Results 41 to 50 of about 101,226 (206)

The mediating role of neuroimaging-derived biological brain age in the association between risk factors for dementia and cognitive decline in middle-aged and older individuals without cognitive impairment: a cohort study

The Lancet. Healthy Longevity
Summary: Background: Neuroimaging-based brain-age delta has been shown to be a mediator linking cardiovascular risk factors to cognitive function.
Irene Cumplido-Mayoral, MSc, Anna Brugulat-Serrat, PhD, Gonzalo Sánchez-Benavides, PhD, Armand González-Escalante, MSc, Federica Anastasi, PhD, Marta Milà-Alomà, PhD, David López-Martos, MSc, Muge Akinci, MSc, Carles Falcón, PhD, Mahnaz Shekari, MSc, Raffaele Cacciaglia, PhD, Eider M Arenaza-Urquijo, PhD, Carolina Minguillón, PhD, Karine Fauria, PhD, José Luis Molinuevo, MD PhD, Marc Suárez-Calvet, MD PhD, Oriol Grau-Rivera, MD PhD, Verónica Vilaplana, PhD, Juan Domingo Gispert, PhD, R AQUITE AGUILAR, A BETETA GORRITI, A BRUGULAT SERRAT, R E CACCIAGLIA, L CANALS GISPERT, A CAÑAS MARTINEZ, M DEL CAMPO MILAN, C DEULOFEU GOMEZ, R DOMINGUEZ IGLESIAS, M EMILIO, K M E FAURIA, A FERNANDEZ, S D FUENTES JULIAN, P GENIUS SERRA, J D GISPERT LOPEZ, A GONZALEZ ESCALANTE, O GRAU RIVERA, L HERNANDEZ PENAS, G HUESA RODRÍGUEZ, J HUGUET NINOU, L IGLESIAS GAMEZ, I KNEZEVIC, P MARNE ALVAREZ, T MENCHON DIAZ, C MINGUILLON GIL, E PALACIOS, M PASCUAL, W PELKMANS, A POLO BALLESTER, S PRADAS MENDEZ, I A RADOI, B RODRIGUEZ FERNANDEZ, L ROS FREIXEDES, A SALA-VILA, G A SANCHEZ BENAVIDES, M SHEKARI, L SOLSONA HARSTER, A SOTERAS PRAT, L STANKEVICIUTE, M SUAREZ CALVET, M VILANOVA JARAMILLO, N VILOR TEJEDOR   +60 more
doaj   +1 more source

Real‐World Effectiveness and Safety of Finerenone in People With Type 2 Diabetes and Chronic Kidney Disease: A Spanish Multicentre Retrospective Observational Study (MEDFINE‐RWD)

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9461-9472, October 2026.
ABSTRACT Aim Although finerenone has shown efficacy in randomized trials, evidence from routine clinical practice remains limited. We aimed to assess the real‐world effectiveness and safety of finerenone in people with type 2 diabetes (PWT2D) and chronic kidney disease (CKD), with a particular focus on residual cardiorenal risk as reflected by changes ...
Oscar Moreno‐Pérez, Antonio Tejera‐Muñoz, Patricia Tomás‐Gómez, Federico Vázquez‐San Miguel, Virginia Soria‐Utrilla, Ada María Roldán‐Sánchez, Maya Sánchez‐Baya, Jersy Cárdenas‐Salas, Blanca Timón‐Vázquez, Juan J. Gorgojo‐Martínez, Ines Modrego‐Pardo, Irea Fernández‐Xove, Jose Carlos Fernández‐García, Rebeca Reyes‐García   +13 more
wiley   +1 more source

50 preguntas sobre tecnologías para un envejecimiento activo y saludable (Edición española) [PDF]

Este manual sobre tecnologías para un envejecimiento activo y saludable, también conocido como Vida Asistida Activa (Active Assisted Living - AAL en sus siglas en inglés), ha sido creado como parte de la Acción COST GoodBrother, que se ha llevado a cabo ...
Ilgaz, Aysegul, Dogru-Huzmeli, Esra, Dantas, Carina, Jevremovic, Aleksandar, Mujirishvili, Tamara, van Staalduinen, Wilhelmina, Hosseini-Kivanani, Nina, Petrova, Galidiya, Kuźmicz, Maksymilian M., Dahabiyeh, Laila, Jovanovic, Mladjan, Santofimia, Maria Jose, Ekenel, Hazim Kemal, Solanas, Agusti, Coelho, Paulo, Luna, Ferlanda, Ake-Kob, Alin, Machado, Natália, Santofimia Romero, Maria José, Lameski, Petre, Puaschitz, Nathalie G.S., Klimczuk, Andrzej, Staalduinen, Wilhelmina van, Florez-Revuelta, Francisco, Colonna, Liane, Yazici, Ziya Ata, Pajalic, Zada, Climent-Perez, Pau, Ekenel, Hazım Kemal   +28 more
core   +1 more source

Envejecimiento saludable y deterioro cognitivo.

