Results 71 to 80 of about 10,170,179 (340)

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

History of the Reception of Montessori Education in Japan

Espacio, Tiempo y Educación, 2018
This paper focuses on the history of the reception of Montessori Education, and sheds light on the development of childhood education in Japan. From its first adoption in the 1910s until today, the Montessori style of Education has been both praised and ...
Mika Yonezu
doaj   +1 more source

The discourse of climate migration: Unravelling the politics of ASEAN’s environmental policies

Pacific Journalism Review, 2020
Climate change has inevitably created impacts globally ranging from regulatory changes to affecting social communities. Among these impacts, climate migration becomes the unprecedented and significant one.
Anggita Marthin, Louis Budiman
doaj   +1 more source

The atomic simulation environment-a Python library for working with atoms.

Journal of Physics: Condensed Matter, 2017
The atomic simulation environment (ASE) is a software package written in the Python programming language with the aim of setting up, steering, and analyzing atomistic simulations. In ASE, tasks are fully scripted in Python.
Ask Hjorth Larsen, Jens Jørgen Mortensen, J. Blomqvist, I. Castelli, R. Christensen, M. Dulak, J. Friis, M. Groves, B. Hammer, Cory Hargus, E. Hermes, P. C. Jennings, Peter Bjerre Jensen, J. Kermode, J. Kitchin, Esben Leonhard Kolsbjerg, J. Kubal, K. Kaasbjerg, S. Lysgaard, Jón Bergmann Maronsson, Tristan Maxson, T. Olsen, L. Pastewka, Andrew A. Peterson, C. Rostgaard, J. Schiøtz, O. Schütt, M. Strange, K. Thygesen, T. Vegge, L. Vilhelmsen, M. Walter, Z. Zeng, K. Jacobsen   +33 more
semanticscholar   +1 more source

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Initiatives of Ecological Responsibility

Vestnik Volgogradskogo Gosudarstvennogo Universiteta. Seriâ 3, Èkonomika,Èkologiâ, 2015
Preservation of environment is one of the global problems for the mankind. The concept of sustainable development presented at the governmental level in 1987 urged to fix at the interstate level the basic principles of development of humanity in harmony ...
Roman Sergeevich Volodin, Igor Valeryevich Moshkin, Veronika Vasilyevna Khubulova   +2 more
doaj   +1 more source

Learning of Environment(s) and Environment(s) of Learning

Southern African Journal of Environmental Education, 2007
No ...
Chris Reddy, Lesley Le Grange
openaire   +4 more sources

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

FEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source

A stepwise emergence of evolution in the RNA world

FEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Modelo de desenvolvimento, agrotóxicos e saúde: um panorama da realidade agrícola brasileira e propostas para uma agenda de pesquisa inovadora

Revista Brasileira de Saúde Ocupacional
O modelo agrário hegemônico no Brasil está baseado em monocultivos para exportação que são intensivos em tecnologias mecanizadas e no uso de agrotóxicos.
Marcelo Firpo Porto, Wagner Lopes Soares
doaj   +1 more source