Results 71 to 80 of about 1,569,764 (334)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Entropy and Sorting

open access: yesJournal of Computer and System Sciences, 1992
AbstractWe reconsider the old problem of sorting under partial information, and give polynomial time algorithms for the following tasks: (1) Given a partial order P, find (adaptively) a sequence of comparisons (questions of the form, "is x < y?") which sorts ( i.e., finds an unknown linear extension of) P using O(log(e(P))) comparisons in worst case ...
Jeong Han Kim, Jeff Kahn
openaire   +2 more sources

Entropy of Eigenfunctions [PDF]

open access: yes, 2009
We study the high--energy limit for eigenfunctions of the laplacian, on a compact negatively curved manifold. We review the recent result of Anantharaman-Nonnenmacher giving a lower bound on the Kolmogorov-Sinai entropy of semiclassical measures, and improve this lower bound in the case of variable negative curvature.
Anantharaman, Nalini   +2 more
openaire   +4 more sources

The von Neumann entropy asymptotics in multidimensional fermionic systems

open access: yes, 2011
We study the von Neumann entropy asymptotics of pure translation-invariant quasi-free states of d-dimensional fermionic systems. It is shown that the entropic area law is violated by all these states: apart from the trivial cases, the entropy of a cubic ...
Farkas, S., Zimboras, Z.
core   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Smooth Renyi Entropies and the Quantum Information Spectrum

open access: yes, 2008
Many of the traditional results in information theory, such as the channel coding theorem or the source coding theorem, are restricted to scenarios where the underlying resources are independent and identically distributed (i.i.d.) over a large number of
Datta, Nilanjana, Renner, Renato
core   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

On the entropy of LEGO ®

open access: yesJournal of Applied Mathematics and Computing, 2013
13 pages, 7 figures.
Durhuus, Bergfinnur, Eilers, Søren
openaire   +5 more sources

Fluctuation Theorems of Brownian Particles Controlled by a Maxwell's Demon

open access: yes, 2006
We study the stochastic dynamics of Brownian particles in a heat bath and subject to an active feedback control by an external, Maxwell's demon-like agent.
E. Schrödinger   +3 more
core   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

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