Results 21 to 30 of about 72,632 (202)

Defects in the medial entorhinal cortex and dentate gyrus in the mouse model of Sanfilippo syndrome type B. [PDF]

open access: yes, 2011
Sanfilippo syndrome type B (MPS IIIB) is characterized by profound mental retardation in childhood, dementia and death in late adolescence; it is caused by deficiency of α-N-acetylglucosaminidase and resulting lysosomal storage of heparan sulfate.
Neufeld, Elizabeth F   +2 more
core   +8 more sources

What Does the Anatomical Organization of the Entorhinal Cortex Tell Us?

open access: yesNeural Plasticity, 2008
The entorhinal cortex is commonly perceived as a major input and output structure of the hippocampal formation, entertaining the role of the nodal point of cortico-hippocampal circuits. Superficial layers receive convergent cortical information, which is
Cathrin B. Canto   +2 more
doaj   +1 more source

An analysis of entorhinal cortex projections to the dentate gyrus, hippocampus, and subiculum of the neonatal macaque monkey. [PDF]

open access: yes, 2014
The entorhinal cortex is the primary interface between the hippocampal formation and neocortical sources of sensory information. Although much is known about the cells of origin, termination patterns, and topography of the entorhinal projections to other
Amaral, D.G., Kondo, H., Lavenex, P.
core   +1 more source

Intrinsic Projections of Layer Vb Neurons to Layers Va, III, and II in the Lateral and Medial Entorhinal Cortex of the Rat

open access: yesCell Reports, 2018
Summary: Layer V of the entorhinal cortex (EC) receives input from the hippocampus and originates main entorhinal outputs. The deep-sublayer Vb, immunopositive for the transcription factor Ctip2, is thought to be the main recipient of hippocampal ...
Shinya Ohara   +7 more
doaj   +1 more source

Entorhinal cortex volume is associated with episodic memory related brain activation in normal aging and amnesic mild cognitive impairment [PDF]

open access: yes, 2011
The present study examined the relationship between entorhinal cortex and hippocampal volume with fMRI activation during episodic memory function in elderly controls with no cognitive impairment and individuals with amnesic mild cognitive impairment ...
deToledo-Morrell, Leyla   +8 more
core   +1 more source

Selective Vulnerability of Neurons in Layer II of the Entorhinal Cortex during Aging and Alzheimer's Disease

open access: yesNeural Plasticity, 2010
All neurons are not created equal. Certain cell populations in specific brain regions are more susceptible to age-related changes that initiate regional and system-level dysfunction.
Alexis M. Stranahan, Mark P. Mattson
doaj   +1 more source

Entorhinal cortex dysfunction in Alzheimer's disease

open access: yesTrends in Neurosciences, 2023
The entorhinal cortex (EC) is the brain region that often exhibits the earliest histological alterations in Alzheimer's disease (AD), including the formation of neurofibrillary tangles and cell death. Recently, brain imaging studies from preclinical AD patients and electrophysiological recordings from AD animal models have shown that impaired neuronal ...
openaire   +4 more sources

Effects of entorhinal cortex lesions on memory in different tasks

open access: yesBrazilian Journal of Medical and Biological Research, 1997
Lesions of the entorhinal cortex produce retrograde memory impairment in both animals and humans. Here we report the effects of bilateral entorhinal cortex lesions caused by the stereotaxic infusion of N-methyl-D-aspartate (NMDA) in rats at two different
G.P. Gutierrez-Figueroa   +2 more
doaj   +1 more source

Rat hippocampal CA1 region represents learning-related action and reward events with shorter latency than the lateral entorhinal cortex

open access: yesCommunications Biology, 2023
The hippocampus and entorhinal cortex are deeply involved in learning and memory. However, little is known how ongoing events are processed in the hippocampal-entorhinal circuit.
Shogo Soma   +8 more
doaj   +1 more source

Structural Analysis of Brain Hub Region Volume and Cortical Thickness in Patients with Mild Cognitive Impairment and Dementia

open access: yesMedicina, 2020
Background and Objectives: A complex network of axonal pathways interlinks the human brain cortex. Brain networks are not distributed evenly, and brain regions making more connections with other parts are defined as brain hubs.
Nauris Zdanovskis   +3 more
doaj   +1 more source

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