Results 61 to 70 of about 54,636 (287)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Exploration of the High Entropy Alloy Space as a Constraint Satisfaction Problem [PDF]

, 2017
High Entropy Alloys (HEAs), Multi-principal Component Alloys (MCA), or Compositionally Complex Alloys (CCAs) are alloys that contain multiple principal alloying elements. While many HEAs have been shown to have unique properties, their discovery has been
Abu-Odeh, Anas, Arroyave, Raymundo, Chen, Qing, Galvan, Edgar, Kirk, Tanner, Malak, Richard, Mao, Huahai, Mason, Paul   +7 more
core   +1 more source

Exergy Analysis of a Domestic Refrigerator

Journal of Engineering, 2018
An energy and exergy thermodynamic analysis using EES program was done for a domestic refrigerator working with R-134a using vapor compression refrigeration cycle. The analysis deals with the system component, i.e.
Loauy Abd Al-Azez Mahdi, Wahid S. Mohammad, Samir Akram Mahmood   +2 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Improved Asymptotic Key Rate of the B92 Protocol

, 2013
We analyze the asymptotic key rate of the single photon B92 protocol by using Renner's security analysis given in 2005. The new analysis shows that the B92 protocol can securely generate key at 6.5% depolarizing rate, while the previous analyses cannot ...
Matsumoto, Ryutaroh
core   +1 more source

Challenges and progress on the modelling of entropy generation in porous media: a review [PDF]

, 2017
Depending upon the ultimate design, the use of porous media in thermal and chemical systems can provide significant operational advantages, including helping to maintain a uniform temperature distribution, increasing the heat transfer rate, controlling ...
Karimi, Nader, Peterson, G.P., Torabi, Mohsen, Yee, Shannon   +3 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Simplest random K-satisfiability problem

, 2000
We study a simple and exactly solvable model for the generation of random satisfiability problems. These consist of $\gamma N$ random boolean constraints which are to be satisfied simultaneously by $N$ logical variables. In statistical-mechanics language,
A. Barrat, A. Goerdt, B. Aspvall, B. Bollobás, D. Gross, E. Gardner, E. Gardner, Federico Ricci-Tersenghi, G. Biroli, M. Davis, M. Mézard, M. Weigt, M.-T. Chao, Martin Weigt, R. Monasson, R. Monasson, R. Monasson, Riccardo Zecchina, S. Kirkpatrick, S.A. Cook, T.R. Kirkpatrick, V. Chvàtal   +21 more
core   +1 more source

Optimization of peripheral finned-tube evaporators using entropy generation minimization

International Journal of Heat and Mass Transfer, 2012
The peripheral finned-tube (PFT) is a new geometry for enhanced air-side heat transfer under moisture condensate blockage (evaporators). It consists of individual hexagonal (peripheral) fin arrangements with radial fins whose bases are attached to the tubes and tips are interconnected with the peripheral fins.
Pussoli, Bruno, Barbosa Jr., Jader, da Silva, Luciana, Kaviany, Massoud   +3 more
openaire   +3 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source