Results 121 to 130 of about 34,245 (195)

Generation of a Novel Col8a2P2A‐CreERT2 Mouse Line Enables Targeted Genetic Manipulation of Corneal Endothelial Cells and Modeling of Endothelial Decompensation

open access: yesgenesis, Volume 64, Issue 2, April 2026.
ABSTRACT The corneal endothelium is a monolayer of specialized cells that maintains stromal deturgescence and transparency, functions essential for vision. Despite its clinical importance, the developmental origins and homeostatic programs of the endothelium remain poorly understood, in part due to the lack of a lineage‐specific genetic driver.
Yong Yuan   +9 more
wiley   +1 more source

Epidemiology and Clinicopathologic Features with Prognostic Implications of Conventional Ameloblastoma: A 22-Year Retrospective Study. [PDF]

open access: yesHead Neck Pathol
Tikkhanarak K   +8 more
europepmc   +1 more source

Bacillus cereus Induces Necroptosis in Microglia via the RIPK1/3‐MLKL Pathway

open access: yesMicrobiologyOpen, Volume 15, Issue 2, April 2026.
Bacillus cereus induces necroptosis in murine/human microglia via the RIPK1/3‐MLKL pathway, triggering inflammatory cytokine release—uncovering a new pathogenic mechanism for its severe ocular infection. ABSTRACT Bacillus cereus endophthalmitis is a rapidly progressing intraocular infection that often results in poor visual outcomes due to extensive ...
Jing Yang   +7 more
wiley   +1 more source

High‐Purity Functional Corneal Endothelial Cells From Human Induced Pluripotent Stem Cells via a Novel Wash‐Out Method

open access: yesMedComm, Volume 7, Issue 4, April 2026.
iPSC‐derived corneal endothelial cells purified via a novel wash‐out method show high functional fidelity, resemble primary CECs, and restore corneal clarity in vivo, offering a scalable alternative to donor transplantation. ABSTRACT Corneal endothelial failure can cause blindness, with transplantation as the only treatment.
Eun‐Ah Ye   +10 more
wiley   +1 more source

Unraveling the Genetic Mysteries of Müllerian Anomalies: Research Approaches and Clinical Significance

open access: yesClinical Genetics, Volume 109, Issue 4, Page 615-629, April 2026.
This review primarily summarizes the genetic defects in Müllerian anomalies, the tools used to validate these genetic defects, and the future clinical significance of identifying the precise genetic etiology of Müllerian anomalies. ABSTRACT Müllerian anomalies are a collection of heterogeneous anatomical disorders of the female genital tract that ...
Jingfang Li   +5 more
wiley   +1 more source

Histopathology, Diagnosis, Management and Treatment Outcomes of Cemental Tears: A Retrospective Observational Cohort Study

open access: yesInternational Endodontic Journal, Volume 59, Issue 4, Page 614-631, April 2026.
ABSTRACT Introduction Diagnosing cemental tears remains challenging, and treatment outcomes can be unpredictable; recommendations for their diagnosis and management are primarily based on case reports and anecdotal experience. Although a classification has been developed for cemental tears, its clinical applicability and importance have yet to be ...
Angeline Hui Cheng Lee   +3 more
wiley   +1 more source

Soluble Epoxide Hydrolase Inhibitors Improve Cornea Alkali Wound Healing

open access: yesThe FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Soluble epoxide hydrolase (sEH) inhibition enhances corneal wound healing following alkali injury. (A) Schematic representation of corneal injury induced by NaOH or ammonia showing elevated sEH expression in corneal keratocytes. This leads to rapid hydrolysis of epoxy fatty acids (EpFAs), reducing their bioavailability and contributing to enhanced ...
Xiaowen Lu   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy