Results 141 to 150 of about 42,907 (300)

Chemical screen targeting erythroid enucleation.

, 2015
(A) List of molecules targeted in the chemical screen. (B) For the compound screen orthochromatic erythroblasts were isolated by FACS and subsequently incubated in 96-well plates in the presence of the compounds for 5h.
Christina B. Wölwer (827149), Helen B. Pearson (267614), Nathan J. Godde (567811), Sarah M. Russell (136879), Patrick O. Humbert (136871), Kurt Lackovic (794766), Luke B. Pase (827150), David C. S. Huang (104376)   +7 more
core   +1 more source

Five Advances in Benign Pancreatic Surgery in the Last 50 Years

World Journal of Surgery, EarlyView.
Stephan B. Dreyer, Rowan W. Parks
wiley   +1 more source

Stage‐Associated Microglial Subpopulations and Dynamics in Vascular Pathogenesis of Oxygen‐Induced Retinopathy

Cell Proliferation, EarlyView.
In the oxygen‐induced retinopathy (OIR) mouse model, two distinct microglial subpopulations play opposing roles: highly glycolytic microglia (HGM) promote neovascular formation via Pkm2, while Mrc1/CD206‐positive phagocytosis‐associated microglia (PAM) facilitate its regression.
Yuan Ma, Ziye Chen, Baoyi Liu, Wen Ding, Runping Duan, Kangjie Kong, Zhuojun Xu, Jizhu Li, Jiali Ru, Dianlei Guo, Xiaoyue Wei, Yaping Liu, Zhuangling Lin, Yang Meng, Yuan Liu, Lan Jiang, Zitong Chen, Rebiya Tuxun, Chinling Tsai, Chunqiao Liu, Tao Li   +20 more
wiley   +1 more source

Vesicle trafficking plays a novel role in erythroblast enucleation

, 2010
Enucleation of mammalian erythroblasts is a process whose mechanism is largely undefined. The prevailing model suggests that nuclear extrusion occurs via asymmetric cytokinesis. To test this hypothesis, we treated primary erythroblasts with inhibitors of
Ganesan Keerthivasan, John D. Crispino, Amittha Wickrema, Sara Small, Hui Liu   +4 more
core   +1 more source

Delving Into Retinoblastoma Genetics: Discovery of Novel Mutations and Their Clinical Impact: Retrospective Cohort Study

Cancer Medicine
Background Retinoblastoma (Rb) is a rare intraocular malignancy that originates in the retina of children under 5 years of age. Approximately one‐third of children diagnosed with retinoblastoma are associated with germline mutations in one of the RB1 ...
Mohammad Faranoush, Masood Naseripour, Pooya Faranoush, Zeinab Davoodi‐Moghaddam, Alireza Jahandideh, Negin Sadighnia, Delbar Daneshjou, Parisa Shams, Ahad Sedaghat, Reza Mirshahi, Shirin Ravanbod, Farzaneh Nasirnejad, Ali Elahinia, Davood Bashash   +13 more
doaj   +1 more source

Suppression of Retinal Neovascularisation by Tetrahedral Framework Nucleic Acids‐Resveratrol Via Dual Anti‐Angiogenesis and Anti‐Inflammation

Cell Proliferation, EarlyView.
Resveratrol‐loaded tetrahedral framework nucleic acids (tFNAs‐RSV) enable concurrent anti‐angiogenic and anti‐inflammatory therapy, enhancing ocular delivery and bioactivity. In hypoxia‐induced retinal neovascularisation, tFNAs‐RSV reduce neovascular lesions, vascular leakage and inflammatory infiltration by suppressing HIF‐1, p38 MAPK and NF‐κB p65 ...
Yili Jin, Tao Cai, Junyang Huang, Li Chen, Yi Lin, Jingying Liu, You Wang, Xiaoyan Ding   +7 more
wiley   +1 more source

Enucleation and Techniques of Orbital Implant Placement

, 2019
Enucleation is a surgical procedure that involves removal of the eye and anterior optic nerve, most commonly with retention of the extraocular muscles which are then sewn to the implant.
Sara Tullis Wester, Wester, Sara Tullis
core   +1 more source

Equine eyelid reconstruction by semi‐circular skin flap blepharoplasty

Equine Veterinary Education, EarlyView.
Summary Reconstructive surgeries of the equine eyelid carry significant challenges for the equine surgeon, due to the poorly mobile and tightly adhered facial skin in this species. Preservation of lid function is an essential surgical consideration in order to maintain protection of the globe and cornea and to provide ocular comfort to the case ...
V. J. Jordan, D. Leong, C. Hartley
wiley   +1 more source

ALOX15 mediates thrombin‐induced myristoylation, trafficking, and interaction of protease‐activated receptors, leading to platelet activation and hemostasis

The FEBS Journal, EarlyView.
The role of PARs in platelet function is fairly known; however, the underlying mechanisms are not fully understood. We report that thrombin myristoylates PAR4 in mouse platelets and PAR1 and PAR4 in human platelets, facilitating their membrane transport and interaction, leading to PAR3/4 heterodimers in mice and PAR1/4 heterodimers in humans.
Suresh Govatati, Chandra Sekhar Yadavalli, Md Monirul Hoque, Swapna Thota, Gadiparthi N. Rao   +4 more
wiley   +1 more source

Enucleation of Buffalo Oocytes: A Comparison of Methods

, 2013
A comparative study of three enucleation methods; enucleation by pushing out small amount of cytoplasm beneath the first polar body, enucleation by bisectioning of oocytes, and enucleation by aspiration were carried out using the oocytes of Indian ...
Singla, Suresh K., Sahoo, Lakshman
core