An integrative assessment to determine the genotoxic hazard of estuarine sediments: combining cell and whole-organism responses [PDF]
, 2014 The application of the Comet assay in environmental monitoring remains challenging in face of the complexity of environmental stressors, e.g., when dealing with estuarine sediments, that hampers the drawing of cause-effect relationships.
Caeiro, Sandra +8 more
core +1 more source
Mechanism of DNA Recognition at a Viral Replication Origin [PDF]
, 2006 Recognition of the DNA origin by the Epstein-Barr nuclear antigen 1 (EBNA1) protein is the primary event in latentphase genome replication of the Epstein-Barr virus, a model for replication initiation in eukaryotes.
de Prat Gay, Gonzalo +3 more
core +1 more source
Environmental DNA for improved detection and environmental surveillance of schistosomiasis [PDF]
Proceedings of the National Academy of Sciences, 2019 Significance Accurate detection and delineation of schistosomiasis transmission sites will be vital in ongoing efforts to control and ultimately eliminate one of the most neglected tropical parasitic diseases affecting >250 million people worldwide. Conventional methods to detect parasites in the environment are cumbersome and have
Mita E. Sengupta +11 more
openaire +5 more sources
Interplay of space radiation and microgravity in DNA damage and DNA damage response [PDF]
, 2017 In space, multiple unique environmental factors, particularly microgravity and space radiation, pose constant threat to the DNA integrity of living organisms.
Lu, Tao +4 more
core +2 more sources
An MLSA-based online scheme for the rapid identification of Stenotrophomonas isolates [PDF]
, 2011 An online scheme to assign Stenotrophomonas isolates to genomic groups was developed using the multilocus sequence analysis (MLSA), which is based on the DNA sequencing of selected fragments of the housekeeping genes ATP synthase alpha subunit (atpA ...
Barbosa, Heloiza Ramos +8 more
core +3 more sources
Environmental DNA test validation guidelines.
, 2022 These Environmental DNA test validation guidelines provide harmonised quality control and minimum standard considerations for developing or validating eDNA/eRNA assays for the purpose of single-species or multi-species detection. This document is a comprehensive guide for the development and use of eDNA/eRNA tests, recommended and curated by eDNA ...
De Brauwer, M. +23 more
openaire +4 more sources
The Emerging Role of Ten-Eleven Translocation 1 in Epigenetic Responses to Environmental Exposures. [PDF]
, 2020 Mounting evidence from epidemiological studies and animal models has linked exposures to environmental factors to changes in epigenetic markers, especially in DNA methylation.
Brown, Anthony P, Ji, Hong, Zhu, Tao
core
Mutations in pathways depending on BRCA1 and BRCA2 may increase cancer risks from an environmental carcinogen [PDF]
, 2011 Recently, the President’s Cancer Panel [2008-2009] protested that preventive action is not taken when uncertainty exists about potential harm from a chemical, because the US regulatory approach demands that a hazard be incontrovertibly ...
Bernard Friedenson
core +2 more sources
Knowledge and Management of Aquatic Ecosystems, 2022 White-clawed crayfish (Austropotamobius pallipes) is a keystone species found in western European freshwater bodies, where it has suffered drastic declines due to pathogens, competition with non-indigenous crayfish species (NICS) and habitat ...
Mirimin Luca +11 more
doaj +1 more source
Blinking statistics of a molecular beacon triggered by end-denaturation of DNA
, 2005 We use a master equation approach based on the Poland-Scheraga free energy for DNA denaturation to investigate the (un)zipping dynamics of a denaturation wedge in a stretch of DNA, that is clamped at one end.
Ambjörnsson T +13 more
core +1 more source