Results 81 to 90 of about 7,641,268 (406)

Emergence of Urban Heat Traps from the Intersection of Human Mobility and Heat Hazard Exposure in Cities [PDF]

arXiv, 2023
Understanding the relationship between spatial structures of cities and environmental hazard exposures (such as urban heat) is essential for urban health and sustainability planning. However, a critical knowledge gap exists in terms of the extent to which socio-spatial networks shaped by human mobility exacerbate or alleviate urban heat exposures of ...
arxiv  

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Atmospheric oxidation of isoprene and 1,3-butadiene: influence of aerosol acidity and relative humidity on secondary organic aerosol [PDF]

Atmospheric Chemistry and Physics, 2015
The effects of acidic seed aerosols on the formation of secondary organic aerosol (SOA) have been examined in a number of previous studies, several of which have observed strong linear correlations between the aerosol acidity (measured as nmol H+ m−3 air
M. Lewandowski, M. Jaoui, J. H. Offenberg, J. D. Krug, T. E. Kleindienst   +4 more
doaj   +1 more source

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

FEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga, Kazuki Harada, Takuya Yamauchi, Tetsuya Kitaguchi, Masami Yokota Hirai, Mitsuharu Matsumoto, Takashi Tsuboi   +6 more
wiley   +1 more source

Environmental Exposures and ADHD

Environmental Health Perspectives, 2007
In their article, “Exposures to Environmental Toxicants and Attention Deficit Hyperactivity Disorder [ADHD] in U.S. Children,” Braun et al. (2006) advanced our knowledge of the effects of environmental tobacco smoke (ETS) and lead on the central nervous system of children.
openaire   +2 more sources

The formation of secondary organic aerosol from the isoprene + OH reaction in the absence of NO_x [PDF]

Atmospheric Chemistry and Physics, 2009
The reaction of isoprene (C5H8) with hydroxyl radicals has been studied in the absence of nitrogen oxides (NOx) to determine physical and chemical characteristics of the secondary organic aerosol formed.
T. E. Kleindienst, M. Lewandowski, J. H. Offenberg, M. Jaoui, E. O. Edney   +4 more
doaj   +1 more source

Estimation of environmental exposure: interpolation, kernel density estimation or snapshotting

Ann. GIS, 2018
In environmental health researches and practices, spatial analysis became an important approach to estimation of environmental exposure of human subjects under concern.
Xun Shi, Meifang Li, Olivia Hunter, Bart Guetti, A. Andrew, E. Stommel, W. Bradley, M. Karagas   +7 more
semanticscholar   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Redefining environmental exposure for disease etiology

npj Systems Biology and Applications, 2018
Etiological studies of human exposures to environmental factors typically rely on low-throughput methods that target only a few hundred chemicals or mixtures.
S. Rappaport
semanticscholar   +1 more source

Quantifying uncertainty in health impact assessment: a case-study example on indoor housing ventilation. [PDF]

, 2013
Quantitative health impact assessment (HIA) is increasingly being used to assess the health impacts attributable to an environmental policy or intervention.
Bhatia, Briggs, Craig, DCLG, DCLG, de Nazelle, Dimitroulopoulou, Dubois, Emenius, Engvall, Engvall, Fehr, Fisk, Fuentes, Greenland, Hagerhed-Engman, Hänninen, Jaakkola, Jaakkola, Lhachimi, Lhachimi, Li, Liu, Manuel, Maravas, Mesa-Frias, Mesa-Frias, Milton, Norbäck, Nordstrom, Oie, ONS, Rockhill, Rothman, Schram-Bijkerk, Scovronick, Seppanen, Skov, Smithson, Stenberg, Stephens, Sterling, Stymne, Sun, Sundell, Taylor, Trust, Tsai, Veerman, Walinder, Walker, Wargocki, Wright, Zimmermann, Zuraimi   +54 more
core   +1 more source