Results 131 to 140 of about 5,915,013 (307)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Heterogeneous relations among environmental regulation, technological innovation, and environmental pollution

open access: yesHeliyon
In this study, interprovincial panel data of China from 2011 to 2020 are selected and empirically examined to determine the effects of three types of environmental regulation tools: command-and-control, market-incentive, and public-participation types. Then, hierarchical regression analysis and instrumental variables are used to analyze and verify the ...
Zhilong You, Guisheng Hou, Min Wang
openaire   +3 more sources

Heterogeneity in Costs and Second-Best Policies for Environmental Protection [PDF]

open access: yes
This paper investigates heterogeneity in pollution abatement costs using a computable general equilibrium framework. Previous literature using aggregated data has found that "grandfathered" tradable permits are dominated by other instruments including ...
Cannon, Matthew, Burtraw, Dallas
core  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Environmental instability in heterogeneous domains

open access: yes, 2016
Species interaction models have been widely studied to investigate the phenomena of population fluctuations and extinction. To a great degree, these models have assumed that the environment is spatially homogeneous, although discrete 'patch models' suggested that movement between patches has important global implications.
Maini, P, Benson, D, Sherratt, J
openaire   +1 more source

Heterogeneity and the Voluntary Provision of Public Goods [PDF]

open access: yes
We investigate the effects of heterogeneity, incomplete information and communication on aggregate contributions to a public good using the voluntary contribution mechanism in a nonlinear laboratory environment.
Kenneth S. Chan   +3 more
core  

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Changes in Fish Taxonomic and Phylogenetic Diversity and Their Driving Factors in a Reservoir in the Karst Basin of Southwest China

open access: yesAnimals
Dam construction can significantly alter local habitat characteristics and the distribution patterns of aquatic organisms. However, the variations in the multidimensional diversity of fish assemblages in reservoirs, as well as the relative significance ...
Jialing Qiao   +6 more
doaj   +1 more source

Investigating distance effects on environmental values: a choice modelling approach [PDF]

open access: yes
Analysis of the relationship between distance and willingness to pay (WTP) is important for estimation and transfer of environmental benefits. Several contingent valuation (CV) studies have investigated this topic, but results are mixed.
Concu, Giovanni B.
core  

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

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