Results 61 to 70 of about 65,509 (291)

5‐Hydroxymethylcytosine Dynamics Reveals Coordinated Reprogramming of Parental Genomes and X Chromosome Dosage Balance in Mouse SCNT Embryos

Advanced Science, EarlyView.
Genome‐wide, high‐resolution profiling of hydroxymethylation in mouse SCNT embryos reveals a transient, allele‐symmetric 5hmC reprogramming pattern distinct from natural embryos, with X‐chromosomes and imprinting control regions resistant to proper remodeling.
Zeming Xiang, Rui Yan, Jing Guo, Mengyao Wang, Xin Cheng, Fan Zhang, Tianzi Guo, Xin Long, Fan Guo, Dan Liang   +9 more
wiley   +1 more source

New insights into the mechanisms of red blood cell enucleation: From basics to clinical applications

eJHaem
Background Red blood cell (RBC) enucleation is a crucial step in the process of erythropoiesis. By removing the nucleus, RBCs gain greater flexibility, enabling them to traverse narrow capillaries with ease, thereby enhancing the efficiency of oxygen and
Qianli Zhuo, Zhaojun Zhang, Xiangdong Fang   +2 more
doaj   +1 more source

Clinical presentation, management and follow-up of 83 patients with Leydig cell tumors of the testis: a prospective case-cohort study [PDF]

, 2019
LCTs are more frequent than generally believed, are associated with male infertility, cryptorchidism and gynecomastia, and should be treated conservatively (in compliant patients) with active surveillance, which appears to be a safe alternative to ...
Cantisani, Vito, Fattorini, Giorgio, Franco, Giorgio, Gianfrilli, Daniele, Isidori, Andrea M, Lenzi, Andrea, Leonardo, Costantino, Pofi, Riccardo, Pozza, Carlotta, Sbardella, Emilia, Tarsitano, Maria Grazia, Tenuta, Marta, Testis, Unit   +12 more
core   +1 more source

Development of Teleoperated Robotic System for Remote Intraocular Microsurgery

Advanced Science, EarlyView.
A teleoperated robotic system, characterized by micrometer‐scale precision and a remote center of motion design, is developed and validated to ensure the safety and flexibility of remote intraocular surgery. This system exhibits superior performance in experimental evaluations and holds significant potential for advancing remote microsurgery ...
Andi Xu, Zhangkai Lian, Wenben Chen, Yanlin Li, Jiali Liu, Hongli Liang, Rihui Song, Zikai Lin, Mingyuan Li, Yining Huang, Ling Jin, Zheming Zhang, Xiaoyue Wei, Bingqian Liu, Wei Ma, Tao Li, Hang Shao, Wei Liu, Kun Gao, Xin Zhang, Pisong Yan, Ruiyang Li, Ruixin Wang, Xiaohang Wu, Duoru Lin, Xiang Chen, Jinghui Wang, Xingwu Zhong, Mohammad Ali Nasseri, Kai Huang, Haotian Lin   +30 more
wiley   +1 more source

Importance of Different Modalities of Treatment For the Management of Keratocystic Odontogenic Tumour with Five year follow-up [PDF]

Journal of Clinical and Diagnostic Research, 2014
Background: The keratocystic odontogenic tumors is a benign but one of most aggressive developmental cyst with many distinguishing clinical and histologic features and high recurrence rate. In the given study, authors have studied and presented their
Vijay Ebenezer, Balakrishnan Ramalingam
doaj   +1 more source

Transplantable melanomas in hamsters and gerbils as models for human melanoma : sensitization in melanoma radiotherapy : from animal models to clinical trials [PDF]

, 2018
The focus of the present review is to investigate the role of melanin in the radioprotection of melanoma and attempts to sensitize tumors to radiation by inhibiting melanogenesis. Early studies showed radical scavenging, oxygen consumption and adsorption
Andrzej Słominski, Anna Brożyna, Anna Markiewicz, Bożena Romanowska-Dixon, Ewa Podgórska, Krystyna Urbańska, Martyna Elas, Martyna Śniegocka, Małgorzata Szczygieł, Michał Żmijewski, Mirosława Cichorek, Przemysław Płonka   +11 more
core   +1 more source

Human myiasis in Ecuador. [PDF]

, 2020
We review epidemiological and clinical data on human myiasis from Ecuador, based on data from the Ministry of Public Health (MPH) and a review of the available literature for clinical cases.
Calvopina, M, Castañeda, B, Cooper, PJ, Cueva, I, Ortiz-Prado, E, Rodriguez-Hidalgo, R   +5 more
core   +1 more source

Microenvironment Self‐Adaptive Nanoarmor to Address Adhesion‐ and Colonization‐Related Obstacles in Impaired Intestine Promote Bacteriotherapy Against Parkinson's Disease

Advanced Science, EarlyView.
A microenvironment self‐adaptive nanoarmor is developed to effectively address the adhesion‐ and colonization‐related challenges posed by multiple physiological and pathological characteristics in the intestine. L. plantarum@MPN@CS showed significant therapeutic potential in treating Parkinson's disease (PD), a model for extraintestinal disorders, as ...
Limeng Zhu, Yuyu Wu, Yingjie Chen, Xiyi Chen, Xingjie Zan, Yanlong Liu, Wujun Geng   +6 more
wiley   +1 more source

Innovative endoscopic enucleations of the prostate – Xie's Prostate Enucleations

Asian Journal of Urology, 2018
In the past 2 decades, endoscopic enucleation of the prostate has become a safe and effective surgical treatment for benign prostatic hyperplasia (BPH), with comparable outcomes to traditional surgeries.
Liping Xie, Xiao Wang, Hong Chen, Xiangyi Zheng, Ben Liu, Shiqi Li, Yeqing Mao, Qiqi Mao, Song Wang, Jiangfeng Li, Tillmann Loch   +10 more
doaj   +1 more source

Syntaxin 3B Mediates Light‐Dependent Interactions with STXBP1 and Arrestin 4: Distinct Roles in Rods and Cones

Advanced Science, EarlyView.
The present study investigates a cone‐specific STX3 knockout model, displaying a complete loss of cone function, a later onset reduction in rod function, and photoreceptor cell death. A cone‐specific depletion of STXBP1 and ARR4 could be observed in this model.
Lars Tebbe, Larissa Ikelle, Mustafa S. Makia, Mashal Kakakhel, Muayyad R. Al‐Ubaidi, Muna I. Naash   +5 more
wiley   +1 more source