Results 61 to 70 of about 1,384,930 (310)

Environmental vices as ethical and anthropological roots of the environmental crisis

open access: yesStudia Ecologiae et Bioethicae, 2020
The root of environmental crisis is not only the failure to recognize the intrinsic value of the non-human world, but it can also be perceived as a failure in moral excellence and in the cultivation of virtue.
Dominika Dzwonkowska
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Epilogue [PDF]

open access: yes, 2009
The Environmental Responsibility Reader is a definitive collection of classic and contemporary environmental works that offers a comprehensive overview of the issues involved in environmental responsibility, steering the reader through each development ...
Blackmore, Chris   +2 more
core  

A new dawn? The Roman Catholic Church and environmental issues [PDF]

open access: yes, 1997
This is a PDF version of an article published in New Blackfriars© 1997. The definitive version is available at www.blackwell-synergy.com.This article discusses the stance of the Roman Catholic Church on environmental issues and argues that the Church ...
ACORA   +15 more
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Logical and Theoretical Foundations of African Environmental Ethics [PDF]

open access: yes, 2016
[English] The paper observed that the various ethics that constitute the system of African environmental ethics are not based on or linked to any known African ontology and formal logic.
Ibanga, Diana-Abasi
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Ethics of Social Consequences and Evolutionary Ontology in Contemporary Environmental Ethics

open access: yesProfil, 2019
The article deals with an analysis, comparison and evaluation of Evolutionary Ontology by Josef Šmajs and Ethics of Social Consequences by Vasil Gluchman.
Martin Pazdera
doaj   +1 more source

Paul Taylors Biocentric Ethics: A Survey of Contemporary Environmental Conflicts [PDF]

open access: yes, 2019
This work is on Paul Taylors Biocentric Ethics: A Survey of Contemporary Environmental Conflicts. When we accept the concept of biocentrism there is bound to exist conflicts between interests and cultural values of humans and the well-being of nonhuman ...
Big-Alabo, Sotonye
core  

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