Results 71 to 80 of about 41,707 (290)

Holmium Laser Enucleation of the Prostate (HoLEP) in Ambulatory Surger [PDF]

, 2015
The focus of this work is the need to give an update on the holmium laser enucleation of the prostate (HoLEP) technique in ambulatory surgery. Indeed, over the last two decades, there has been a significant change in surgical treatment of benign ...
Marc Fourmarier
core  

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

An Aggregation‐Induced Polymerization Poly(Disulfide)‐Drug Nanoplatform for Autoimmune Uveitis Therapy via Inhibiting the cGAS‐STING Pathway

Advanced Science, EarlyView.
A cationic poly(disulfide)‐drug nanoplatform (LA/DexP) was developed to treat experimental autoimmune uveitis (EAU). With potent blood‐retinal barrier penetrability, LA/DexP releases DSP in response to high ROS and scavenges cfDNA to inhibit the cGAS‐STING signaling pathway.
Yuelan Wu, Wenbo Geng, Qinjin Dai, Wanyun Zhang, Yuxian Lai, Pei Zhang, Chunjiang Zhou, Yinuo Wang, Qingfeng Cao, Xiang Luo, Yujie Lai, Changwei Huang, Peizeng Yang   +12 more
wiley   +1 more source

The impact of previous prostate biopsy on the outcomes of bipolar transurethral enucleation of the prostate: a retrospective cohort study

African Journal of Urology
Background In patients who have undergone previous prostate biopsies, surgeons are worried that enucleation may be challenging due to potential adhesions, hematoma, and fibrosis between adenoma and prostatic capsule.
Hussein Mamdoh, Ayman Mousa, Ahmed Eissa, Khaled Almekaty, Tarek Gameel, Maged Ragab, Mohamed Abo El-enen, Ahmed Zoeir   +7 more
doaj   +1 more source

Minimally Invasive Thulium Laser Enucleation of the Prostate

Journal of Urological Surgery
The goal of Minimal Invasive Laser Enucleation of Prostate (MiLEP) surgery is to reduce complication rates and risk of urethral trauma, while providing similar success rates by using smaller caliber instruments. Enucleation was performed with 22 Ch outer
Ahmet Furkan Özsoy, Mehmet İlker Gökçe   +1 more
doaj   +1 more source

Orbital relapse of retinoblastoma in patients with high-risk histopathology features

Therapeutic Advances in Ophthalmology, 2019
Aim: To describe the clinical picture of orbital relapse of retinoblastoma following uncomplicated enucleation. Methods: Case series of two patients with group E retinoblastoma with high-risk features on histopathology, namely, post-laminar optic nerve ...
Maria Vittoria Cicinelli, Swathi Kaliki
doaj   +1 more source

A Rare De Novo Missense Mutation in IFT122 Confers a Genetic Susceptibility Factor of Idiopathic Pediatric Uveitis Via Trio‐based Whole‐Exome Sequencing

Advanced Science, EarlyView.
A rare de novo IFT122‐A773E variant is identified in idiopathic pediatric uveitis and shown to exacerbate retinal inflammation and barrier dysfunction. Mechanistically, the variant enhances IFT43 interaction, elevates calcium signaling, and activates the MEK/ERK/FRA1 axis, revealing a previously unrecognized cilia‐associated pathway that may increase ...
Qian Zhou, Jiaxing Huang, Yilin Wang, Xingran Li, Xianyang Liu, Lingyu Dai, Hongshun Li, Qingfeng Wang, Jiangyi Liu, Guannan Su, Wanyun Zhang, Yang Deng, Qingfeng Cao, Yujie Lai, Xiang Luo, Changwei Huang, Ling Chen, Shengping Hou, Peizeng Yang   +18 more
wiley   +1 more source

New insights into the mechanisms of red blood cell enucleation: From basics to clinical applications

eJHaem
Background Red blood cell (RBC) enucleation is a crucial step in the process of erythropoiesis. By removing the nucleus, RBCs gain greater flexibility, enabling them to traverse narrow capillaries with ease, thereby enhancing the efficiency of oxygen and
Qianli Zhuo, Zhaojun Zhang, Xiangdong Fang   +2 more
doaj   +1 more source

Recurrent giant intrahepatic biliary cystadenoma: Case report and review of Literature

Indian Journal of Medical and Paediatric Oncology, 2020
Biliary cystadenoma is a very rare cystic neoplasm of the liver that usually occurs almost exclusively in middle-aged women. These are slowly progressive tumours and cannot be safely differentiated from cystadenocarcinomas on preoperative imaging and ...
Digvijoy Sharma, Gangadhar Rao Gondu, Venu Madhav Thamma, Surya Ramachandra Varma Gunturi, Kunduru Nava Kishore, Jagan Mohan Reddy, Nagari Bheerappa   +6 more
doaj   +1 more source

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

Advanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert, Christophe Nguyen, Sean Edward Dunn, Magali Gary‐Bobo, Jérôme Lacombe, Justin Moser, Frédéric Zenhausern, Jean‐Olivier Durand, Frédérique Cunin   +8 more
wiley   +1 more source