Results 81 to 90 of about 12,997,483 (306)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Impact of Green Building Implementation on Health and Well-being of Building Users in Indonesia

open access: yesJurnal Presipitasi
This research conducts a systematic literature review, adopting the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, to examine the impact of green building implementation on health and well-being of users in Indonesia.
Lendra Lendra   +2 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Neurological and mental health in the era of climate change: mechanisms, clinical impacts, and adaptation

open access: yesFrontiers in Public Health
Climate change has become a global health emergency in recent decades, with far-reaching effects on neurological and psychiatric health; however, their relationship remains poorly understood.
Pablo S. Martínez Lozada   +1 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

A case study of long-term disease burden in a rural community near an open burn facility

open access: yesExperimental Biology and Medicine
Open burning and open detonation (OB/OD) of explosive and hazardous wastes creates various toxic waste products, including particulate matter, that is released into the atmosphere and capable of generating significant health impacts upon exposure.
Arundhati Bakshi   +6 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Individual interventions to reduce nighttime light exposure in a representative sample of adults aged 18–64 years in Poland

open access: yesInternational Journal of Occupational Medicine and Environmental Health
Objectives Exposure to nighttime light pollution has a multidimensional environmental impact and is associated with harmful health effects. This study aimed to characterize individual interventions to reduce nighttime light exposure among adults in ...
Radosław Sierpiński   +2 more
doaj   +1 more source

Environmental disease monitoring by regional Environmental Health Centers in Korea: a narrative review [PDF]

open access: yesThe Ewha Medical Journal
This study explores the development, roles, and key initiatives of the Regional Environmental Health Centers in Korea, detailing their evolution through four distinct phases and their impact on environmental health policy and local governance.
Myung-Sook Park   +20 more
doaj   +1 more source

Exposure to environmental chemicals among Korean adults-updates from the second Korean National Environmental Health Survey (2012-2014).

open access: yesInternational Journal of Hygiene and Environmental Health, 2017
National biomonitoring program can offer solid scientific evidence on exposure profiles of environmental chemicals at a national level, and provide a snapshot of changing exposure level over time.
Wookhee Choi   +7 more
semanticscholar   +1 more source

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