Results 81 to 90 of about 354,863 (304)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

The Benefits of Improved Environmental Accounting: An Economic Framework to Identify Priorities [PDF]

open access: yes
Improved environmental accounting is increasingly seen by corporate managers and environmental advocates alike as a necessary complement to improved environmental decision-making within the private sector.
Boyd, James
core  

Carbon Accounting for Sustainability and Environmental Management

open access: yes
In the evolving landscape of environmental management and sustainability, the role and impact of carbon accounting is critical. This research monograph entitled Carbon Accounting for Sustainability and Environmental Management provides a comprehensive ...
Rahman, Md Jahidur   +2 more
core   +1 more source

AN EMPIRICAL STUDY OF ENVIRONMENTAL COST DRIVERS [PDF]

open access: yes
This paper draws on Environmental Management Accounting (EMA) literature and cost driver theory to study the nature and role of environmental cost drivers.
Nicolas Berland   +3 more
core   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

CHALLENGES OF ENVIRONMENTAL ACCOUNTING AND TAXATION IN ROMANIA [PDF]

open access: yes
Environmental problems that have arisen all over the world are concerning many controversial aspects that were created due to the advance of industrialization in tandem with scientific and technological development.
Farcane Nicoleta   +2 more
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Atık Yönetimi ve Muhasebesi: Sakarya’daki İşletmeler Üzerinde Bir Araştırma

open access: yesAkademik İncelemeler Dergisi, 2014
İşletmeler katma değer yaratırken faaliyetleri gereği çevresel kaynakları kullanmak durumundadırlar. İşletmelerin üretimleri sırasında mal ve hizmet çıktıları ile birlikte, katı, sıvı, gaz atıkları ve tehlikeli atıklar ortaya çıkmaktadır. Ortaya çıkan bu
Hilmi Kırlıoğlu, Meral Erol Fidan
doaj  

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