Revista de Neuro-Psiquiatría, 2019
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openaire   +4 more sources

Level of functional independence and personal and social determinants of healthy aging in Peruvian older adults during COVID-19

MedUNAB
Introduction. The population of older adults reached 900 million in 2010 and is projected to double by 2050. For this reason, it is crucial to understand the factors that affect this population’s autonomy. This study sought to identify individual, social,
Enriquez-Canto, Yordanis, Pizarro-Andrade, Rocío de las Nieves   +1 more
doaj   +1 more source

Decoding the Heterogeneity of Diffuse Large B‐Cell Lymphomas: A Comprehensive Genetic, Transcriptomic, and Phenotypic Profiling of B‐Cell Lymphoma Cell Lines

Hematological Oncology, Volume 44, Issue 5, September 2026.
ABSTRACT Diffuse large B‐cell lymphoma (DLBCL) is the most prevalent form of non‐Hodgkin lymphoma, exhibiting significant molecular and clinical heterogeneity. Advances in classification integrating phenotypic, genetic, and transcriptomic features have improved diagnosis and prognosis.
Marina Pérez‐Aguilera, Lucía Pedrosa, Sagrario Gómez, Sara Salazar‐Ortego, Ismael Fernández‐Miranda, Rafael Muñoz‐Viana, Paloma Martín‐Acosta, Beatriz L. Martín‐Lunas, Rebeca Jimeno, Natalia Yanguas‐Casás, Beatriz Horcajo, Giovana Roncador, José A. Martínez‐Climent, Ana Ortega‐Molina, Margarita Sánchez‐Beato   +14 more
wiley   +1 more source

Role of sarcopenia, obesity and sarcopenic obesity in frailty, frailty transitions and death

BMC Geriatrics
Background & aims The role of sarcopenic obesity in the transitions of frailty has been largely neglected. The aim of this study is to assess the role of sarcopenic obesity with prevalent frailty, frailty transitions and mortality.
Alejandro Álvarez-Bustos, Jose A Carnicero, Walter Sepúlveda-Loyola, Francisco J Garcia-Garcia, Leocadio Rodríguez-Mañas   +4 more
doaj   +1 more source

Gender Differences in Circulating TFAM Levels Are Associated with Functional Impairment and Sarcopenia

Biomedicines
Background/Objectives: Mitochondrial dysfunction contributes to age-related muscle decline. Mitochondrial transcription factor A (TFAM), a key regulator of mitochondrial biogenesis, may serve as a marker of chronic inflammation and cellular stress when ...
Olga Laosa, Aitor Carretero, Leocadio Rodríguez-Mañas, Jose Antonio Carnicero, José Viña, Maria Carmen Gómez-Cabrera, Javier Angulo, Francisco José García-García, Mariam El Assar   +8 more
doaj   +1 more source

Impact of Human Melanopsin Gene (OPN4) Polymorphisms (I394T, P10L) on Nocturnal Melatonin and Daily Rhythms in Young Adults

Journal of Pineal Research, Volume 78, Issue 5, September 2026.
ABSTRACT The present study investigates the impact of two missense SNPs in the human melanopsin gene OPN4 ‐I394T (rs1079610) and P10L (rs2675703)‐ on non‐image‐forming (NIF) physiological and behavioural outputs in healthy young adults under real‐world conditions.
Jesús Vicente‐Martínez, María Ángeles Bonmatí‐Carrión, Ana María López‐Parra, Juan Antonio Madrid, Pedro Francisco Almaida‐Pagán, María Angeles Rol   +5 more
wiley   +1 more source

Balneotherapy for the treatment of post-COVID syndrome: a randomized controlled trial

BMC Complementary Medicine and Therapies
Background Post-Acute COVID Syndrome (PACS) is a complex disorder that currently lacks effective evidenced-based therapies to manage it. This randomized controlled trial aims to evaluate the effects of balneotherapy (BT) on PACS symptomatology.
Diana Ovejero, Anna Ribes, Judit Villar-García, Marta Trenchs-Rodriguez, Daniel Lopez, Xavier Nogués, Robert Güerri-Fernandez, Natalia Garcia-Giralt   +7 more
doaj   +1 more source