Results 1 to 10 of about 819,944 (125)

Description and evaluation of the Community Multiscale Air Quality (CMAQ) modeling system version 5.1 [PDF]

open access: yesGeoscientific Model Development, 2017
The Community Multiscale Air Quality (CMAQ) model is a comprehensive multipollutant air quality modeling system developed and maintained by the US Environmental Protection Agency's (EPA) Office of Research and Development (ORD).
K. W. Appel   +22 more
doaj   +1 more source

A transgenic mice model of retinopathy of cblG-type inherited disorder of one-carbon metabolism highlights epigenome-wide alterations related to cone photoreceptor cells development and retinal metabolism

open access: yesClinical Epigenetics, 2023
Background MTR gene encodes the cytoplasmic enzyme methionine synthase, which plays a pivotal role in the methionine cycle of one-carbon metabolism.
Karim Matmat   +14 more
doaj   +1 more source

A harmonized chemical monitoring database for support of exposure assessments

open access: yesScientific Data, 2022
Measurement(s) occurrence of chemicals in environmental and biological media Technology Type(s) mass spectrometry (curation of public data) Sample Characteristic - Organism Homo sapiens • aquatic invertebrates • aquatic vertebrates/mammals • birds • fish
Kristin K. Isaacs   +12 more
doaj   +1 more source

Birch allergen challenges in allergic conjunctivitis using standard conjunctival allergen challenge and environmental exposure chamber

open access: yesClinical and Translational Allergy, 2021
Background Environmental exposure chambers (EECs) have been used extensively to study allergic rhinoconjunctivitis. Few studies have been published using EECs in conjunctivitis only, and none have used conjunctival allergen challenge as a selection ...
Alina Gherasim   +4 more
doaj   +1 more source

Cognitive Impairment Is Associated with AMPAR Glutamatergic Dysfunction in a Mouse Model of Neuronal Methionine Synthase Deficiency

open access: yesCells, 2023
Impairment of one-carbon metabolism during pregnancy, either due to nutritional deficiencies in B9 or B12 vitamins or caused by specific genetic defects, is often associated with neurological defects, including cognitive dysfunction that persists even ...
Ziad Hassan   +9 more
doaj   +1 more source

Nontarget mass spectrometry and in silico molecular characterization of air pollution from the Indian subcontinent

open access: yesCommunications Earth & Environment, 2022
A combination of high-resolution mass spectrometry and computational molecular characterization techniques can structurally annotate up to 17% of organic compounds in fine particulate matter in highly polluted air sampled in the Maldives.
Stefano Papazian   +12 more
doaj   +1 more source

The separation of arsenic metabolites in urine by high performance liquid chromatographyinductively coupled plasma-mass spectrometry [PDF]

open access: yesEnvironmental Health and Toxicology, 2014
Objectives The purpose of this study was to determine a separation method for each arsenic metabolite in urine by using a high performance liquid chromatography (HPLC)- inductively coupled plasma-mass spectrometer (ICP-MS).
Jin-Yong Chung   +5 more
doaj   +1 more source

Impacts of different characterizations of large-scale background on simulated regional-scale ozone over the continental United States [PDF]

open access: yesAtmospheric Chemistry and Physics, 2018
This study analyzes simulated regional-scale ozone burdens both near the surface and aloft, estimates process contributions to these burdens, and calculates the sensitivity of the simulated regional-scale ozone burden to several key model inputs with ...
C. Hogrefe   +8 more
doaj   +1 more source

Adding four-dimensional data assimilation by analysis nudging to the Model for Prediction Across Scales – Atmosphere (version 4.0) [PDF]

open access: yesGeoscientific Model Development, 2018
The Model for Prediction Across Scales – Atmosphere (MPAS-A) has been modified to allow four-dimensional data assimilation (FDDA) by the nudging of temperature, humidity, and wind toward target values predefined on the MPAS-A computational mesh.
O. R. Bullock Jr.   +3 more
doaj   +1 more source

Stemness of Normal and Cancer Cells: The Influence of Methionine Needs and SIRT1/PGC-1α/PPAR-α Players

open access: yesCells, 2022
Stem cells are a population of undifferentiated cells with self-renewal and differentiation capacities. Normal and cancer stem cells share similar characteristics in relation to their stemness properties.
Youssef Siblini   +4 more
doaj   +1 more source

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