopulations of Cerebral Cortical Neurons Affected in Alzheimer disease [PDF]

open access: yes, 1987
Neuronal degeneration is one of the hallmarks of Alzheimer disease (AD). Given the paucity of molecular markers available for the identification of neuronal subtypes, the specificity of neuronal loss within the cerebral cortex has been difficult to ...
Blanks, Janet C.   +4 more
core  

Individual differences in human path integration abilities correlate with gray matter volume in retrosplenial cortex, hippocampus, and medial prefrontal cortex [PDF]

open access: yes, 2017
Humans differ in their individual navigational abilities. These individual differences may exist in part because successful navigation relies on several disparate abilities, which rely on different brain structures.
Aselcioglu, Irem   +4 more
core   +1 more source

Amygdala enlargement associated with remote epileptogenic lesions

open access: yesEpilepsia, EarlyView.
Abstract Objective To determine the prevalence and possible causes of amygdala enlargement in patients with drug‐resistant temporal lobe epilepsy. Methods Patients were retrospectively identified via a radiology information system and a large language model.
Horst Urbach   +5 more
wiley   +1 more source

Beta Oscillations and Hippocampal Place Cell Learning during Exploration of Novel Environments [PDF]

open access: yes, 2008
Berke et al. (2008) reported that beta oscillations occur during the learning of hippocampal place cell receptive fields in novel environments. Place cell selectivity can develop within seconds to minutes, and can remain stable for months. Paradoxically,
Grossberg, Stephen
core   +1 more source

Structural MRI Correlates of Episodic Memory Processes in Parkinson's Disease Without Mild Cognitive Impairment. [PDF]

open access: yes, 2015
BackgroundChanges in episodic memory are common early in Parkinson's disease (PD) and may be a risk factor for future cognitive decline. Although medial temporal lobe (MTL) memory and frontostriatal (FS) executive systems are thought to play different ...
Filoteo, J Vincent   +3 more
core   +2 more sources

Shared rhythmic subcortical GABAergic input to the entorhinal cortex and presubiculum

open access: yeseLife, 2018
Rhythmic theta frequency (~5–12 Hz) oscillations coordinate neuronal synchrony and higher frequency oscillations across the cortex. Spatial navigation and context-dependent episodic memories are represented in several interconnected regions including the
Tim James Viney   +5 more
doaj   +1 more source

Functional subregions of the human entorhinal cortex

open access: yeseLife, 2015
The entorhinal cortex (EC) is the primary site of interactions between the neocortex and hippocampus. Studies in rodents and nonhuman primates suggest that EC can be divided into subregions that connect differentially with perirhinal cortex (PRC) vs parahippocampal cortex (PHC) and with hippocampal subfields along the proximo-distal axis. Here, we used
Anne Maass   +4 more
openaire   +6 more sources

Unique deficits in place coding across subfields of the hippocampus in a mouse model of temporal lobe epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Memory problems are comorbid with temporal lobe epilepsy (TLE). Animal models of TLE reveal impairments in spatial firing fields of hippocampal place cells, providing a potential neural substrate for memory problems. Each subfield of the hippocampus carries out unique aspects of spatial memory, yet little is known about how ...
Brittney L. Boublil   +4 more
wiley   +1 more source

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