Results 151 to 160 of about 7,498,456 (339)
rSEM: System-Entropy-Measure-Guided Routing Algorithm for Industrial Wireless Sensor Networks. [PDF]
Xiong X, Dong C, Niu K.
europepmc +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Learning Entropy: Multiscale Measure for Incremental Learning
First, this paper recalls a recently introduced method of adaptive monitoring of dynamical systems and presents the most recent extension with a multiscale-enhanced approach.
Ivo Bukovsky
doaj +1 more source
Identifying host-specific amino acid signatures for influenza A viruses using an adjusted entropy measure. [PDF]
Zhang Y, Eskridge KM, Zhang S, Lu G.
europepmc +1 more source
Holographic Entropy Cone Measures
8 ...
Bao, Ning, Blitz, Samuel, Stoica, Bogdan
openaire +2 more sources
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Assessing the Effects of Alzheimer Disease on EEG Signals Using the Entropy Measure: A Meta-analysis. [PDF]
Ahmadieh H, Ghassemi F.
europepmc +1 more source
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source

