Results 81 to 90 of about 2,506,056 (353)

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Retrospective Surveillance of Wastewater To Examine Seasonal Dynamics of Enterovirus Infections

open access: yesmSphere, 2017
Enteroviruses are RNA viruses that are responsible for both mild gastroenteritis and mild respiratory illnesses as well as debilitating diseases such as meningitis and myocarditis.
Nichole E. Brinkman   +2 more
doaj   +1 more source

Fish Advisories: Useful Or Difficult to Interpret? [PDF]

open access: yes, 1996
The authors note that fish and shellfish offer significant exposure to environmental toxins but find that consumer knowledge and other factors may limit efforts to control risk in urban ...
Burger, Joanna, Gochfeld, Michael
core   +1 more source

Mapping environmental injustices: pitfalls and potential of geographic information systems in assessing environmental health and equity. [PDF]

open access: yes, 2002
Geographic Information Systems (GIS) have been used increasingly to map instances of environmental injustice, the disproportionate exposure of certain populations to environmental hazards.
Austin R   +16 more
core   +3 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Multiple pathways of human exposure to poly- and perfluoroalkyl substances (PFASs): From external exposure to human blood

open access: yesEnvironment International, 2020
Exposure to PFASs may result in adverse health effects. This study aimed to characterise the exposure to PFASs from diet, house dust, indoor air, and dermal contact and the relative contribution from different external exposure pathways to human serum ...
Somrutai Poothong   +4 more
doaj   +1 more source

The Emerging Role of Ten-Eleven Translocation 1 in Epigenetic Responses to Environmental Exposures. [PDF]

open access: yes, 2020
Mounting evidence from epidemiological studies and animal models has linked exposures to environmental factors to changes in epigenetic markers, especially in DNA methylation.
Brown, Anthony P, Ji, Hong, Zhu, Tao
core  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Still Toxic After All These Years: Air Quality and Environmental Justice in the San Francisco Bay Area [PDF]

open access: yes, 2007
From West Oakland's diesel-choked neighborhoods to San Francisco's traffic-snarled Mission District to the fenceline communitis abutting Richmond's refineries, poor and minority residents of the San Francisco Bay Area get more than their share of ...
James Sadd   +2 more
core  

Metabolic profiling detects early effects of environmental and lifestyle exposure to cadmium in a human population [PDF]

open access: yes, 2012
Background: The ‘exposome’ represents the accumulation of all environmental exposures across a lifetime. Topdown strategies are required to assess something this comprehensive, and could transform our understanding of how environmental factors affect ...
Athersuch, Toby J.   +10 more
core   +4 more sources

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