Results 81 to 90 of about 5,718,297 (303)

The Effects of Environmental Factors on the Dynamic Growth Pattern of Mangrove Avicennia Marina [PDF]

open access: yes, 2012
Avicennia marina is a species of mangrove tree occurs in the intertidal zones of estuarine areas in Asia, including Indonesia. Mangrove within the genus member of Avicennia have long dominated many coastal areas along Semarang and Demak coasts.
Anggoro, S. (Sutrisno)   +2 more
core  

Perceptual impact of environmental factors in sighted and visually impaired individuals [PDF]

open access: yes, 2005
To a visually impaired individual the physical world presents many challenges. For a person with impaired sight, wayfinding through a complex environment is fraught with dangers, both actual and imagined.
Barfield, W.   +6 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Long Non-Coding RNAs and Micro RNAs in Chronic Kidney Disease: Recent Advances and Future Directions—A 5-Year Systematic Review

open access: yesLife
Introduction: Chronic Kidney Disease (CKD) is a leading public health problem worldwide, with limited therapeutic options to halt its progression. Recent evidence implicates non-coding RNAs (ncRNAs), specifically long non-coding RNAs (lncRNAs) and ...
Kanellos Skourtsidis   +6 more
doaj   +1 more source

Analysis of Environmental Factors for Leptospirosis Cases in Tulungagung District [PDF]

open access: yes, 2015
Leptospirosis merupakan penyakit zoonosis. Pada tahun 2012 ditetapkan Kejadian Luar Biasa (KLB) dengan ditemukannya dua kasus leptospirosis di dua kecamatan dengan satu kasus meninggal.
Nugroho, A. (Arief)
core  

Most of the genetic covariation between major depressive and alcohol use disorders is explained by trait measures of negative emotionality and behavioral control [PDF]

open access: yes, 2016
Background Mental health disorders commonly co-occur, even between conceptually distinct syndromes, such as internalizing and externalizing disorders.
Ellingson, J. M   +4 more
core   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Effects of di(2-ethylhexyl) phthalate on glucose homeostasis in rats due to impaired autophagy flux of islet β cells mediated by oxidative stress

open access: yes环境与职业医学
BackgroundDi(2-ethylhexyl) phthalate (DEHP) is the most prevalent environmental endocrine disruptor among phthalate acid esters (PAEs) worldwide. Previous studies have indicated that exposure to DEHP may disrupt glucose metabolism.ObjectiveTo investigate
Hongyang ZHOU   +6 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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