Results 51 to 60 of about 1,312,280 (331)

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Interdisciplinary Foundations for Environmental and Sustainability Ethics: An Introduction

open access: yesEthics in Progress, 2014
This article introduces the special issue for Ethics in Progress entitled Environment, ethics, and sustainability: Crossroads of our future. Despite four decades of intense development in the field of academic and professional environmental ethics ...
Małgorzata Dereniowska, Jason Matzke
doaj   +3 more sources

The Ethics of Survival: Responsibility and Sacrifice in Environmental Ethics

open access: yesPhenomenology & Practice, 2013
The primary concern of environmental ethics pushed to the limit is the question of survival. An ethic of survival would concern the possibility of morality in an environmental crisis that promises humanity immeasurable damage, suffering, and even the ...
Ilan Safit
doaj   +1 more source

An Investigation of Obligatory Anthropoholism as Plausible African Environmental Ethics [PDF]

open access: yes, 2019
African ontological discourse revolves around a few principles, the interrelatedness of being, what is variously interpreted as communalism, ubuntu, Holism, communitarianism etc.
Ifeakor, Chinedu S.
core  

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

open access: yesFEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker   +8 more
wiley   +1 more source

A Brief History of Enviroethics and Its Challenges [PDF]

open access: yesJournal of Medical Ethics and History of Medicine, 2009
Environmental ethics has emerged during the early 1970s, when environmentalists started urging philosophers to consider the philosophical aspects of environmental problems. Environmental ethics considers the ethical relationships between humanity and non-
Marjan Laal
doaj   +2 more sources

A Post-environmental Ethics?

open access: yesEthics, Place & Environment, 2003
This essay offers a critique of environmental ethics and argues that a post-environmental ethics may be unavoidable. It does so by exposing and questioning the ontological assumptions common to otherwise different modalities of environmental ethics. These modalities, it is argued, rest upon an implicit or explicit 'material essentialism'.
openaire   +6 more sources

Book review essay: Perspectives on environmental ethics [PDF]

open access: yes, 2009
Most introductory texts in environmental ethics (and philosophy in general) are anthologies, and there are advantages to this approach. No philosopher is an expert on all aspects of the field, especially if practical concerns such as climate change ...
Gunn, Alastair S.
core   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Development Ethics [PDF]

open access: yes, 2016
A 4,000 word overview of the field of development ethics, with special reference to the interface with environmental ethics. The essay outlines characteristic concerns of development ethics, with special attention to issues around the recognition of ...
Gasper, D.R. (Des)
core   +2 more sources

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