Results 81 to 90 of about 162,974 (325)

Minimization of entropy generation in heat exchangers

, 2014
131
openaire   +3 more sources

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Minimization of entropy generation rate in methanol steam reforming reactor

Case Studies in Thermal Engineering
The methanol steam reforming (MSR) reaction is a prospective method in hydrogen generation because of its operability and high conversion efficiency. Most of the current thermodynamic studies involving MSR use classical thermodynamic methods, while fewer
Rui Kong, Shaojun Xia, Zhihui Xie, Yu Lin   +3 more
doaj   +1 more source

Radiative thermal criticality and entropy generation of hydromagnetic reactive Powell–Eyring fluid in saturated porous media with variable conductivity

Energy Reports, 2019
Theoretical study of inherent irreversibility and thermal runaway of an exothermic reactive Eyring–Powell fluid flow through a saturated porous fixed horizontal channel with thermal radiation and variable electrical conductivity is investigated.
S.O. Salawu, R.A. Kareem, S.A. Shonola
doaj   +1 more source

Thermodynamic Analysis of a High-Temperature Latent Heat Thermal Energy Storage System

Energies, 2020
Thermal energy storage (TES) technologies are becoming vitally important due to intermittency of renewable energy sources in solar applications. Since high energy density is an important parameter in TES systems, latent heat thermal energy storage (LHTES)
David W. MacPhee, Mustafa Erguvan
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Adaptive compressive tomography: a numerical study

, 2019
We perform several numerical studies for our recently published adaptive compressive tomography scheme [D. Ahn et al. Phys. Rev. Lett. 122, 100404 (2019)], which significantly reduces the number of measurement settings to unambiguously reconstruct any ...
Ahn, D., Hradil, Z., Jeong, H., Koutny, D., Leuchs, G., Rehacek, J., Sanchez-Soto, L. L., Teo, Y. S.   +7 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Fixed-matrix regenerators optimization with wire mesh screens using entropy generation minimization method

AIP Advances
The thermodynamic efficiency of a wire mesh fixed matrix regenerative heat exchanger mainly depends on the regenerator’s heating performance and losses.
Mohammad Saraireh
doaj   +1 more source