The regeneration process following dLhCG engraftment progressed through four distinct and interconnected stages. dLhCG maintained its regenerative efficacy after 6 months of cosmic exposure, supporting its potential application in space medicine.
Xu Hu +8 more
wiley +1 more source
Defining the impact of Getah virus envelope protein glycosylation site mutations on viral replication, host adaptation, virulence, and immune evasion. [PDF]
Ren T +11 more
europepmc +1 more source
Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim +9 more
wiley +1 more source
ZDHHC11-mediated palmitoylation of viral envelope protein restricts dengue virus replication: implication for the development of universal anti-flavivirus therapeutic strategies. [PDF]
Lai M +8 more
europepmc +1 more source
Environmental nucleic acids (eNA) observations integrate temporal and ecological information across multiple dimensions of an ecological state. Repeated and complementary observations extend biomonitoring from state assessment toward reconstruction of ecological trajectories, including their direction, rate, pathways, progression, recovery, and ...
Wei Xiong, Aibin Zhan
wiley +1 more source
Discovery of a novel envelope protein derived from simian retrovirus 2 for pseudotyping retroviral vectors used for production of CAR immune cells. [PDF]
Jeun M +5 more
europepmc +1 more source
RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad +5 more
wiley +1 more source
A hepcidin homolog from <i>Lateolabrax japonicus</i> inhibits the infection of Anguillid herpesvirus 1 by interacting with the viral envelope protein ORF51. [PDF]
Duan Y, Ge JQ, Meng XZ, Chen F, Wang KJ.
europepmc +1 more source
DNA concentration in harvest affects retrovirus clearance capabilities of protein A chromatography
Abstract Protein A chromatography is a key unit operation in biopharmaceutical purification, widely used to capture monoclonal antibodies (mAbs) from harvest cell culture fluid (HCCF). In addition to its primary function, protein A chromatography is also frequently tested for its ability to remove viruses. Although protein A specifically binds mAbs and
Lukas Döring +7 more
wiley +1 more source
Rapid virus-free production of recombinant yellow fever virus envelope protein and its in-depth biophysical analysis. [PDF]
Schelle L +9 more
europepmc +1 more source

