Results 71 to 80 of about 5,718,297 (303)

MiRNA-34 and stress response [PDF]

open access: yes, 2017
Psychiatric disorders are known to result from a strong interaction between genetic predisposition and environmental factors, mainly exposure to stressful events. Environmental events can modulate genes expression, possibly via epigenetic mechanisms, and
Andolina, Diego   +2 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Analysis of the dynamic correlation between chronic comorbidities and health shocks among middle-aged and older adults people in rural mountainous areas of southern Ningxia—from 14 years of follow-up panel data

open access: yesFrontiers in Public Health
BackgroundWith the acceleration of the aging process, the health shock on the middle-aged and older adults people has become a key issue that urgently needs to be solved.
Juan Yang   +11 more
doaj   +1 more source

The Hippo signaling pathway contributes to the 2,5-Hexadion-induced apoptosis of ovarian granulosa cells

open access: yesJournal of Ovarian Research, 2023
Although n-hexane can induce ovarian damage by inducing ovarian granulosa cell (GC) apoptosis, the mechanism underlying this induction of apoptosis has not been fully elucidated.
Yi Sun   +5 more
doaj   +1 more source

Perceived environmental factors associated with obesity in Libyan men and women [PDF]

open access: yes, 2018
Background: There is a lack of research pertaining to the links between built environment attributes and obesity in adults in the Eastern Mediterranean Region.
Akabayashi   +10 more
core   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Association of prenatal parabens exposure with adverse pregnancy outcomes: the role of prenatal depressive symptoms

open access: yesFrontiers in Public Health
BackgroundParabens (PBs) are common endocrine-disrupting preservatives linked to adverse pregnancy outcomes, while prenatal depressive symptoms are also prevalent and harmful. Their combined effects remain poorly understood.ObjectiveTo examine individual
Mengjun Chang   +16 more
doaj   +1 more source

The Influence of Environmental Factors to the Abundance of Scales (Hemiptera: Diaspididae) Population on Apple Crop [PDF]

open access: yes, 2015
This research aims to assess the environmental factors that affect the abundance of scales populations on the apple crop. The study was conducted in July 2012 to January 2013. The study was conducted at two sites with different altitude.
Abadi, A. L. (Abdul)   +3 more
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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