Results 161 to 170 of about 341,588 (339)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Paths and stochastic order in open systems

open access: yes, 2011
The principle of maximum irreversible is proved to be a consequence of a stochastic order of the paths inside the phase space; indeed, the system evolves on the greatest path in the stochastic order.
Lucia, Umberto
core  

Generalized black hole entropy is von Neumann entropy

open access: yesPhysical Review D
It has been argued that, while the individual terms in the generalized entropy, Sgen=A/4GN+Sext, are ill-defined in the semiclassical limit, their sum is well-defined if one takes into account perturbative quantum gravitational effects. The first term diverges as GN→0, and the second diverges due to the infinite entanglement across the horizon which is
Jonah Kudler-Flam   +2 more
openaire   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Investigation to define the propagation characteristics of a finite amplitude acoustic pressure wave [PDF]

open access: yes
A theoretical analysis of the propagation characteristics of a finite amplitude pressure wave is presented. The analysis attempts to study the contribution of entropy-producing regions to the mechanism of aerodynamic noise generation.
Cottrell, J. W., Peter, A. C.
core   +1 more source

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