Results 81 to 90 of about 4,643,049 (354)
Checklist for One Health Epidemiological Reporting of Evidence (COHERE). [PDF]
, 2017 One Health is defined as the intersection and integration of knowledge regarding humans, animals, and the environment, yet as the One Health scientific literature expands, there is considerable heterogeneity of approach and quality of reporting in One ...
COHERE Expert Review Group +6 more
core
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Environmental quality conditions in Fairbanks, Alaska, 1972 [PDF]
, 1972 Published by The Institute of Water Resources and The Institute of Social, Economic and Government Research Fairbanks, AlaskaThis study represents a starting point for investigating the nature and interconnectivity of environmental quality problems ...
Pearson, Roger W., Smith, Daniel W.
core
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Revista Brasileira de Epidemiologia, 2011 INTRODUÇÃO: A poluição do ar é um problema importante para o município de São Paulo, cuja maior fonte são os veículos. Cerca de 11 milhões de habitantes estão expostos a essa poluição.
Giovana Iara Ferreira Moser de Toledo +1 more
doaj +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Environmental Health Risk Analysis Exposure to Nitrogen Dioxide (No2) and Sulfur Dioxide (So2) on Street Vendor in Ampera Terminal Palembang 2015 [PDF]
, 2015 Background: Terminal is a location that generates air pollution as a result of transport activity performed. The use of motorized transport will produce a wide range of gases including NO2 and SO2.
Arista, G. (Gita) +2 more
core
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source