Results 81 to 90 of about 1,526,678 (287)
Preserving or escaping? On the welfare effects of environmental self-protective choices [PDF]
In modern societies individuals often try to alleviate their personal damages from environmental degradation by increasing their consumption of private goods. Although this “self-protective” behavior is very frequent in industrial economies, insufficient
Antoci, Angelo, Borghesi, Simone
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
A Framework for analyzing socioeconomic, health and environmental impacts of wastewater use in agriculture in developing countries [PDF]
Waste water management / Environmental degradation / Waterborne diseases / Water quality / Irrigation practices / Aquaculture / Economic analysis / Social aspects / Health / Environmental aspects / Agriculture / Developing countries ...
Hanjra, M. A. +4 more
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Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Values of Ecosystem Services Associated with Intense Dairy Farming in New Zealand [PDF]
The increase in greenhouse gas emissions and degradation of water quality and quantity in waterways due to dairy farming in New Zealand have become of growing concern.
Cullen, Ross +3 more
core +1 more source
Testing the orthodoxies of land degradation policy in Swaziland [PDF]
, 2009 This paper explores Swaziland's National Action Programme (NAP) to combat desertification; the country's main strategy for implementing the United Nations Convention to Combat Desertification (UNCCD).
Stringer, L.C.
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Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Cogent Economics & Finance, 2017 Significant number of crude oil pipeline vandalism in the Niger delta region of Nigeria were carried out by the militant groups on the pretext for a better environmental management and development of the region.
Ahmed Tukur Umar +1 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Ecotourism and environmental conservation in small islands in the east coast of peninsular Malaysia [PDF]
, 2009 Many small islands off the east coast of Peninsular Malaysia have become wellknown destinations both to foreign as well as local tourists. However, as tourism authorities, hotels and tour operators increasingly focus on mass tourism and economics ...
Chan, Ngai Weng
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