Results 91 to 100 of about 41,707 (290)
Advanced Science, EarlyView.This study reveals that large tumors secrete more chemokine CXCL3, which recruits immunosuppressive neutrophils to the periphery, thereby impairing the activation and memory of systemic tumor‑reactive CD8+ T cells. CXCL3 antagonism restores systemic immune memory and enhances the antitumor efficacy of anti‑PD‑1 therapy, offering a potential strategy to
Ji Wang +15 more
wiley +1 more source
Haematologica, 2010 Background During the final stages of differentiation of mammalian erythroid cells, the chromatin is condensed and enucleated. We previously reported that Rac GTPases and their downstream target, mammalian homolog of Drosophila diaphanous 2 (mDia2), are ...
Peng Ji +4 more
doaj +1 more source
, 2014 Change in MPF activity in oocytes following DEM-assisted enucleation compared with mechanical enucleation.
Jun-Xue Jin (535028) +10 more
core +1 more source
Erythroblast enucleation is a dynein-dependent process [PDF]
, 2016 Mammalian erythroblasts undergo enucleation through a process thought to be similar to cytokinesis. Microtubule-organizing centers (MTOCs) mediate organization of the mitotic spindle apparatus that separates the chromosomes during mitosis and are known ...
Kobayashi, Isuzu +8 more
core +1 more source
Concurrent Germline RB1 & Mosaic TP53 in a Child With Multiple Childhood Cancers
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT We report a patient with a pathogenic germline variant (PGV) in RB1 and somatic mosaicism for a pathogenic TP53 variant who developed three distinct types of childhood cancer: retinoblastoma, osteosarcoma, and myelodysplastic syndrome (MDS) before the age of 6 years.
Ole Haubjerg Nielsen +8 more
wiley +1 more source
Journal of Clinical Oncology, 2019 PURPOSE Treatment abandonment because of enucleation refusal is a limitation of improving outcomes for children with retinoblastoma in countries with limited resources.
S. Luna-Fineman +16 more
semanticscholar +1 more source
Animal Models and Experimental Medicine, EarlyView.We investigated the therapeutic potential and mechanism of chrysin in experimental diabetic retinal disease. Using a streptozotocin (STZ)‐induced diabetic mouse model and high‐glucose‐stimulated BV2 microglia, we revealed chrysin‐responsive pyroptosis‐associated signatures and identified GBP3 as a regulated node.
Qun Liu +9 more
wiley +1 more source
Safety and outcomes of salvage HoLEP after TURP: a comparative study
The Canadian Journal of UrologyBackground: Recurrent prostate surgery may pose additional challenges for achieving an efficient and anatomically precise enucleation. This research investigates how prior transurethral resection of prostate (TURP) affects the perioperative course ...
Volkan Sabur, Abdullah Gölbaşı
doaj +1 more source
NeuroImage: Clinical, 2015 Purpose: Retinoblastoma is typically diagnosed before 5 years of age and is often treated by enucleation (surgical removal) of the cancerous eye. Here, we sought to characterize morphological changes of the cortex following long-term survival from early ...
Krista R. Kelly +3 more
doaj +1 more source
The Anatomical Record, EarlyView.Abstract Phylogenetic comparative methods have been used in recent literature to work with laws and test for regularities (evolutionary associations of quantitative features) and evolutionary singularities (features that evolved in a single taxon). We analyzed these uses epistemologically, taking the evolution of red‐blood‐cell mean corpuscular volume (
Jorge Cubo +3 more
wiley +1 more source