Results 61 to 70 of about 89,016 (337)

Risk Factors for Enucleation Following Open Globe Injury: A 17-Year Experience

Clinical Ophthalmology, 2022
Avi Toiv, Asad F Durrani, Yunshu Zhou, Peter Y Zhao, David C Musch, Michael J Huvard, David N Zacks Department of Ophthalmology and Visual Sciences, W K Kellogg Eye Center, University of Michigan Medical School, Ann Arbor, MI, USACorrespondence: David N ...
Toiv A, Durrani AF, Zhou Y, Zhao PY, Musch DC, Huvard MJ, Zacks DN   +6 more
doaj  

Single‐Cell Transcriptome Analysis Reveals That Hmga2 Regulates Neuroinflammation and Retinal Function by Modulating Müller Cell Autophagy Through PI3K/AKT Signaling Following MCAO‐Induced Retinal Ischemia

Advanced Science, EarlyView.
Employing snRNA‐seq post‐MCAO‐induced retinal ischemia (RI), this study revealed a novel Hmga2‐high Müller cell subpopulation. Hmga2 knockout alleviated neuroinflammation and RI symptoms, potentially by binding PI3K and regulating Müller cell autophagy.
Weihao Lv, Juzheng Yuan, Zhe Ruan, Ya‐nan Dou, Hongchen Zhang, Xiaowei Fei, Leiying Chen, Zehan Zhang, Kai Yang, Xiuquan Wu, Zhou Fei, Fei Fei   +11 more
wiley   +1 more source

Formation of mammalian erythrocytes: chromatin condensation and enucleation [PDF]

, 2011
In all vertebrates, the cell nucleus becomes highly condensed and transcriptionally inactive during the final stages of red cell biogenesis. Enucleation, the process by which the nucleus is extruded by budding off from the erythroblast, is unique to ...
Ji, Peng, Lodish, Harvey F., Murata-Hori, Maki   +2 more
core   +1 more source

Continuous Suppression of Pathological Retinal and Choroidal Neovascularization in Cynomolgus Monkeys via Noninvasive Ophthalmic Delivery of a Novel Anti‐VEGFA Nanobody and Proprietary Penetratin Analog Formulation

Advanced Science, EarlyView.
Pathological retinal/choroidal neovascularization drives vision loss in DR and AMD. Current anti‐VEGF injections, while effective, require invasive, frequent administration. Pene/LQ015, is developed a novel topical anti‐VEGFA nanobody formulation achieving therapeutic intraocular levels through penetratin analog‐enhanced delivery.
Chong Chen, Min Zhu, Xingyan Fan, Kangjia Lv, Kuan Jiang, Yuchen Zhang, Haoliang Zhang, Xinming Qi, Benjamin TK Lee, Yakun Wan, Gang Wei, Kun Liu, Xun Xu   +12 more
wiley   +1 more source

The impact of previous prostate biopsy on the outcomes of bipolar transurethral enucleation of the prostate: a retrospective cohort study

African Journal of Urology
Background In patients who have undergone previous prostate biopsies, surgeons are worried that enucleation may be challenging due to potential adhesions, hematoma, and fibrosis between adenoma and prostatic capsule.
Hussein Mamdoh, Ayman Mousa, Ahmed Eissa, Khaled Almekaty, Tarek Gameel, Maged Ragab, Mohamed Abo El-enen, Ahmed Zoeir   +7 more
doaj   +1 more source

Ejaculation-sparing enucleation of benign prostate hyperplasia: is it almost feasible?

Вестник урологии, 2023
Introduction. Patients often request maintenance of antegrade ejaculation, and try to find the clinic, surgeon, and treatment to store it. Despite an established technique, the long-term results of ejaculation-sparing operations at a large prostate ...
A. G. Martov, D. V. Ergakov, K. A. Asliev, N. A. Baykov   +3 more
doaj   +1 more source

Variations in Innate Immune Cell Subtypes Correlate with Epigenetic Clocks, Inflammaging and Health Outcomes

Advanced Science, EarlyView.
This study uses a high‐resolution DNA methylation reference panel for 19 immune cell‐types, as well as transcriptomic, metabolomic, and large population cohort data to show that age‐related epigenetic heterogeneity within monocytes correlates with inflammaging, biological age, and all‐causemortality, and does so more strongly than existing monocyte ...
Xiaolong Guo, Josephine A. Robertson, Andrea Aparicio, Kirsten Seale, Qingwen Chen, Anne Richmond, Zhaozhen Du, Mahnoor Sulaiman, Shijie C Zheng, Esteban Ballestar, Charlotte AM Cecil, Bastiaan T Heijmans, Steve Horvath, Varun B. Dwaraka, Jessica Lasky‐Su, Ryan Smith, Riccardo E. Marioni, Andrew E Teschendorff   +17 more
wiley   +1 more source

Minimally Invasive Thulium Laser Enucleation of the Prostate

Journal of Urological Surgery
The goal of Minimal Invasive Laser Enucleation of Prostate (MiLEP) surgery is to reduce complication rates and risk of urethral trauma, while providing similar success rates by using smaller caliber instruments. Enucleation was performed with 22 Ch outer
Ahmet Furkan Özsoy, Mehmet İlker Gökçe   +1 more
doaj   +1 more source

Orbital relapse of retinoblastoma in patients with high-risk histopathology features

Therapeutic Advances in Ophthalmology, 2019
Aim: To describe the clinical picture of orbital relapse of retinoblastoma following uncomplicated enucleation. Methods: Case series of two patients with group E retinoblastoma with high-risk features on histopathology, namely, post-laminar optic nerve ...
Maria Vittoria Cicinelli, Swathi Kaliki
doaj   +1 more source

Innovative endoscopic enucleations of the prostate – Xie's Prostate Enucleations

Asian Journal of Urology, 2018
In the past 2 decades, endoscopic enucleation of the prostate has become a safe and effective surgical treatment for benign prostatic hyperplasia (BPH), with comparable outcomes to traditional surgeries.
Liping Xie, Xiao Wang, Hong Chen, Xiangyi Zheng, Ben Liu, Shiqi Li, Yeqing Mao, Qiqi Mao, Song Wang, Jiangfeng Li, Tillmann Loch   +10 more
doaj   +1 more source