The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Retrospective Surveillance of Wastewater To Examine Seasonal Dynamics of Enterovirus Infections
Enteroviruses are RNA viruses that are responsible for both mild gastroenteritis and mild respiratory illnesses as well as debilitating diseases such as meningitis and myocarditis.
Nichole E. Brinkman +2 more
doaj +1 more source
Fish Advisories: Useful Or Difficult to Interpret? [PDF]
The authors note that fish and shellfish offer significant exposure to environmental toxins but find that consumer knowledge and other factors may limit efforts to control risk in urban ...
Burger, Joanna, Gochfeld, Michael
core +1 more source
Mapping environmental injustices: pitfalls and potential of geographic information systems in assessing environmental health and equity. [PDF]
Geographic Information Systems (GIS) have been used increasingly to map instances of environmental injustice, the disproportionate exposure of certain populations to environmental hazards.
Austin R +16 more
core +3 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Exposure to PFASs may result in adverse health effects. This study aimed to characterise the exposure to PFASs from diet, house dust, indoor air, and dermal contact and the relative contribution from different external exposure pathways to human serum ...
Somrutai Poothong +4 more
doaj +1 more source
The Emerging Role of Ten-Eleven Translocation 1 in Epigenetic Responses to Environmental Exposures. [PDF]
Mounting evidence from epidemiological studies and animal models has linked exposures to environmental factors to changes in epigenetic markers, especially in DNA methylation.
Brown, Anthony P, Ji, Hong, Zhu, Tao
core
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Still Toxic After All These Years: Air Quality and Environmental Justice in the San Francisco Bay Area [PDF]
From West Oakland's diesel-choked neighborhoods to San Francisco's traffic-snarled Mission District to the fenceline communitis abutting Richmond's refineries, poor and minority residents of the San Francisco Bay Area get more than their share of ...
James Sadd +2 more
core
Metabolic profiling detects early effects of environmental and lifestyle exposure to cadmium in a human population [PDF]
Background: The ‘exposome’ represents the accumulation of all environmental exposures across a lifetime. Topdown strategies are required to assess something this comprehensive, and could transform our understanding of how environmental factors affect ...
Athersuch, Toby J. +10 more
core +4 more sources

