Results 161 to 170 of about 5,915,013 (307)

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

The effect of aggregation on the magnitude of behavioral heterogeneity. [PDF]

Recent literature has shown that the magnitude of behavioral heterogeneity of a population has an impact on the structure of mean demand. This paper investigates the effect of aggregation on the magnitude of behavioral heterogeneity if we aggregate ...
Ralf Wilke
core  

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

On heterogeneity in environmental economic valuation

On heterogeneity in environmental economic valuation
identifier:oai:t2r2.star.titech.ac.jp ...
openaire   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

Geographic isolation and environmental heterogeneity contribute to genetic differentiation in Cephalotaxus oliveri. [PDF]

Ecol Evol, 2023
Liu H, Wang Z, Zhang Y, Li M, Wang T, Su Y.   +5 more
europepmc   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

From environmental heterogeneity to stability: Beta-diversity stabilizes biomass across space. [PDF]

Ecology
Brunner B, Hagan JG, Hassellöv J, Murata JM, Martins LC, de La Patelliere P, Schrofner-Brunner E, Gamfeldt L.   +7 more
europepmc   +1 more source

Environmental heterogeneity modulates the effect of plant diversity on the spatial variability of grassland biomass. [PDF]

Nat Commun, 2023
Daleo P, Alberti J, Chaneton EJ, Iribarne O, Tognetti PM, Bakker JD, Borer ET, Bruschetti M, MacDougall AS, Pascual J, Sankaran M, Seabloom EW, Wang S, Bagchi S, Brudvig LA, Catford JA, Dickman CR, Dickson TL, Donohue I, Eisenhauer N, Gruner DS, Haider S, Jentsch A, Knops JMH, Lekberg Y, McCulley RL, Moore JL, Mortensen B, Ohlert T, Pärtel M, Peri PL, Power SA, Risch AC, Rocca C, Smith NG, Stevens C, Tamme R, Veen GFC, Wilfahrt PA, Hautier Y.   +39 more
europepmc   +1 more source