Results 81 to 90 of about 89,016 (337)

A Dynamic DNA Nano‐Antioxidant Targeting Galectin‐3 Attenuates Liver Fibrosis via Reducing Macrophage Oxidative Stress

open access: yesAdvanced Science, EarlyView.
This study developed a dynamic DNA nano‐antioxidant (DDN) for Galectin‐3 siRNA delivery, specifically targeting hepatic macrophages to suppress ROS‐driven fibrosis. DDN enhanced hepatic accumulation, restored NRF2 signaling, and attenuated oxidative stress, collagen deposition, and fibrotic progression in a CCl4‐induced cirrhosis model, demonstrating ...
Mengjia Peng   +6 more
wiley   +1 more source

Robotic enucleation of a biliary adenofibroma [PDF]

open access: bronze, 2021
Elizabeth Blears   +2 more
openalex   +1 more source

Standardized Reporting of Microscopic Renal Tumor Margins: Introduction of the Renal Tumor Capsule Invasion Scoring System [PDF]

open access: yes, 2017
Purpose Renal tumor enucleation allows for maximal parenchymal preservation. Identifying pseudocapsule integrity is critically important in nephron sparing surgery by enucleation.
Boris, Ronald S.   +10 more
core   +1 more source

Assessing full thickness oral mucosal grafting: complications and postoperative outcomes in a broad collective of patients [PDF]

open access: yes, 2020
Background: Conjunctival defects can be repaired with several mucosal tissues. The simplicity of harvesting oral mucosa and its wide availability makes it the preferred graft tissue for all indications requiring mucosal grafting. Through analysing the
Bertelmann, Eckart   +2 more
core   +1 more source

PDZK1 Protects Against RPE Senescence by Targeting the 14‐3‐3ε‐mTOR Axis to Attenuate Early Diabetic Retinopathy

open access: yesAdvanced Science, EarlyView.
PDZK1 down‐regulation couples high‐glucose stress to RPE senescence via a PDZK1–14‐3‐3ε–mTOR axis. Restoring PDZK1 or clearing senescent cells rescues retinal homeostasis and mitigates early diabetic retinopathy (DR). This study provides direct evidence linking RPE cell senescence to DR pathogenesis and reveals a promising therapeutic strategy for DR ...
Jian Zhao   +6 more
wiley   +1 more source

Keratocystic Odontogenic Tumour with Extraosseal Spread: Evaluation of the Effect Carnoy’s Solution

open access: yesPrague Medical Report, 2015
Keratocystic odontogenic tumour is relatively rare benign tumour. It is characterized by its fast aggressive growth and high risk of recurrence. Treatment is always surgical: conservative (enucleation, marsupialization) or aggressive (enucleation ...
Jitka Levorová   +4 more
doaj   +1 more source

Management of inflammatory dentigerous cysts in children : report of two cases [PDF]

open access: yes, 2010
Inflammatory dentigerous cysts are usually associated with a carious or non-vital primary tooth. Consequently they are found in children with a mixed dentition.
Azzopardi, Alexander, Scerri, Erica
core  

Robotic Partial Nephrectomy for a Peripheral Renal Tumor [PDF]

open access: yes, 2018
Partial nephrectomy (PN) is the preferred surgical treatment for T1 renal tumors whenever technically feasible. When properly performed, it allows preservation of nephron mass without compromising oncologic outcomes.
Cooper, Caleb A.   +2 more
core   +1 more source

Red Blood Cell‐Derived Exosomal miR‐93‐5p Promotes Lung Cancer Progression through PTEN Suppression

open access: yesAdvanced Science, EarlyView.
Red blood cell (RBC)‐derived exosomal miR‐93‐5p is elevated in lung cancer patients and correlates with poor outcomes. Exosomal miR‐93‐5p suppresses PTEN in cancer cells, enhancing proliferation, migration, and invasion. In mouse models, therapeutic inhibition with ASO‐miR‐93 5p reduces tumor growth, highlighting a bidirectional tumor‐RBC‐tumor axis ...
Ning Li   +4 more
wiley   +1 more source

Penetrating eye injuries at the workplace : case reports and discussion [PDF]

open access: yes, 2010
We describe two recent cases of penetrating eye injury seen at Mater Dei Hospital, both resulting in a poor final outcome and illustrating the importance of wearing appropriate eye protection at the workplace. In case 1, injury was caused by a metal chip
Agius, Maria, Vella Briffa, Benedict
core  

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