Results 61 to 70 of about 13,240,040 (288)

Analysis of the dynamic correlation between chronic comorbidities and health shocks among middle-aged and older adults people in rural mountainous areas of southern Ningxia—from 14 years of follow-up panel data

Frontiers in Public Health
BackgroundWith the acceleration of the aging process, the health shock on the middle-aged and older adults people has become a key issue that urgently needs to be solved.
Juan Yang, Juan Yang, Shan Liu, Shan Liu, Fei Li, Fei Li, Haodong Meng, Haodong Meng, Hui Qiao, Hui Qiao, Yongxin Xie, Yongxin Xie   +11 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Environmental Sustainability in Practice

, 2017
1. Introduction: What is Environmental Sustainability?2. Sustainability Education3. Environmental Planning and Management4. Sustainable Agriculture5. Geospatial Technologies and Environmental Sustainability6.
Environmental Sustainability Research Centre
core   +1 more source

Association of internet use and health service utilization with self-rated health in middle-aged and older adults: findings from a nationally representative longitudinal survey

Frontiers in Public Health
ObjectiveThis study aims to explore the relationship between internet use and self-rated health among middle-aged and older adults and further investigates the mediating role of health service utilization between internet use and self-rated health ...
Ximin Ma, Ximin Ma, Qi Hu, Qi Hu, Jiahui He, Jiahui He, Wenlong Wang, Wenlong Wang, Kexin Chen, Kexin Chen, Hui Qiao, Hui Qiao   +11 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Environmental and wider economic implications of modifications to environmental tax reform [PDF]

, 2002
The most common definition of Environmental Tax Reform (ETR) is the use of the revenue from environmental taxes to reduce distortionary labour taxes. However, the PETRAS project has shown that there are a number of social and political impediments to ...
Clinch, J. Peter, Dunne, Louise
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Association of prenatal parabens exposure with adverse pregnancy outcomes: the role of prenatal depressive symptoms

Frontiers in Public Health
BackgroundParabens (PBs) are common endocrine-disrupting preservatives linked to adverse pregnancy outcomes, while prenatal depressive symptoms are also prevalent and harmful. Their combined effects remain poorly understood.ObjectiveTo examine individual
Mengjun Chang, Mengjun Chang, Xianjia Li, Xianjia Li, Ye Li, Ye Li, Yueyi Lv, Yueyi Lv, Jin Ji, Jin Ji, Can Liu, Can Liu, Yunyun Du, Yunyun Du, Shuqin Ma, Suzhen Guan, Suzhen Guan   +16 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Childhood leukemia and environmental factors [PDF]

, 2012
One of the Consulted experts: Paula Ambrósio, Lab. de Doenças Hematológicas Malignas, Unidade de Citogenética, Departamento de Genética, Instituto Nacional de Saúde Doutor Ricardo Jorge, Lisboa, Portugal (P.
Health Council of the Netherlands
core