Results 151 to 160 of about 971,459 (303)

Determinants of Pollution Abatement and Control Expenditure in Romania: A Multilevel Analysis [PDF]

The transition process in Central and Eastern Europe was associated with growing environmental awareness. This paper analyses the determinants of Pollution Abatement and Control Expenditure (PACE) at plant level in the case of Romania using survey data ...
Anamaria Sova, Christophe Rault, Guglielmo Maria Caporale, Robert Sova   +3 more
core  

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Geographic isolation and environmental heterogeneity contribute to genetic differentiation in Cephalotaxus oliveri. [PDF]

Ecol Evol, 2023
Liu H, Wang Z, Zhang Y, Li M, Wang T, Su Y.   +5 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Random Utility Models of Recreational Fishing: Catching Fish Using a Poisson Process [PDF]

This paper presents a Poisson model of expected angler catch during a sportfishing trip and employs the expected catch in a random utility model of site choice.
Blake-Hedges, Lynne, McConnell, Kenneth E., Strand, Ivar E., Jr.   +2 more
core   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Environmental heterogeneity modulates the effect of plant diversity on the spatial variability of grassland biomass. [PDF]

Nat Commun, 2023
Daleo P, Alberti J, Chaneton EJ, Iribarne O, Tognetti PM, Bakker JD, Borer ET, Bruschetti M, MacDougall AS, Pascual J, Sankaran M, Seabloom EW, Wang S, Bagchi S, Brudvig LA, Catford JA, Dickman CR, Dickson TL, Donohue I, Eisenhauer N, Gruner DS, Haider S, Jentsch A, Knops JMH, Lekberg Y, McCulley RL, Moore JL, Mortensen B, Ohlert T, Pärtel M, Peri PL, Power SA, Risch AC, Rocca C, Smith NG, Stevens C, Tamme R, Veen GFC, Wilfahrt PA, Hautier Y.   +39 more
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Stratified genome-wide association analysis of type 2 diabetes reveals subgroups with genetic and environmental heterogeneity. [PDF]

Hum Mol Genet, 2023
Christiansen CE, Arathimos R, Pain O, Molokhia M, Bell JT, Lewis CM.   +5 more
europepmc   +1 more source