Results 51 to 60 of about 19,657,865 (308)

The Role of Gut Microbiota and Environmental Factors in Type 1 Diabetes Pathogenesis

Frontiers in Endocrinology, 2020
Type 1 Diabetes (T1D) is regarded as an autoimmune disease characterized by insulin deficiency resulting from destruction of pancreatic β-cells. The incidence rates of T1D have increased worldwide.
S. Dedrick, Bharathi Sundaresh, Qian Huang, C. Brady, Tessa P X Yoo, C. Cronin, C. Rudnicki, M. Flood, B. Momeni, J. Ludvigsson, E. Altindis   +10 more
semanticscholar   +1 more source

T2* Magnetic Resonance Imaging Uncovers Hemosiderin Burden in Pediatric Hemophilia: A Call for Sensitive Imaging Biomarkers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hemophilic arthropathy remains the leading morbidity in hemophilia despite modern prophylaxis, and early joint damage may be missed by routine exams. This study explored T2* MRI as a noninvasive biomarker of hemosiderin deposition in pediatric hemophilia.
Jessica Garcia, Tarique Hussain, Jeanne Dillenbeck, Matthew Hammer, Annette von Drygalski, Guy Young, Ayesha Zia   +6 more
wiley   +1 more source

Analysis of health risk factors for older adults living alone in China and establishment and evaluation of a nomogram prediction model

Frontiers in Public Health
ObjectiveTo understand the health status of older adults living alone in China and analyze the influencing factors, so as to provide reference for improving the health status of older adults living alone.MethodsBased on CGSS data from China General ...
Kexin Chen, Kexin Chen, Jiangwei Qiu, Jiangwei Qiu, Wenlong Wang, Wenlong Wang, Qi Hu, Qi Hu, Hui Qiao, Hui Qiao   +9 more
doaj   +1 more source

Environmental Factors and Host Microbiomes Shape Host-Pathogen Dynamics.

Trends in Parasitology, 2020
Microorganisms are increasingly recognized as ecosystem-relevant components because they affect the population dynamics of hosts. Functioning at the interface of the host and pathogen, skin and gut microbiomes are vital components of immunity.
Adriana Bernardo-Cravo, D. Schmeller, A. Chatzinotas, V. Vredenburg, A. Loyau   +4 more
semanticscholar   +1 more source

Bridging the Gap in Neuroblastoma Care: Consensus‐Based Statements With Recommendations for Improved Patient and Caregiver Experiences

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neuroblastoma's complex, heterogeneous biology poses significant diagnostic and therapeutic challenges, often requiring caregivers to absorb complex information and participate in time‐sensitive decisions. However, caregivers often feel unprepared to evaluate options.
Vickie Buenger, Joseph Bauer, Jennifer Diamond, Maggie Fader, Shae Hansen, Jacqueline M. Kraveka, Johanna Schoen, Amber Shearer, Dena Sherwood   +8 more
wiley   +1 more source

Housing conditions, cooking fuels, and health-related quality of life among rural middle-aged and elderly in northwest China: A ten-year balanced panel study

Preventive Medicine Reports
Objective: To investigate the impacts of improving housing conditions and transitioning to clean cooking fuels on health-related quality of life (HRQOL) among middle-aged and elderly populations in rural China.
Kexin Chen, Wenlong Wang, Jiangwei Qiu, Wenqin Guo, Jiancai Du, Baokai Gao, Zhaoyan Hu, Hui Qiao   +7 more
doaj   +1 more source

Some Observations on the Role of Water States for Biological and Therapeutical Effects

Innovative Biosystems and Bioengineering, 2018
The peculiar properties of water are recalled, among them the “memory of water”, underlining the behavior of cell water, whose “ordered” structure is probably due to the endogenous electromagnetic fields generated by organelles inside the cells, such ...
Massimo Scalia, Pasquale Avino, Massimo Sperini, Valentina Viccaro, Albina Pisani, Vincenzo I. Valenzi   +5 more
doaj   +1 more source

Environmental factors influencing the development and spread of antibiotic resistance

FEMS Microbiology Reviews, 2017
Antibiotic resistance and its wider implications present us with a growing healthcare crisis. Recent research points to the environment as an important component for the transmission of resistant bacteria and in the emergence of resistant pathogens ...
J. Bengtsson-Palme, E. Kristiansson, E. Kristiansson, D. Larsson   +3 more
semanticscholar   +1 more source

Genetic and environmental factors in Parkinson’s converge on immune function and inflammation

Movement Disorders, 2020
Idiopathic Parkinson's disease (iPD) is a movement disorder characterized by the degeneration of dopaminergic neurons and aggregation of the protein α‐synuclein.
Elizabeth M. Kline, M. Houser, Mary K. Herrick, P. Seibler, C. Klein, A. West, M. Tansey   +6 more
semanticscholar   +1 more source

Admixture Mapping Reveals Candidate Regions for Methotrexate Neurotoxicity Susceptibility: A Reducing Disparities in Acute Leukemia Consortium Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris, Priya B. Shetty, Olga A. Taylor, Elizabeth G. Atkinson, Melissa A. Richard, M. Monica Gramatges, Mark Zobeck, Sandi Pruitt, Amy Hughes, M. Brooke Bernhardt, Ashley Chavana, Van Huynh, Kathleen Ludwig, Laura Klesse, Kenneth Heym, Timothy Griffin, Rodrigo Erana, Juan Carlos Bernini, Han Chen, Bing Yu, Philip J. Lupo, Karen R. Rabin, Michael E. Scheurer, Austin L. Brown, The REDIAL Consortium   +24 more
wiley   +1 more source