Results 91 to 100 of about 25,414,586 (332)
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Numerical Analysis and Geometry Optimisation of Vertical Vane of Room Air-conditioner
MATEC Web of Conferences, 2018 Vertical vanes of room air-conditioners are used to control and direct cold air. This paper aims to study vertical vane as one of the parameters that affect the efficiency of dissipating cold air to a given space.
Al-Obaidi Abdulkareem Sh. Mahdi +3 more
doaj +1 more source
Design response to rising sea levels in the Maldives: A study into aquatic architecture
Frontiers of Architectural Research, 2020 Climate change and rising sea levels present immediate threats to humanity. However, the global catastrophe fails to generate sufficient action. Subject to total submergence within 80 years, this study undertakes an iterative design process seeking ...
Ahdha Moosa, Khoa Do, Emil Jonescu
doaj +1 more source
Influential design factors on occupant satisfaction with indoor environment in workplaces
Building and Environment, 2019 Occupant satisfaction with IEQ (indoor environmental quality) is influenced by many physical and psychological factors. This paper reports the results of a study that investigate influential office design factors on occupant satisfaction relating ...
M. Kwon, H. Remøy, M. van den Bogaard
semanticscholar +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Textiles, environment, design (TED): making theory into textiles through sustainable design strategies, pedagogy and collaboration [PDF]
, 2010 The TED research cluster at Chelsea College of Art and Design, University of the Arts London, is a collective of practice-based design researchers whose main concerns are the consideration of the role that the designer can play in creating textiles that ...
Earley, Rebecca +2 more
core
Adaptive development and maintenance of user-centric software systems [PDF]
, 2004 A software system cannot be developed without considering the various facets of its environment. Stakeholders – including the users that play a central role – have their needs, expectations, and perceptions of a system.
Alspaugh +24 more
core +1 more source
Cultural Memories for Better Place Experience: The Case of Orabi Square in Alexandria, Egypt
Urban Science, 2020 Globalization is associated with significant transformations in city forms and cultural and social performances. Governments and cultural heritage organisations increasingly appreciate the importance of preserving diverse physical cultural heritage ...
Fatmaelzahraa Hussein +2 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source