Results 91 to 100 of about 16,763,260 (343)

Environmental Factors Associated With Type 1 Diabetes

Frontiers in Endocrinology, 2019
Type 1 diabetes (T1D) is a chronic autoimmune disorder that leads to progressive pancreatic ß-cell destruction and culminates in absolute insulin deficiency and stable hyperglycaemia. It is very likely that environmental factors play a role in triggering
S. Esposito, G. Toni, Giorgia Tascini, Elisa Santi, M. G. Berioli, N. Principi   +5 more
semanticscholar   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

FEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito, Yujin Lee, Motoharu Ueno, Naotaka Sekiyama, Masatomo So, Ayako Furukawa, Kenji Sugase   +6 more
wiley   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Temporal-spatial distribution characteristics and associated socioeconomic factors of visiting frequency for rural patients with hypertension in Fujian Province, Southeast China

BMC Public Health
Background Regular follow-up and medication can effectively reduce the risk of adverse outcomes for patients with hypertension. This study aimed to explore the temporal-spatial distribution characteristics and associated socioeconomic factors of visiting
Rong Fu, Zhi Huang, Yulan Lin, Xuwei Tang, Zhenquan Zheng, Zhijian Hu   +5 more
doaj   +1 more source

Epidemiologic evaluation of Nhanes for environmental Factors and periodontal disease

Scientific Reports, 2019
Periodontitis is a chronic inflammation that destroys periodontal tissues caused by the accumulation of bacterial biofilms that can be affected by environmental factors.
P. Emecen-Huja, Hsin-Fang Li, J. Ebersole, J. Lambert, H. Bush   +4 more
semanticscholar   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Environmental factors and multiple sclerosis [PDF]

The Lancet Neurology, 2008
Studies in Canada have provided strong evidence that environmental factors act at a population level to influence the unusual geographical distribution of multiple sclerosis (MS). However, the available data accommodate more than one type of environmental effect.
openaire   +3 more sources

The interaction of occupational stress and job burnout on depressive symptoms in railway workers in Fuzhou city

BMC Public Health
Background To explore the relationship between occupational stress, burnout and depressive symptoms among railroad workers in Fuzhou, and to analyze the interaction of burnout and occupational stress on depressive symptoms.
Shuangjie Yu, Min Zhao, Ye Li, Can Liu, Youjuan Fu, Yu Jiang, Suzhen Guan   +6 more
doaj   +1 more source

Identification of environmental factors that promote intestinal inflammation

Nature, 2022
L. Sanmarco, C. Chao, Yu-Chao Wang, Jessica E. Kenison, Zhaorong Li, Joseph M Rone, C. M. Rejano-Gordillo, C. M. Polonio, Cristina Gutiérrez-Vázquez, Gavin Piester, A. Plasencia, Lu Li, Federico Giovannoni, Hong-Gyun Lee, Camilo Faust Akl, Michael A. Wheeler, I. Mascanfroni, Merja Jaronen, Moneera Alsuwailm, Patrick Hewson, A. Yeste, B. Andersen, D. G. Franks, Chien-Jung Huang, Millicent N Ekwudo, Emily C. Tjon, Veit Rothhammer, M. Takenaka, K. A. de Lima, M. Linnerbauer, Lydia Guo, Ruxandra Covacu, Hugo Queva, Pedro H. Fonseca-Castro, Maha Al Bladi, Laura M. Cox, K. Hodgetts, M. E. Hahn, A. Mildner, J. Korzenik, R. Hauser, S. Snapper, F. Quintana   +42 more
semanticscholar   +1 more source