Results 11 to 20 of about 39,778 (196)

Detecting early memory changes in preclinical Alzheimer's disease using TabCAT Favorites Test: data from the European Prevention of Alzheimer's Dementia cohort [PDF]

open access: yesAlzheimers Dement
Abstract Background Sensitive memory paradigms are needed to detect subtle memory changes associated with early Alzheimer's disease (AD) pathology in individuals without established clinical symptomatology. We explored cross‐sectional associations between performance on a brief computerized episodic memory test with AD cerebrospinal fluid (CSF ...
Brugulat‐Serrat A   +8 more
europepmc   +2 more sources

Efficacy of a Multicomponent Intervention for Frailty or Physical Function in Prefrail or Frail Older Adults: FRAILMERIT Multicenter Clinical Trial. [PDF]

open access: yesJ Am Geriatr Soc
Clinical management of the older adult. ABSTRACT Objectives Frailty is a common condition in community‐dwelling older adults with high health and socioeconomic implications. However, primary care‐led randomized trials have been scarcely tested. Design Multicenter cluster randomized clinical trial.
Abizanda Saro A   +23 more
europepmc   +2 more sources

Estrategia y plan de acción mundiales sobre el envejecimiento y la salud, 2016-2020 [PDF]

open access: yes, 2016
La 69ª Asamblea Mundial de la Salud, convocada por la OMS aprobó la “Estrategia y plan de acción mundiales sobre el envejecimiento y la salud 2016-2020”, cuyos objetivos estratégicos son:Compromiso para adoptar medidas sobre el envejecimiento saludable ...
Abellán García, Antonio   +1 more
core   +1 more source

Late motherhood linked to accelerated memory decline in amyloid‐positive cognitively unimpaired women [PDF]

open access: yesAlzheimers Dement
Abstract Background Both nulliparity and multiparity have been linked to an increased risk of dementia. However, evidence is inconclusive and requires further study. To further investigate the link between pregnancy history and cognition, we explored the link between age at first childbirth and cognitive change in cognitively unimpaired (CU) women and ...
Brugulat‐Serrat A   +10 more
europepmc   +2 more sources

Detecting Amyloid–β Pathology in Subjective Cognitive Decline using novel CSF and plasma biomarkers [PDF]

open access: yesAlzheimers Dement
Abstract Background Cerebrospinal fluid (CSF) and blood‐based biomarkers are essential tools for detecting individuals with cognitive complaints and at‐risk of Alzheimer's disease (AD). However, their utility in detecting underlying AD pathology in subjective cognitive decline (SCD) remains to be fully established, and direct comparisons between ...
Contador J   +24 more
europepmc   +2 more sources

Association of graph network properties with Alzheimer's pathological hallmarks early in the disease continuum [PDF]

open access: yesAlzheimers Dement
Abstract Background Altered resting‐state functional connectivity (RSFC) has been reported in early Alzheimer's disease (AD). Graph metrics derived from RSFC networks provide valuable insights into brain organization. However, their potential in characterizing early network dysfunction and their relationship with AD biomarkers and cognitive performance
Lizarraga A   +14 more
europepmc   +2 more sources

Factores de riesgo de fractura incidente en pacientes con cáncer de mama tratadas con inhibidores de la aromatasa: cohorte B-ABLE

open access: yesRevista de Osteoporosis y Metabolismo Mineral, 2020
Objetivo: Los inhibidores de la aromatasa (IA) se han asociado con una pérdida de masa ósea acelerada y un mayor riesgo de fracturas osteoporóticas.
García-Giralt N   +7 more
doaj   +1 more source

Recent Approaches to Determine Static and Dynamic Redox State-Related Parameters

open access: yesAntioxidants, 2022
Oxidative stress refers to an imbalance between oxidant and antioxidant molecules, which is usually associated with oxidative damage to biomolecules and mitochondrial malfunction. Redox state-related parameters include (1) the direct measurement of ROS, (
Cristina Mas-Bargues   +2 more
doaj   +1 more source

Hacia el envejecimiento activo y saludable: una experiencia de cine-debate en jubilados

open access: yesNova Scientia, 2021
Introducción: Ante el potencial del cine para formar hacia el envejecimiento activo y saludable, sumado a las amplias recomendaciones fílmicas existentes donde los protagonistas son precisamente adultos mayores en proceso de jubilación y vejez, se ...
María de los Ángeles Aguilera-Velasco   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy