Results 51 to 60 of about 1,784 (173)

The landscape of dementia research, diagnosis, treatment, and care in Latin America

open access: yesAlzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract Latin America is undergoing rapid population aging alongside a rising burden of dementia. While the region holds substantial potential for dementia risk reduction, challenges remain, such as delayed diagnoses, limited access to specialized care and biomarker testing, persistent stigma, and deep‐rooted structural inequities.
Claudia K. Suemoto   +41 more
wiley   +1 more source

Subjects with Impaired Fasting Glucose: Evolution in a Period of 6 Years

open access: yesJournal of Diabetes Research, 2014
Aim. To study the evolution of impaired fasting glucose (IFG), considering glucose and HbA1c levels and risk factors associated, in a period of 6 years. Methods.
E. Leiva   +9 more
doaj   +1 more source

N‐Acetylglucosamine Selectively Attenuates Neuroinflammation in a Mouse Model of Mitochondrial Dysfunction

open access: yesActa Physiologica, Volume 242, Issue 3, March 2026.
ABSTRACT Aim Mitochondrial dysfunction plays a central role in multiple neurodegenerative diseases, yet the temporal sequence of cellular events underlying neurodegeneration remains poorly defined. This study aimed to characterize the progression of neurodegeneration in a mouse model of fatal mitochondrial encephalopathy and to evaluate the therapeutic
Laura Jiménez‐Sánchez   +12 more
wiley   +1 more source

Efficacy of a Multicomponent Intervention for Frailty or Physical Function in Prefrail or Frail Older Adults: FRAILMERIT Multicenter Clinical Trial

open access: yesJournal of the American Geriatrics Society, Volume 74, Issue 3, Page 658-668, March 2026.
Clinical management of the older adult. ABSTRACT Objectives Frailty is a common condition in community‐dwelling older adults with high health and socioeconomic implications. However, primary care‐led randomized trials have been scarcely tested. Design Multicenter cluster randomized clinical trial.
Adriana Abizanda Saro   +86 more
wiley   +1 more source

Circadian system functional status and sleep in blind subjects with and without conscious light perception

open access: yesFrontiers in Physiology
To understand circadian rhythms and sleep in an understudied population, which is particularly prone to suffer chronodisruption (CD), eighteen blind volunteers of 51.5 ± 3.6 years (Mean ± SEM) and 26 volunteers (51.8 ± 1.2) with no visual impairments ...
David Martínez-Martínez   +13 more
doaj   +1 more source

Differential contribution of T‐type voltage‐gated calcium channels to vascular reactivity in the aorta and renal artery of healthy rabbits

open access: yesExperimental Physiology, Volume 111, Issue 3, Page 1498-1512, 1 March 2026.
Abstract figure T‐type VGCCs contribute to the contraction of the rabbit aorta and modulate both contraction and vasodilation in the rabbit renal artery. α1, alpha 1 adrenergic receptor; ATR, angiotensin II receptor; Ang II, angiotensin II; CaM, calmodulin; Cav3, T‐type voltage‐gated Ca2⁺ channels; cGMP, cyclic guanidine monophosphate; EC, endothelial ...
Andrea Suarez   +6 more
wiley   +1 more source

Detecting early memory changes in preclinical Alzheimer's disease using TabCAT favorites test: Data from the European Prevention of Alzheimer's Disease (EPAD) cohort

open access: yesAlzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Sensitive memory paradigms may allow the detection of subtle memory changes associated with early Alzheimer's pathology in individuals without established clinical symptomatology. METHODS We explored the cross‐sectional association between performance on Tablet‐based Cognitive Assessment Tool (TabCAT) Favorites, a brief ...
Anna Brugulat‐Serrat   +9 more
wiley   +1 more source

El Envejecimiento Activo y Saludable: Una Revisión Sistemática de la Literatura Científica del Ámbito Social

open access: yesResearch on Ageing and Social Policy
El aumento de la esperanza de vida y que la generación Baby Boom se esté aproximando a una edad adulta mayor, precisará de unos cambios en las políticas sociales. En este aspecto, la promoción de un envejecimiento activo y saludable es vital. Para ello,
Stella Iantzi-Vicente
doaj   +1 more source

Relationship between locus coeruleus and slow‐wave sleep in aging and Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Sleep disruption, particularly loss of slow‐wave sleep (SWS), is common in Alzheimer's disease (AD), but its neurobiological underpinnings remain unclear. We investigated whether locus coeruleus (LC) integrity relates to SWS across the AD continuum and whether sex and perivascular spaces (PVSs) modify these associations.
Neus Falgàs   +20 more
wiley   +1 more source

Cumplimiento del tratamiento odontológico relacionado con enfermedades crónicas en adultos mayores en un centro dental docente peruano

open access: yesMedUNAB
RESUMEN Introducción. La presencia de enfermedades crónicas en adultos mayores puede afectar el cumplimiento del tratamiento odontológico. Por tanto, el objetivo es determinar la asociación entre el cumplimiento del tratamiento odontológico y el número ...
Alfaro-Pacheco, Carlos Eduardo   +2 more
doaj   +1 more source
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